3篇
您的检索式：作者名="Hanhui Yang"
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| 1 | Genome sequence and evolution of Betula platyphylla显示文摘Betula L.(birch)is a pioneer hardwood tree species with ecological,economic,and evolutionary importance in the Northern Hemisphere.We sequenced the Betula platyphylla genome and assembled the sequences into 14 chromosomes.The Betula genome lacks evidence of recent whole-genome duplication and has the same paleoploidy level as Vitis vinifera and Prunus mume.Phylogenetic analysis of lignin pathway genes coupled with tissue-specific expression patterns provided clues for understanding the formation of higher ratios of syringyl to guaiacyl lignin observed in Betula species.Our transcriptome analysis of leaf tissues under a time-series cold stress experiment revealed the presence of the MEKK1–MKK2–MPK4 cascade and six additional mitogen-activated protein kinases that can be linked to a gene regulatory network involving many transcription factors and cold tolerance genes.Our genomic and transcriptome analyses provide insight into the structures,features,and evolution of the B.platyphylla genome.The chromosome-level genome and gene resources of B.platyphylla obtained in this study will facilitate the identification of important and essential genes governing important traits of trees and genetic improvement of B.platyphylla. | Su Chen Yucheng Wang Lili Yu Tao Zheng Sui Wang Zhen Yue Jing Jiang Sapna Kumari Chunfang Zheng Haibao Tang Jun Li Yuqi Li Jiongjiong Chen Wenbo Zhang Hanhui Kuang Jon SRobertson Patrick XZhao Huiyu Li Shengqiang Shu Yordan SYordanov Haijiao Huang David MGoodstein Ying Gai Qi Qi JiuMeng Min ChunYan Xu SongBo Wang Guan-Zheng Qu Andrew HPaterson David Sankoff Hairong Wei Guifeng Liu Chuanping Yang | 2021 | Horticulture Research2021，8，1： | 1 |
| 2 | Fast MRI Reconstruction via Edge Attention显示文摘Fast and accurate MRI reconstruction is a key concern in modern clinical practice.Recently,numerous Deep-Learning methods have been proposed for MRI reconstruction,however,they usually fail to reconstruct sharp details from the subsampled k-space data.To solve this problem,we propose a lightweight and accurate Edge Attention MRI Reconstruction Network(EAMRI)to reconstruct images with edge guidance.Specifically,we design an efficient Edge Prediction Network to directly predict accurate edges from the blurred image.Meanwhile,we propose a novel Edge Attention Module(EAM)to guide the image reconstruction utilizing the extracted edge priors,as inspired by the popular self-attention mechanism.EAM first projects the input image and edges into Q_(image),K_(edge),and V_(image),respectively.Then EAM pairs the Q_(image)with K_(edge)along the channel dimension,such that 1)it can search globally for the high-frequency image features that are activated by the edge priors;2)the overall computation burdens are largely reduced compared with the traditional spatial-wise attention.With the help of EAM,the predicted edge priors can effectively guide the model to reconstruct high-quality MR images with accurate edges.Extensive experiments show that our proposed EAMRI outperforms other methods with fewer parameters and can recover more accurate edges. | Hanhui Yang Juncheng Li Lok Ming Lui Shihui Ying Jun Shi Tieyong Zeng | 2023 | Communications in Computational Physics2023，33，5： | 0 |
| 3 | The local density of H3K9me3 dictates the stability of HP1α condensates-mediated genomic interactions显示文摘The human genome can be demarcated into domains based on distinct epigenetic states.The trimethylation of histone H3 lysine 9(H3K9me3)is essential for the formation of constitutive heterochromatin nanodomains.However,the extent to which genomic regions require specific densities or degrees of H3K9me3 for stable interactions remains unclear.Here,we utilize CRISPR-based DNA imaging to investigate the role of endogenous or ectopic H3K9me3 in chromatin dynamics and genomic interactions.We select three loci(IDR3,TCF3,and PR1)with distinct levels of H3K9me3 to examine the genomic interactions and association with endogenous Heterochromatin Protein 1(HP1α)condensates.Our results demonstrate a positive correlation between the levels of H3K9me3 at the loci and their association with HP1αcondensates.By dual-color labeling and long-term tracking of IDR3 and PR1 loci,we find a periodical association between the two ranging from one to three hours.Epigenetic perturbation-induced Genome organization(EpiGo)-KRAB introduces∼20 kilobases of H3K9me3 at the TCF3 locus,which is sufficient to establish a stable association between TCF3 and HP1αcondensates.In addition,EpiGo-mediated H3K9me3 also leads to stable genomic interaction between IDR3 and TCF3.Briefly,these data suggest that the density of H3K9me3 could dictate the stability of interactions between genomic loci and HP1αcondensates. | Ying Feng Li Guo Chen Yang Hui Zheng Xiao Xiao Hanhui Ma | 2023 | Journal of Genetics and Genomics2023，50，10： | 0 |
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