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您的检索式：作者名="Hanpei Wang"
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| 1 | Losses of Ecosystem Service Values in the Taihu Lake Basin from 1979 to 2010显示文摘 | Hui ZHANG Qiao WANG Guangyu LI Hanpei ZHANG Jue ZHANG | 2017 | Frontiers of Earth Science2017，11，2： | 7 |
| 2 | Relationship between carotid plaque and serum uric acid in patients with cerebral infarction显示文摘 | Gu Hanpei Chen Xiaodong Wang Guangsheng | 2011 | Chinese Journal of practical neurological diseases2011，24，17： | 1 |
| 3 | Development of a UPLC–MS/MS method for determination of pimavanserin tartrate in rat plasma: Application to a pharmacokinetic study显示文摘A simple, rapid and sensitive method based on an ultra-performance liquid chromatography–tandem mass spectrometry(UPLC–MS/MS) has been developed and validated for the determination of pimavanserin in rat plasma. The analyte was extracted by protein precipitation with methanol and separated on an ACQUITY BEH C_(18) column(100 mm × 2.1 mm, 1.7 μm; Waters, USA), with an isocratic elution of acetonitrile-water containing 10 mM ammonium acetate(70:30, v/v), at a flow rate of 0.2 m L/min for 2.5 min. The analyte and clarithromycin(the internal standard) were detected and quantified in positive ion mode using multiple reaction monitoring transitions at m/z 428.2 → 223.0 for pimavanserin and m/z 748.5 → 589.5 for clarithromycin. Relative coefficient(r) for the calibration curve was more than 0.9980. The intra-day and inter-day precisions(relative standard deviation, RSD%) were less than 13.3% and 10.5%, respectively, and the accuracy(relative error, RE%) was within ± 11.5%. The analytical method was successfully applied to a routine pharmacokinetic study of pimavanserin in rats after oral administration at the dose of 10 mg/kg. | Shixiao Wang Yang Wang Shuang Gao Yuanyuan Zhang Hanpei Wang Longshan Zhao Kaishun Bi Shaojie Wang Xiaohui Chen | 2017 | Journal of Pharmaceutical Analysis2017，7，6： | 0 |
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