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| 1 | Characterization of event-related potentials in obsessive compulsive disorder patients: Comparison with depression and generalized anxiety disorder patients显示文摘BACKGROUND: Study results of event-related potential in obsessive compulsive disorder (OCD) remain controversial, potentially as a result of different instruments utilized and their differing technical characteristics. OBJECTIVE: To investigate the differences in several common event-related potentials, i.e. contingent negative variations, P300, and mismatch negativity (MMN), in OCD patients, depression patients, generalized anxiety disorder (GAD) patients, and healthy controls. DESIGN, TIME AND SETTING: A case-control study was performed in the Department of Electrophysiology, Shanghai Mental Health Center from May 2002 to December 2005. PARTICIPANTS: A total of 38 OCD patients, 20 depression patients, and 18 GAD patients, who were diagnosed according to the criteria of Chinese Classification of Mental Disorders (Version 3), formulated by the Chinese Psychiatry Association, were selected from the Outpatient Department o Shanghai Mental Health Center. Patients with two or more the above diseases were excluded. In addition, 28 healthy people, gender and age matched, were selected as controls. METHODS: Contingent negative variations, P300, and MMN were recorded by a Nicolet Spirit Instrument. All electrodes were attached at Cz according to the International 10-20 system, with the mastoid leads as reference and Fpz as ground. MAIN OUTCOME MEASURES: Amplitude and latency of contingent negative variations, P300, and MMN. RESULTS: The contingent negative variations, P300, and MMN were different (P < 0.01). OCD patients showed an increased M1 amplitude compared with controls, depression, and GAD patients (P < 0.01). Target P300 amplitudes were significantly lower in OCD, depression, and GAD patients compared with controls (P < 0.01). Moreover, N2 latency and latency of MMN were prolonged in OCD and depression groups compared with controls (P < 0.05). CONCLUSION: Event-related potentials were different in depression, GAD, and OCD patients and healthy controls. In particular, OCD patients exhibited unique characteristics. | Yingzhi Lu Wenbin Zong Hanzhen Dong Faxin Wang Jinyu PU Xingshi Chen Yunxiang Tang | 2010 | Neural Regeneration Research2010，5，12： | 5 |
| 2 | Effects of sleep deprivation on polysomnography and executive function in patients with depression显示文摘 | Lu Yingzhi Ren Qingtao Zong Li Wu Yingli Zhang Qinfeng Ma Xiuqing Pu Jinyu Dong Hanzhen Liu Qingqing Tang Yunxiang Song Lisheng Chen Xingshi Pan Xiao Cui Yi | 2014 | Chinese Medical Journal2014，，18： | 2 |
| 3 | Mn,N co-doped Co nanoparticles/porous carbon as air cathode for highly efficient rechargeable Zn-air batteries Hide Author's Information显示文摘Oxygen reduction reaction(ORR)and oxygen evolution reaction(OER)are generally catalyzed by precious metals(Pt)and metal oxides(IrO_(2))which still have many shortages including expensive price,poor selectivity and undesirable stability.In this work,we report a Mn0-doped CoN_(x) on N-doped porous carbon(Mn-CoN_(x)/N-PC)composite from carbonizing metal-organic framework(MOF)derivative as the dual-functional catalyst to boost both the ORR and OER performances.Owing to the strong coordination effect between nitrogen and metal elements,the introduction of N can obviously improve the content of Co-N-C active sites for ORR.Meanwhile,the Mn-doping significantly regulates the electronic structure of the Co element and increases the content of Co^(0) which provide efficient OER active sites.Mn-CoN_(x)/N-PC catalyst delivers super dual-functional activity with a half-wave potential of 0.85 V,better than the 20%Pt/C catalyst(0.82 V).When used in Zn-air batteries for testing,Mn-CoN_(x)/N-PC electrocatalyst shows a high power density(145 mW·cm^(−2))and good cycle performance. | Hanzhen Zheng Fei Ma Hongcen Yang Xiaogang Wu Rui Wang Dali Jia Zhixia Wang Niandi Lu Fen Ran Shanglong Peng | 2022 | Nano Research2022，15，3： | 2 |
| 4 | 显示文摘 | YUAN Hanzhen ZHAO Sui CHENG Gongzhen | 2001 | J Phys Chem:B2001，105，： | 1 |
| 5 | Self-aggregation of surfactants in water solution by NMR显示文摘 | Yuan Hanzhen Du Youru Zhao Sui Yu Jiayong | 1999 | Science in China Series A: Mathematics1999，，3： | 1 |
| 6 | 显示文摘 | YUAN Hanzhen CHENG Gongzhen ZHAO Sui | 2000 | Langmuir2000，16，： | 1 |
| 7 | 显示文摘 | YUAN Hanzhen MIAO Xiajia ZHAO Sui | 2001 | Magn Reson Chem2001，39，： | 1 |
| 8 | 显示文摘 | YUAN Hanzhen LUO Pingya ZHANG L | 2002 | Colloid Polymer Sci2002，280，： | 1 |
| 9 | 显示文摘 | HANZhen YUNCai-xing JIANGXue-zhong(韩震 恽才兴 蒋雪中) | | 水利学报0，，： | 1 |
| 10 | Management of Chinese Foreign Direct Investment:"One Belt, One Road" Across Eurasia to Africa and Europe Amidst Maritime Tensions in the South China Sea Region显示文摘Outward Foreign Direct Investment (OFDI) from the People's Republic of China ("China") has been expandingworldwide, much as Inward Foreign Direct Investment (IFDI) from the world into China has burgeoned, at leastuntil very recently. Global FDI declined worldwide in 2014, with China's IFDI declining less than many placeselsewhere, resulting in China overtaking the United States as the world's most attractive location for FDI for thefirst time since 2003, before India overtook China in 2015 (Iyengar, 2015). In 2014, meanwhile, for the first time,China's OFDI exceeded its IFDI, rendering it a net exporter of FDI, signaling the end of the approach to the end ofChina as a developing nation (Yao & Wang, 2014). What does this mean? More than anything else, one mustconsider two factors in assessing China's 21st century foreign ambitions: Is its One Belt, One Road (OBOR) ageopolitical tetrahedron as some allege, if so, economically or militarily? Is its maritime policy across the WesternPacific Rim of Asia aimed at constructing a fleet of surface cruisers and submarines to wage a guerre de course(war of the chase), much as German vice admiral Wolfgang Wegener urged Imperial Germany to do in world War Ithen Nazi Germany to do in World War II, in an effort to dominate merchant sea routes thereby disrupting supplieswithout recourse to a "balanced fleet" such as Britain possessed in World Wars I and II and the United Statesoperates currently? Both China's "New Silk Road" and the "New Maritime Silk Route" are at the root of ageopolitical tetrahedron. Chinese domination of the South China Sea and to a lesser extent of the East China Searegions signals its potential guerre de course strategy. Is there an antidote to conflict in Asia, if so, what is it? | David A. Jones Hanzhen Liu | 2017 | International Relations and Diplomacy2017，5，8： | 0 |
| 11 | Fixed Bleeding Point by Ligating and Lienectomy Monocarpic Curing Massive Haemorrhage Drastically Leaded by Esophageal Varicose Vein显示文摘 | YU Hanzhen | 2005 | 美国中华健康卫生杂志2005，8，4： | 0 |
| 12 | Molecular and nanostructure designed superhydrophilic material with unprecedented antioil-fouling property for diverse oil/water separation显示文摘The design and development of new advanced superwetting porous membranes with antioil-fouling performance are still rare and highly desirable because of their potential widespread applications.A metallic phosphate nanoflower-covered mesh membrane with superhydrophilic and unprecedented antioil-fouling properties is prepared by an exceptionally simple and effective in-situ solution corrosion method.As demonstrated,the outstanding antioil-fouling property of the resulting mesh membrane is connected with the special phosphate group and the three-dimensional(3 D) nanoflower structure.Owing to the antioil-fouling property,upon to water,the oil-fouled mesh membrane can keep the surface free of various kinds of oils,including viscous crude oil to light n-hexane.Thanks to its unprecedented self-cleaning property,the superhydrophilic mesh membrane can effectively separate different oil/water mixtures without prior wetted by water,exhibiting great potential for practical spilled oil remediation. | WANG ZheCun GUAN Min YANG Xin LI HanZhen WANG LaiGui | 2022 | Science China(Technological Sciences)2022，65，6： | 0 |
| 13 | 亚毒性浓度下顺铂联合SGI-1776体外诱导人卵巢癌细胞凋亡(英文)显示文摘Objective: The aim of the study was to investigate the effect of SGI-1776 combination with DDP in sub-toxic concentration on induction of apoptosis of human ovarian cancer HO-8910 cells in vitro and to unravel the associated mechanisms. Methods: Human ovarian cancer HO-8910 cells were cultured in vitro. The inhibitory effect of SGI-1776 combination with DDP in sub-toxic concentration on induction on viability of human ovarian cancer HO-8910 cells was evaluated by the MTT assay. Cell apoptosis rate was analyzed by flow cytometry. The proteins expression level related to apoptosis were analyzed by Western blot. Results: SGI-1776 combination with DDP in sub-toxic concentration significantly inhibited the proliferation of human ovarian cancer HO-8910 cells, and proliferation inhibition rate was increased drastically compared with normal saline(NS) group or DDP group in sub-toxic concentration or SGI-1776 group in sub-toxic concentration(P﹤0.01). Apoptosis rate markedly increased after the treatment of SGI-1776 combination with DDP in sub-toxic concentration for 48 h. Western blot showed that the expression of bcl-2 protein was down-regulated and protein level of Bax and Cyto-c were depressed by SGI-1776 combination with DDP in sub-toxic concentration. Conclusion: SGI-1776 combination with DDP in sub-toxic concentration could inhibit the cell proliferation and lead to cell apoptosis inhuman ovarian cancer HO-8910 cells, and its mechanism may be related to through mitochondrial apoptotic pathway. | Jun Bai Yingxia Ning Yanfen Chen Hanzhen He Wanyu Xie | 2014 | The Chinese-German Journal of Clinical Oncology2014，13，12： | 0 |
| 14 | 六棱菊总黄酮体外抑制人卵巢癌HO-8910细胞增殖及其机制(英文)显示文摘Objective: The purpose of this study was to investigate the effect of Laggera alata flavonen(LAF) on the inhibiting effect of human ovarian cancer HO-8910 cells proliferation and its possible mechanism in vitro. Methods: Human ovarian cancer HO-8910 cells were cultured in vitro. Inhibitory effect of LAF on the viability of HO-8910 cells was evaluated by the MTT assay. Apoptotic effect of different concentrations of LAF on HO-8910 cells was assessed by AO/EB staining and FCM with propidium iodide(PI) staining. Expression of proteins related to apoptosis was analyzed by Western blot. Results: LAF significantly inhibited the viability of HO-8910 cells proliferation in a dose-dependent and time-dependent manner, there were statistical significance compared with NS group(P < 0.05), and the IC50 was 4.28 μg/mL for 48 h. The cells treated with LAF showed typical morphological change and apoptotic rate increased by FCM in a dose-dependent, and there was notable difference compared with NS group(P < 0.05). Western blot showed that expression of Fas, caspase-8, tBid and Cyto-c proteins were up-regulated after treatment with LAF for 48 h in a concentration dependent. Conclusion: LAF could inhibit HO-8910 cells proliferation and induce apoptosis, which may be through the pathway of death receptor in vitro. | Min Tang Jun Bai Chunyan Chen Yingxia Ning Xiaochun Li Hanzhen He | 2014 | The Chinese-German Journal of Clinical Oncology2014，13，9： | 0 |
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