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| 1 | Recombinant protein subunit vaccine booster following two-dose inactivated vaccines dramatically enhanced anti-RBD responses and neutralizing titers against SARS-CoV-2 and Variants of Concern显示文摘Dear Editor,As of October,2021,SARS-CoV-2 has infected more than 230 million people;promoting roll-out vaccinations could help build herd immunity for the pandemic.However,the waning of antibody in magnitude and decreased protective efficacy in multiple types of vaccines have been reported. | Jingwen Ai Haocheng Zhang Qiran Zhang Yi Zhang Ke Lin Zhangfan Fu Jieyu Song Yuanhan Zhao Mingxiang Fan Hongyu Wang Chao Qiu Yang Zhou Wenhong Zhang | 2022 | Cell Research2022，32，1： | 19 |
| 2 | High-dimensional orbital angular momentum multiplexing nonlinear holography显示文摘Nonlinear holography has been identified as a vital platform for optical multiplexing holography because of the appearance of new optical frequencies.However,due to nonlinear wave coupling in nonlinear optical processes,the nonlinear harmonic field is coupled with the input field,laying a fundamental barrier to independent control of the interacting fields for holography.We propose and experimentally demonstrate high-dimensional orbital angular momentum(OAM)multiplexing nonlinear holography to overcome this problem.By dividing the wavefront of the fundamental wave into different orthogonal OAM channels,multiple OAM and polarization-dependent holographic images in both the fundamental wave and second-harmonic wave have been reconstructed independently in the spatial frequency domain through a type-II second harmonic generation process.Moreover,this method can be easily extended to cascadedχ2 nonlinear optical processes for multiplexing in more wavelength channels,leading to potential applications in multicasting in optical communications,multiwavelength display,multidimensional optical storage,anticounterfeiting,and optical encryption. | Xinyuan Fang Haocheng Yang Wenzhe Yao Tianxin Wang Yong Zhang Min Gu Min Xiaoa | 2021 | Advanced Photonics2021，3，1： | 8 |
| 3 | Kruppel-like factors and vascular wall homeostasis显示文摘 | Yanbo Fan Haocheng Lu Wenying Liang Wenting Hu Jifeng Zhang Y. Eugene Chen | 2017 | Journal of Molecular Cell Biology2017，9，5： | 7 |
| 4 | Conversion of pure Chinese fir plantation to multi-layered mixed plantation enhances the soil aggregate stability by regulating microbial communities in subtropical China显示文摘Background:Soil aggregates are the basic units of soil structure,and their stability is a key indicator of soil quality and capacity to support ecosystem functions.The impacts of various environmental factors on soil aggregates have been widely studied.However,there remains elusive knowledge on the synergistic effects of changing forest stand structure on soil aggregate stability(SAS),particularly in subtropical China where soil erosion remains a critical issue.Methods:We investigated variations in the components of soil humus(HS),including humic acids(HAs),fulvic acids(FAs),and humins(HMs),under pure Chinese fir(Cunninghamia lanceolata)plantation(PP)and multilayered mixed plantation(MP)comprising C.lanceolata,Castanopsis hystrix,and Michelia hedyosperma.The state of soil aggregate stability,was determined by three separate methods,i.e.,dry-sieving,wet-sieving,and the Le Bissonnais.High-throughput sequencing was used to determine the diversity and composition of microbial communities under PP and MP.We then built partial least squares path models(PLS-PM)for assessing the responses of SAS to the variations in soil microorganisms and HS components.Results:The MP stands had significantly greater SAS(P<0.05),higher content of HAs and more rapid organic matter humification within aggregates,than the PP stands.High-throughput sequencing confirmed that the Pielou andα-diversity index values(Chao1 and Shannon)for fungi were all significantly higher under MP than under PP,while no marked difference was found in bacterialα-diversity between the two plantation types.Moreover,there were markedly greater abundance of three bacterial phyla(Verrucomicrobia,Chloroflexi,and Gemmatimonadetes)and three fungal phyla(Ascomycota,Kickxellomycota,and Glomeromycota),and significantly less abundance of two bacterial phyla(Planctomycetes and Firmicutes)and four fungal phyla(Basidiomycota,Mortierellomycota,Mucoromycota,and Rozellomycota)under MP than under PP.The Chloroflexi and Ascomycota phyla appeared to be the primary drivers of soil aggregate distribution.Our findings revealed that the promotion of SAS under MP was mainly driven by increased soil organic matter(SOM)content,which altered bacterial communities and enhanced fungal diversity,thereby increasing HAs content and the rate of organic matter humification.Conclusions:Considering the combined effects of enhanced soil quality,productivity,and relevant economic costs,introducing broadleaved tree species into Chinese fir plantations can be an effective strategy for stabilizing soil structure against erosion in subtropical China.Our study elucidated the controls on variations of SAS in Chinese fir-dominated plantations and demonstrated the benefit of converting pure Chinese fir plantation to multi-layered mixed plantations in increasing soil structural stability and improving site quality. | Guannv Gao Xueman Huang Haocheng Xu Yi Wang Weijun Shen Wen Zhang Jinliu Yan Xiaoyan Su Shushou Liao Yeming You | 2022 | Forest Ecosystems2022，9，6： | 4 |
| 5 | SARS-CoV-2 variants,immune escape,and countermeasures显示文摘Coronavirus disease 2019(COVID-19)has become a global pandemic disease.SARS-CoV-2 variants have aroused great concern and are expected to continue spreading.Although many countries have promoted rollout vaccination,the immune barrier has not yet been fully established,indicating that populations remain susceptible to infection.In this review,we summarize the literature on variants of concern and focus on the changes in their transmissibility,pathogenicity,and resistance to the immunity constructed by current vaccines.Furthermore,we analyzed relationships between variants and breakthrough infections,as well as the paradigm of new variants in countries with high vaccination rates.Terminating transmission,continuing to strengthen variant surveillance,and combining nonpharmaceutical intervention measures and vaccines are necessary to control these variants. | Yi Zhang Haocheng Zhang Wenhong Zhang | 2022 | Frontiers of Medicine2022，16，2： | 2 |
| 6 | COVID-19 Public Opinion and Emotion Monitoring System Based on Time Series Thermal New Word Mining显示文摘With the spread and development of new epidemics,it is of great reference value to identify the changing trends of epidemics in public emotions.We designed and implemented the COVID-19 public opinion monitoring system based on time series thermal new word mining.A new word structure discovery scheme based on the timing explosion of network topics and a Chinese sentiment analysis method for the COVID-19 public opinion environment are proposed.Establish a“Scrapy-Redis-Bloomfilter”distributed crawler framework to collect data.The system can judge the positive and negative emotions of the reviewer based on the comments,and can also reflect the depth of the seven emotions such as Hopeful,Happy,and Depressed.Finally,we improved the sentiment discriminant model of this system and compared the sentiment discriminant error of COVID-19 related comments with the Jiagu deep learning model.The results show that our model has better generalization ability and smaller discriminant error.We designed a large data visualization screen,which can clearly show the trend of public emotions,the proportion of various emotion categories,keywords,hot topics,etc.,and fully and intuitively reflect the development of public opinion. | Yixian Zhang Jieren Cheng Yifan Yang Haocheng Li Xinyi Zheng Xi Chen Boyi Liu Tenglong Ren Naixue Xiong | 2020 | Computers, Materials & Continua2020，，9： | 1 |
| 7 | Flash-assisted doping graphene for ultrafast potassium transport显示文摘Graphene has been widely used for electrical energy storage and its performances could be further improved by heteroatom doping.How to prepare doped graphene efficiently and economically remains a significant challenge.Here,we propose a flash-assisted doping method to produce nitrogen-and sulfur-doped graphene(N-rGO and S-rGO).Using this method,graphene oxide(GO)is reduced to few-layer graphene(rGO)in seconds without the use of reductants,accompanied with a high doping efficiency.Particularly,the as-synthesized N-rGO with a high N content of 12.75 at.%used as potassium-ion battery(KIB)anode exhibits ultrafast K+-transport kinetics and superior K^(+)-storage capability.Quantitative kinetics analysis and theoretical simulation are used to reveal the mechanism of transportation and storage of K^(+)in N-rGO. | Yongzhi Zhang Xianjue Chen Wanglai Cen Wenhao Ren Haocheng Guo Sicheng Wu Yang Xiao Sheng Chen Yong Guo Dan Xiao Chuan Zhao | 2022 | Nano Research2022，15，5： | 1 |
| 8 | DTCC:Multi-level dilated convolution with transformer for weakly-supervised crowd counting显示文摘Crowd counting provides an important foundation for public security and urban management.Due to the existence of small targets and large density variations in crowd images,crowd counting is a challenging task.Mainstream methods usually apply convolution neural networks(CNNs)to regress a density map,which requires annotations of individual persons and counts.Weakly-supervised methods can avoid detailed labeling and only require counts as annotations of images,but existing methods fail to achieve satisfactory performance because a global perspective field and multi-level information are usually ignored.We propose a weakly-supervised method,DTCC,which effectively combines multi-level dilated convolution and transformer methods to realize end-to-end crowd counting.Its main components include a recursive swin transformer and a multi-level dilated convolution regression head.The recursive swin transformer combines a pyramid visual transformer with a fine-tuned recursive pyramid structure to capture deep multi-level crowd features,including global features.The multi-level dilated convolution regression head includes multi-level dilated convolution and a linear regression head for the feature extraction module.This module can capture both low-and high-level features simultaneously to enhance the receptive field.In addition,two regression head fusion mechanisms realize dynamic and mean fusion counting.Experiments on four well-known benchmark crowd counting datasets(UCF_CC_50,ShanghaiTech,UCF_QNRF,and JHU-Crowd++)show that DTCC achieves results superior to other weakly-supervised methods and comparable to fully-supervised methods. | Zhuangzhuang Miao Yong Zhang Yuan Peng Haocheng Peng Baocai Yin | 2023 | Computational Visual Media2023，9，4： | 0 |
| 9 | A Comparison of Co-temporal Vector Magnetograms Obtained with HMI/SDO and SP/Hinode显示文摘Accurate measurement of magnetic fields is very important for understanding the formation and evolution of solar magnetic fields.Currently,there are two types of solar magnetic field measurement instruments:filter-based magnetographs and Stokes polarimeters.The former gives high temporal resolution magnetograms and the latter provides more accurate measurements of magnetic fields.Calibrating the magnetograms obtained by filter-based magnetographs with those obtained by Stokes polarimeters is a good way to combine the advantages of the two types.Our previous studies have shown that,compared to the magnetograms obtained by the Spectro-Polarimeter(SP)on board Hinode,those magnetograms obtained by both the filter-based Solar Magnetic Field Telescope(SMFT)of the Huairou Solar Observing Station and by the filter-based Michelson Doppler Imager(MDI)aboard SOHO have underestimated the flux densities in their magnetograms and systematic center-to-limb variations present in the magnetograms of both instruments.Here,using a sample of 75 vector magnetograms of stable alpha sunspots,we compare the vector magnetograms obtained by the Helioseismic and Magnetic Imager(HMI)aboard Solar Dynamics Observatory(SDO)with co-temporal vector magnetograms acquired by SP/Hinode.Our analysis shows that both the longitudinal and transverse flux densities in the HMI/SDO magnetograms are very close to those in the SP/Hinode magnetograms and the systematic center-to-limb variations in the HMI/SDO magnetograms are very minor.Our study suggests that using a filter-based magnetograph to construct a low spectral resolution Stokes profile,as done by HMI/SDO,can largely remove the disadvantages of the filter-type measurements and yet still possess the advantage of high temporal resolution. | Mei Zhang Haocheng Zhang Chengqing Jiang | 2023 | Research in Astronomy and Astrophysics2023，23，12： | 0 |
| 10 | In vivo precision imaging of vicinal-dithiol-containing proteins by a FRET molecular probe sensitive to protein environment显示文摘We here present a Förster resonance energy transfer(FRET)-based and environment-sensitive fluorescent probe VG-1 for vicinal-dithiol-containing proteins(VDPS).VG-1 uniquely contalns two sites sensitive to the protein environment(SPE)thus it shows weak fluorescence in both blue and green channels(a low FRET efficiency)in solution.After specifically binding with VDPs,its fuorescence in the green channel increases,while that in the blue channel disappears,achieving the specific detection of VDPs.The obvioussignal changes in fluorescence may be attributed to that the increased rigidity of the molecular skeletons causes the enhanced FRET eficiency,The probe also achleved the cell super-resolution imaging of VDPs and the confocal imaging of VDPs in zebrafish. | Haocheng Gong Yanhui Zhang Ying Gao Xinrong Tian Pengzhao Wu Xiaoyu Wei Yuan Guo | 2023 | Chinese Chemical Letters2023，34，12： | 0 |
| 11 | Palladium-Catalyzed Aminomethylation of Nitrodienes and Dienones via Double C-N Bond Activation显示文摘Main observation and conclusion A new strategy for the generation of the active Pd-alkyl species from aminal via C-N bond activation has been established,in which the formation of zwitterionic intermediate through aza-Michael addition of aminal to nitrodienes or dienones is identified as a key step for the activation of the C-N bond.The efficient strategy has enabled a new palladium-catalyzed a-aminomethylation of nitro-dienes and dienones via double C-N bond activation.The scope and versatility of the reaction were demonstrated and a broad range of substrates bearing electron-donating and-withdrawing groups on the aromatic rings were all compatible with this reaction to furnish the desired a-aminomethylated products in moderate to good yields with excellent regioselectivities and E/Z selectivities. | Bangkui Yu Bao Gao Xuexia Zhang Haocheng Zhang Hanmin Huang | 2021 | Chinese Journal of Chemistry2021，39，3： | 0 |
| 12 | Catalytic Benzylation Reactions: From C-H Bond Activation to C-N Bond Activation显示文摘Transition-metal mediated activation of inert chemical bonds is an ongoing topic in homogeneous catalysis.In view of the abundance and accessibility of alkylarenes and benzylamines,the use of them as benzyl source in catalytic benzylation reactions via benzylic C-H and C-N bond activation is highly desirable.Indeed,compared with the traditional approaches with benzyl halide as the substrates,benzylation reactions via C-H and C-N bond cleavage provide more efficient,atom-economic strategies to access myriads of synthetically important molecules.In this account,our group's efforts on catalytic benzylation reactions via directed C-H activation,nondirected C-H activation and C-N bond activation are summarized. | Tianxiao Jiang Hongchi Liu Haocheng Zhang Hanmin Huang | 2021 | Chinese Journal of Chemistry2021，39，5： | 0 |
| 13 | DFDVis:A Visual Analytics System for Understanding the Semantics of Data Flow Diagram显示文摘Data flow diagram(DFD),as a special kind of data,is a design artifact in both requirement analysis and structured analysis in software development.However,rigorous analysis of DFD requires a formal semantics.Formal representation of DFD and its formal semantics will help to reduce inconsistencies and confusion.The logical structure of DFD can be described using formalism of Calculus of Communicating System(CCS).With a finite number of states based on CCS,state space methods will help a lot in analysis and verification of the behavior of the systems.But the number of states of even a relatively small system is often very great that is called state explosion.In this paper,we present a visual system which combines Formal methods and visualization techniques so as to help the researchers to understand and analyze the system described by the DFD regardless of the problem of state explosion. | Hao Xiong Haocheng Zhang Xiaoju Dong Lingxi Meng Wenyang Zhao | 2017 | 国际计算机前沿大会会议论文集2017，，1： | 0 |
| 14 | PBSVis: A Visual System for Studying Behavior Patterns of Pseudo Base Stations显示文摘 | Haocheng Zhang Xiang Tang Chenglu Li Yiming Bian Xiaoju Dong Xin Fan | 2018 | 国际计算机前沿大会会议论文集2018，，1： | 0 |
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