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| 1 | Nat Biotechnol:将人星形胶质细胞重编程为多巴胺能神经元,有助治疗帕金森病显示文摘帕金森病是一种主要影响运动系统的神经退行性疾病。它的特征在于大脑中的多巴胺能神经元(dopaminergic neuron)渐进性丧失。尽管当前的疗法旨在补充多巴胺水平,但是没有一种疗法能够恢复这些丢失的细胞。如今。在一项新的研究中,来自瑞典、奥地利、西班牙和美国的研究人员开发出一种方法:将神经胶质细胞(glialcell)转化为活性的多巴胺能神经元,并且所产生的多巴胺能神经元能够部分恢复帕金森病模式小鼠的运动功能。这项概念验证研究可能为开发出一种治疗这种疾病的新方法铺平道路。 | Pia Rivetti di Val Cervo, Elisa Martín-Montañez, Enrique M Toledo, Gioele La Manno, Sara Padrell Sánchez, Sten Linnarsson Ernest Arenas Roman A Romanov, Christian Pifl Tibor Harkany Roman A Romanov, Giada Spigolon, Débora Masini, Michael Feyder, Tibor Harkany Gilberto Fisone Elisa Martín-Montañez Yi-Han Ng Marius Wernig | 2017 | 现代生物医学进展2017，17，17： | 11 |
| 2 | Chronic aluminum treatment results in aluminum depostis and affects M1 muscarinic receptors in rat brain显示文摘 | Lengyel Z Kasa P | 1996 | Neurobiology Bp1996，4，12： | 1 |
| 3 | Beta-amyloid neurotoxicity is mediated by a glutamated-triggered excitotoxic cascade in rat nucleus basalis显示文摘 | Harkany T Abraham I Timmerman W | 2000 | Eur J Neurosci2000，12，8： | 1 |
| 4 | Retro- pharyngeal abscess in adults: five case reports and re- view of the literature显示文摘 | HARKANI A HASSANI R ZIAD T | 2011 | Scientific World Journal2011，11，： | 1 |
| 5 | Chronic aluminum treatment results in aluminum depostis and affects M1 muscarinic receptors in rat brain 显示文摘 | Harkany T Lengyel Z Kasa P | 1996 | Neurobiology Bp1996，4，： | 1 |
| 6 | Chronic aluminum treatment result in aluminum deposits and affects M1 muscarinic receptors in rat brain 显示文摘 | Harkany T Lengyel Z Kasa P Gluya K | 1996 | Neurobiology1996，4，12： | 1 |
| 7 | Neuroprotective approaches in experimental models of beta-amyloid neurotoxicity: relevance to Alzheimer' s disease显示文摘 | Hortobagyi T Sasvari M | 1999 | Prog Neuropsycho Pharmacol Biol Psychiatry1999，23，： | 1 |
| 8 | Beta-amyloid induced cholinergic denervation correlates with enhanced nitric oxide synthase activity inrat cerebral cortex:reversal by NMDA receptor blocdade 显示文摘 | Omahony S Harkany T Rensind AA | 1998 | Brain Res Ball1998，45，4： | 1 |
| 9 | Neuronal substrates and functional consequences of prenatal cannabis exposure 显示文摘 | Calvigioni D Hurd YL Harkany T | 2014 | Eur Child Adolesc Psychiatry2014，23，10： | 1 |
| 10 | Oral postion-lesion administration of 5-HT1A receptor agonist repinotan hydrochloride (BAYx3702) attenuates NMDA-induced delayed neuronal death in rat magnocellular nucleus basalls 显示文摘 | HARKANY T MULDER J HORVATH K M | 2001 | Neuroscience2001，108，4： | 1 |
| 11 | Mechanisms of beta-amyloid neurotoxicity perspectives of pharmacotherapy显示文摘 | Harkany T Abraham I Konya C | 2000 | Rev Neurosci2000，11，4： | 1 |
| 12 | Action of glucocorticoids on survival of nerve ceils: promoting neurodegeneration or neuroprotection显示文摘 | Abraham IM Harkany T Horvath KM | 2001 | J Neuroendocrinol2001，13，9： | 1 |
| 13 | Retro-pharyngeal abscess in adults:five case reports and re-view of the literature显示文摘 | HARKANI A HASSANI R ZIAD T | 2011 | Scientific World Journal2011，11，： | 1 |
| 14 | Chronic aluminum treatment results in aluminum depostis and affects M1 muscarinic receptors in rat brain 显示文摘 | Harkany Lengyel Z Kasa P | 1996 | Neurobiology Bp1996，4，： | 1 |
| 15 | Beta-amyloid(Phe(SO3H)24)25~35 in rat nucleus basalis induces behavioral dysfunctions, impairs learning and memory and disrupts cortical cholinergic innervation 显示文摘 | Harkany T O'Mahony S Kelly JP | 1998 | Behav Brain Res1998，90，2： | 1 |
| 16 | Chronic aluminum treatment results in aluminum depostis and affects M 1 muscarinic receptors in rat brain显示文摘 | Harkany T Lengyel Z Kasa P | 1996 | Neurobiology (Bp)1996，4，12： | 1 |
| 17 | Mechanisms of beta-amyloid neurotoxicity : perspectives of pharmaco- therapy显示文摘 | Harkany T Abraham I Konya C | 2000 | Rev Neurosci2000，11，4： | 1 |
| 18 | Neuroprotective approaches in experimental models of beta-amyloid neurotoxicity: relevance to Alzheimer′s disease显示文摘 | Hortobagyi T Sasvari M Konya C Penke B Luiten PG | 1999 | Prog Neuropsychopharmacol Biol Psychiatry1999，23，6： | 1 |
| 19 | 17β-Estradiol enhances cortical cholinergic innervation and preserves synaptic density following excitotoxic lesions to the rat nucleus basalis magnocellularis显示文摘 | K.M Horvath W H?rtig R Van der Veen J.N Keijser J Mulder M Ziegert E.A Van der Zee T Harkany P.G.M Luiten | 2002 | Neuroscience2002，，3： | 1 |
| 20 | Chronic ethanol ingestion-induced changes in open-field behavior and oxdative stress in the rat显示文摘 | Harkany T Sasvari M Nyakas C | 1997 | Pharmacol Biochem Behav1997，58，1： | 1 |
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