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	题名	作者	年代	出处	被引量
1	Metastatic pattern in esophageal and gastric cancer:Influenced by site and histology显示文摘BACKGROUND Detailed information on metastatic patterns in of patients with esophageal and gastric cancer is limited.Early recognition of metastases is important to avoid futile locoregional treatments.Furthermore,knowledge on metastatic patterns is necessary for further development of personalized treatment modalities.AIM To gain insight into the metastatic pattern of gastroesophageal cancer.METHODS A nationwide retrospective autopsy study of 3876 patients with adenocarcinoma(AC)or squamous cell carcinoma(SCC)of the esophagus or stomach between 1990 and 2017 was performed.Only patient with metastases were included for analysis.The metastatic pattern was analyzed according to the primary tumor location and histological subtype.RESULTS Metastatic disease was found in 268 esophageal and 331 gastric cancer patients.In esophageal cancer,the most common metastatic locations were liver(56%),distant lymph nodes(53%)and lung(50%).Esophageal AC showed more frequently metastases to the peritoneum and bone compared with esophageal SCC.In gastric cancer,the most common metastatic locations were distant lymph nodes(56%),liver(53%)and peritoneum(51%).Intestinal-type AC of the stomach showed metastases to the liver more frequently,whereas metastases to the bone,female reproductive organs and colorectum were observed more frequently in diffuse-type gastric AC.CONCLUSION This study showed differences in metastatic patterns of patients with esophageal and gastric cancer according to the primary tumor location and histological subtype.	Moniek HP Verstegen Mitchell Harker Carlijn van de Water Jolanda van Dieren Niek Hugen Iris D Nagtegaal Camiel Rosman Rachel S van der Post	2020	World Journal of Gastroenterology2020，26，39：	9
2	A new law of crystal morphology extending the law of Brayals显示文摘	Donnay J D H Harker D	1937	Amer Mineral1937，22，：	1
3	Tactical Scheduling of Rail Operations: The Scan I System 显示文摘	Jovanovic D Harker P T	1991	Transportation Science1991，25，1：	1
4	The use of electrical impedance spectroscopy to assess the physiological condition of kiwifruit显示文摘	Bauchot A D Harker F R Arnold W M	2000	Postharvest Biology and Technology2000，18，1：	1
5	The black bear hunt in New Jersey:Aconstructionist analysis of an intractable conflict显示文摘	Harker D Bates D C	2007	Society andAnimals2007，15，4：	1
6	Optical properties of a region of freshwater influence (the Clyde Sea)显示文摘	Bowers D G Harker G E L Smith P S D	2000	Estuarine Coastal and Shelf Science2000，50，5：	1
7	Absorption spectra of inorganic particles in the Irish Sea and their relevance to remote sensing of chlorophyll显示文摘	Bowers D G G E L Harker and B Stephan	1996	Int J Remote Sens1996，17，12：	1
8	A New Law of Crystal Morphology Extending the Law of Bravais显示文摘	Donnay J D H Harker D	1937	American Mineralogist1937，22，：	1
9	Absorption spectra of inorganic particles in the Irish Sea and their relevance to remote sensing of chlorophyll 显示文摘	BOWERS D G HARKER G E L STEPHAN B	1996	Int J Remote Sens1996，17，：	1
10	Fruit dry matter concentration:a new quality metric for apples显示文摘	PALMER J W HARKER F R TU~'~]'IN D S	2010	Journal of the Science of Food and Agriculture2010，90，15：	1
11	Decision Support Sys-tem for Train Dispatching: an Optimization-based Method-ology显示文摘	JOVANOVIC D HARKER P T	1991	Transportation Research Record1991，1314，：	1
12	Enhanced thrombolytic and antithrombotic potency of a fibrin-targeted plasminogen activator in baboons显示文摘	RUNGE D S HARKER LA BODE C	1996	Circulation1996，94，6：	1
13	Active centres produced in graphite by powdering显示文摘	Harker H Horsley J B Robson D	1971	Carbon1971，9，：	1
14	Optimal pacing of trains in freight railroad: model formulation and solution 显示文摘	KRAAY D HARKER P T CHEN B	1991	Operations Research1991，39，1：	1
15	The Capabilities and Performance Advantages of Market-driven Firms显示文摘	Vorhies D W Harker M Rao C P	1999	European Journal of Marketing1999，33，1112：	1
16	The use of electrical impedance spectroscopy to assess the physiological condition of Kiwifruit显示文摘	Bauchot A D Harker F R Arnold W M	2000	Postharvest Biological Technology2000，18，1：	1
17	A new law of crystal morphology extending the law of Bravais显示文摘	DONNAY J D H HARKER D	1937	Am Mineral1937，22，：	1
18	The capabilities and performance advantages of market - driven firms : an empirical investigation 显示文摘	Vorhies D W Harker M Rao C P	1999	European Journal of Marketing1999，33，：	1
19	Optical properties of a region of freshwater influence (The Clyde Sea)显示文摘	BOWERS D G HARKER G E L SMITH P S D	2000	Estuarine Coastal and Shelf Science2000，50，：	1
20	Multicenter Phase II study of estramustine phosphate plus weekly paclitaxel in patients with androgen-independent prostate carcinoma显示文摘	Vaughn D J Brown A W Jr Harker W G	2004	Cancer2004，100，4：	1

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