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| 1 | Contrast-enhanced intraoperative ultrasonography equipped with late Kupffer-phase image obtained by sonazoid in patients with colorectal liver metastases显示文摘AIM: To find occult metastases during hepatectomy in patients with colorectal cancer liver metastases (CRCLM), contrast-enhanced intraoperative ultrasonography (CE-IOUS) was performed using a new microbubble agent, sonazoid, which provides a parenchyma-specific contrast image based on its accumulation in the Kupffer cells. METHODS: Eight patients with CRCLM underwent CE- IOUS using sonazoid before hepatectomy. The liver was investigated during a late Kupffer-phase imaging, which is a valuable characteristic of sonazoid. RESULTS: CE-IOUS using sonazoid provided the early vascular- and sinusoidal-phase images for 10 min followed by the late Kupffer-phase image up to 30 min after the injection of sonazoid. IOUS did not provide new findings of metastatic lesion in the 8 patients. However, during the late Kupffer-phase image of sonazoid, a metastatic lesion was newly found in two of the 8 patients. These newly detected lesions were removed by an additional hepatectomy and histopathologically diagnosed as a metastasis. CONCLUSION: CE-IOUS using sonazoid can allow surgeons to investigate the whole liver with enough time and to find new metastases intraoperatively. | Hiroshi Nakano Yasuo Ishida Toshiyuki Hatakeyama Kazuma Sakuraba Masahiro Hayashi Osamu Sakurai Kiyoshi Hataya | 2008 | World Journal of Gastroenterology2008，14，20： | 10 |
| 2 | Detection of melon yel- low spot virus (MYSV )by a PCR-microplate hybridization method 显示文摘 | Sato Y Hataya M Hayano-Saito T | 2002 | Kyushu Plant Protection Research2002，48，： | 1 |
| 3 | Molecular genetic studies of HLA-DRB1 alleles in patients with unexplained recurrent abortion in the Japanese population 显示文摘 | Takakuwa K Adachi H Hataya I | 2003 | Hum Reprod2003，18，： | 1 |
| 4 | Occurrence of Chrysanthemum stunt disease in Hokkaido and detection of chrysanthemum stunt viroid by electrophoresis and Hybridization显示文摘 | Hataya T Furuta K | 1997 | Ann Rept Plant Prot North Japan1997，，48： | 1 |
| 5 | Alterations of plasma ghrelin levels in rats with lipopolysaccharide-induced wasting syndrome and effects of ghrelin treatment on the syndrome显示文摘 | Hataya Y Akamizu T Hoeoda H | 2003 | Endicrinology2003，144，12： | 1 |
| 6 | ,Reconstruction of the eyelids and nose after a bum injury using a radial forearm flap显示文摘 | Watanabe T Funuta S Hataya Y | 1997 | Burs1997，23，4： | 1 |
| 7 | Improved power performance for a recessed-gate AlGaN-GaN heterojunction FET with a field-modulating plate显示文摘 | Yasuhiro Okamoto Yuji Ando Koji Hataya | 2004 | IEEE Transactions on Microwave Theory and Techniques2004，52，11： | 1 |
| 8 | Beneficial and Adverse Effects of High-dosage MZR Therapy in the Management of Children with Frequently Relapsing Nephrotic Syndrome显示文摘 | GOTO M LKEDA M HATAYA H | 2006 | Nippon Jinco Gakkai2006，48，4： | 1 |
| 9 | Molecular genetic studies of HLA-DRBI alleles in patients with unexplained recurrent abortion in the Japanese population 显示文摘 | Takakuwa K Adachi H Hataya I | 2003 | Hum Repro2003，18，4： | 1 |
| 10 | Dating of marine terrace sediments by ESR,TL,and OSL methods and their applicabilities显示文摘 | Tanaka K Hataya R Spooner N A | | 0，，： | 1 |
| 11 | Molecular genetic studies of HLA - DRB1 alleles in patients with unexplained recurrent abortion in the Japanese population显示文摘 | Takakuwa K Adachi H Hataya I | 2003 | Hum Rep rod2003，18，4： | 1 |
| 12 | Molecular char- acterization of Hop latent virus and phylogenetic rela- tionships among viruses closely related to carlaviruses 显示文摘 | Hataya T Uchino K Arimoto R | 2000 | Arch Virol2000，145，： | 1 |
| 13 | Thyroid hormone re- placement therapy for primary hypothyroidism leads to significant improvement of renal function in chronic kidney disease patients 显示文摘 | Hataya Y Igarashi S Yamashita T | 2013 | Clin Exp Nephrol2013，17，4： | 1 |
| 14 | Molecular charac- terisation of Hop mosaic virus: Its serological and mo- lecular relationships to hop latent virus显示文摘 | Hataya T Arimoto R Suda N | 2001 | Arch Virol2001，146，： | 1 |
| 15 | Henoch-Schonleinpurpura nephritis with nephrotic state in children : predictors ofpoor outcomes 显示文摘 | Wakaki H Ishikura K Hataya H | 2011 | Pediatr Nephrol2011，26，6： | 1 |
| 16 | 显示文摘 | Hataya Y Akamizu T Takaya K | 2001 | J Clin Endocrinol Metab2001，86，9： | 1 |
| 17 | Dating of marine ter- race sediments by ESR,TL and OSL methods and their appli- cations显示文摘 | Tanaka K Hataya R Spooner N A | 1997 | Quaternary Science Reviews1997，16，35： | 1 |
| 18 | The complete nucleotide sequence and biotype variability of Papaya leaf distortion mosaic virus显示文摘 | Maoka T Hataya T | 2005 | Phytopathology2005，95，2： | 1 |
| 19 | A simple ,rapid method of mucleic acid extraction without tissue homogenization for detection vrioids by hybridization and RT-PCR显示文摘 | NAKAHARA KENJI HATAYA TAISUJI UYEDA ICHIRO | 1999 | Journal of Virological Methods1999，77，： | 1 |
| 20 | Molecular genetic studies of HLA-DRB1 alleles in patients with unexplained recurrent abortion in the Japanese population 显示文摘 | Takakuwa K Adachi H Hataya I | 2003 | Hum Reprod2003，18，： | 1 |
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