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| 1 | BTLA marks a less- differentiated tumor-infiltrating lymphocyte subset in melanoma with enhanced survival properties显示文摘 | Haymaker CL Wu RC Ritthipichai K el al | 2015 | Oncoimmunnlo''2015，4，10： | 1 |
| 2 | Supersymmetry in quantum mechanics 显示文摘 | Haymaker R W Rau A R P | 1986 | Am J Phys1986，54，： | 1 |
| 3 | Tumor-Infiltrating Lymphocyte Therapy for Melanoma: Rationale and Issues for Further Clinical Development显示文摘 | Geok Choo Sim Jessica Chacon Cara Haymaker Krit Ritthipichai Manish Singh Patrick Hwu Laszlo Radvanyi | 2014 | BioDrugs2014，，： | 1 |
| 4 | Mucormycosis of the central nervous system:a report of three cases显示文摘 | Gregory JE Golden A Haymaker W | 1943 | Bull Johns Hopkins Hosp1943，，： | 1 |
| 5 | Fluorinated 1,2,3-triazolines显示文摘 | Carpenter Wayne R Haymaker Ann Moore Donald W | | 0，，03： | 1 |
| 6 | Mucormycosis of the central nervous system: a report of three cases 显示文摘 | Gregory JE Golden A Haymaker W | 1943 | Bull Johns Hopkins Hosp1943，73，： | 1 |
| 7 | Heat stroke; aclinico-pathologic study of 125 fatal cases 显示文摘 | Malamud N Haymaker W Custer R P | 1946 | Mil Surg1946，99，5： | 1 |
| 8 | Relationships between Project Complexity and Communication显示文摘 | Reid Robert Senescu Guillermo Aranda-Mena John Riker Haymaker | 2013 | Journal of Management in Engineering2013，，2： | 1 |
| 9 | Heat stroke, a elinieo- pathologic study of 125 fatal cases 显示文摘 | Malamud N Haymaker W Custer RP | 1946 | Mil Surg1946，99，5： | 1 |
| 10 | PD-1 and BTLA and CD8+ T-cell 'exhaustion' in cancer: 'Exercising' an alternative viewpoint显示文摘 | Haymaker C Wu R Bernatchez C | 2012 | Oncoimmunology2012，1，5： | 1 |
| 11 | Fetal expo- sure to high-avidity TCR ligand enhances expansion of peripheral T regulatory cells 显示文摘 | Yu P Haymaker C L Divekar R D | 2008 | Journal of Immunolo- gy2008，181，： | 1 |
| 12 | Filter mediated design:generating coherence in collaborative design显示文摘 | Haymaker J Keel P Ackermann E Porter W | 2000 | Design Studies2000，21，2： | 1 |
| 13 | Variational-methods for composite-oper- ators显示文摘 | Haymaker R W | 1991 | Rivista del Nuovo Cimento1991，14，8： | 1 |
| 14 | Bulgingof the mesh after laparoscopic repair of ventral and incisional her-nias显示文摘 | Schoenmaeckers KJ Wassenaar EB Haymakers JT | 2010 | JSLS2010，14，4： | 1 |
| 15 | Age - associated oxygen damage and mutation in minchondrial DNA in human hearts 显示文摘 | Haymakers M Hattorit S | 1992 | Biochem Biophys Roes commun1992，189，2： | 1 |
| 16 | Colloid cyst of the third ventricle; a clinical study of 54 cases in the light of previous publications显示文摘 | Yenermen MH Bowerman CI Haymaker W | 1958 | Acta Neuroveg (Wien)1958，17，： | 1 |
| 17 | Integrative genomic and transcriptomic profiling of pulmonary sarcomatoid carcinoma identifies molecular subtypes associated with distinct immune features and clinical outcomes显示文摘Background:Pulmonary sarcomatoid carcinoma(PSC)is a rare and aggressive subtype of non-small cell lung cancer(NSCLC),characterized by the presence of epithelial and sarcoma-like components.The molecular and immune landscape of PSC has not been well defined.Methods:Multiomics profiling of 21 pairs of PSCs with matched normal lung tissues was performed through targeted high-depth DNA panel,whole-exome,and RNA sequencing.We describe molecular and immune features that define subgroups of PSC with disparate genomic and immunogenic features as well as distinct clinical outcomes.Results:In total,27 canonical cancer gene mutations were identified,with TP53 the most frequently mutated gene,followed by KRAS.Interestingly,most TP53 and KRAS mutations were earlier genomic events mapped to the trunks of the tumors,suggesting branching evolution in most PSC tumors.We identified two distinct molecular subtypes of PSC,driven primarily by immune infiltration and signaling.The Immune High(IM-H)subtype was associated with superior survival,highlighting the impact of immune infiltration on the biological and clinical features of localized PSCs.Conclusions:We provided detailed insight into the mutational landscape of PSC and identified two molecular subtypes associated with prognosis.IM-H tumors were associated with favorable recurrence-free survival and overall survival,highlighting the importance of tumor immune infiltration in the biological and clinical features of PSCs. | Sahil Seth Runzhe Chen Yang Liu Junya Fujimoto Lingzhi Hong Alexandre Reuben Susan Varghese Carmen Behrens Tina McDowell Luisa Solis Soto Cara Haymaker Annikka Weissferdt Neda Kalhor Jia Wu Xiuning Le Natalie I Vokes Chao Cheng John V.Heymach Don L.Gibbons P.Andrew Futreal Ignacio IWistuba Humam Kadara Jianhua Zhang Cesar Moran Jianjun Zhang | 2024 | Cancer Innovation2024，3，3： | 0 |
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