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| 1 | 胃癌预防亚太地区共识指南显示文摘背景与目的:胃癌是亚太地区的主要健康负担之一,但对其预防策略尚缺乏共识。本共识会议旨在评价预防胃癌的策略。方法:多学科专家组应用德尔菲(Delphi)法制订共识条文,提呈相关数据,对证据等级、推荐强度以及共识水平予以分级。结果:幽门螺杆菌(H.pylori)感染是非贲门胃腺癌必要但非充分的致病因子。盐的高摄入与胃癌强烈相关。新鲜果蔬对胃癌具有预防作用,但维生素和其他饮食补充并不能预防胃癌。H.pylori感染中的宿主-细菌相互作用导致不同类型的胃炎和胃酸分泌,从而决定疾病结局。胃癌阳性家族史是一个重要的危险因素。低血清胃蛋白酶原反映胃萎缩程度,可作为检出胃癌高危人群的标志物。H.pylori筛查和治疗被推荐作为减少高危人群胃癌危险性的一种策略,该策略在萎缩性胃炎发生前实施最为有效,但并不排除对胃癌高危人群的内镜监测。对胃癌低危人群不推荐行H.pylori筛查。H.pylori感染的一线治疗应遵循国家治疗指南。结论:高危人群中H.pylori筛查和根除策略可能会减少胃癌的发生率,本共识根据现有证据予以推荐。 | Kwong Ming Fock Nick Talley Paul Moayyedi Richard Hunt Takeshi Azuma Kentaro Sugano Shu Dong Xiao Shiu Kum Lam Khean Lee Goh Tsutomu Chiba Naomi Uemura Jae G Kim Nayoung Kim Tiing Leong Ang Varocha Mahachai Hazel Mitchell Abdul Aziz Rani Jyh Ming Liou Ratha-korn Vilaichone Jose Sollanor 钱本余 | 2008 | 胃肠病学2008，13，4： | 37 |
| 2 | Copper(Ⅱ) - bisoxazoline catalyzed asymmetric 1,3 - dipolar cycloaddition reactions of nitrones with electron -rich alkenes 显示文摘 | Jensen K B Hazell R G Jφrgensen K A | 1999 | J Org Chem1999，64，： | 1 |
| 3 | Maintenance chemotherapyin limited small cell lung cancer:a randomised controlled clinicaltrial显示文摘 | Byrne MJ van Hazel G Trotter J | 1989 | Br J Cancer1989，60，3： | 1 |
| 4 | Lead neuro toxicity in children: is prenatal exposure more important than postnatal exposure? 显示文摘 | Ronchetti R Van Hazel P Schoeters G | 2006 | Acta Paediatr Suppl2006，95，453： | 1 |
| 5 | Catalytic enantioselective inverse -electron demand 1,3 -dipolar cycloaddition reactions of nitrones with alkenes 显示文摘 | Simonsen K B Bayon P Hazell R G | 1999 | J Am Chem Soc1999，121，： | 1 |
| 6 | Enantioselective a-amination of ketones mediated by chiral nitridomanganese (V) complexes using ammonia as the terminal nitrogen source 显示文摘 | Svenstrup N Boevig A Hazell R G | 1999 | J Chem Soc Perkin Trans1999，，： | 1 |
| 7 | Single factors direct the differentiation of stem cells from the fetal and adult central nervous system显示文摘 | JOHN K K HAZEL T G MULLER T | 1996 | Genes Dev1996，10，： | 1 |
| 8 | Lead neurotoxicity in children:Is prenatal exposure more important than postnatal exposure显示文摘 | Ronchetti R van den Hazel P Schoeters G | 2006 | Acta Paediatr2006，10，95： | 1 |
| 9 | Localisation of GPR30, a novel G protein-coupled oestrogen receptor, suggests multiple functions in rodent brain and peripheral tissues显示文摘 | Hazell G Yao S Roper J | 2009 | J Endo- crinol2009，202，2： | 1 |
| 10 | Determination of trazodone and its metabolite,1-mChlorophenyl-piperazine,in human plasma and red blood cell samples by HPLC显示文摘 | VATASSERY G T HOLDEN L A HAZEL D K | 1997 | Clinical Biochemistry1997，30，2： | 1 |
| 11 | Single factors defect the differentiation of stem cells from the fetal and adult central nervous system 显示文摘 | Hazel T G Muller T | 1996 | Genes Dev1996，10，： | 1 |
| 12 | Hydrothermal Synthesis of Lithium Zinc Phosphates Structural Investiga-tion of Twinned a-Li4Zn(PO4)2 and a High Temperature Polymorph β-Li4Zn(PO4)2显示文摘 | Jensen T R Hazell R G Christensen A N | 2002 | Journal of Solid State Chemistry2002，，166： | 1 |
| 13 | Quadruplex DNA: Sequence, topology and struc- ture显示文摘 | BURGE S PARKINSON G N HAZEL P | 2006 | Nucleic Acids Research2006，34，19： | 1 |
| 14 | Synthesis of carboxymethyl-(3-cyclodextrin conjugated magnetic nano-adsorbent for removal of methylene blue显示文摘 | Badruddoza A Z M Hazel G S S Hidajat K | 2010 | Colloids Surf A: Physicochem Eng Aspects2010，367，13： | 1 |
| 15 | Synthesis of carboxymethyl-β-eyclodextrin conjugated magnetie nano-adsorbent for removal of methylene blue显示文摘 | Badruddoza A Z M Hazel G S S Hidajat K | 2010 | Colloid Surface A Eng Aspects2010，367，： | 1 |
| 16 | Mechanisms of neuronal cell death in Wernicke's encephalopathy显示文摘 | HAZELL A S TODD K G BUTTERWORTH R F | 1998 | Metab Brain Dis1998，13，2： | 1 |
| 17 | Lead neurotoxicity in children is prenatal exposure more important than postnatal exposure 显示文摘 | Ronchetti R van den Hazel P Schoeters G | 2006 | Acta Paediatr Suppl2006，95，453： | 1 |
| 18 | Two-photon absorption and the design of two- photon dyes 显示文摘 | Mitosz Pawlicki Hazel A Collins Robert G Denning | 2009 | Angew Chem Int Ed2009，48，： | 1 |
| 19 | Gemcitabine with a specific comformal 3D5-FU radiochemotherapy technique is safe and effective in the definitive management of loally adwanced pancreatic cancer显示文摘 | Goldstein D Van Hazel G Walpole E et al | 2007 | Br J Cancer2007，97，4： | 1 |
| 20 | A novel layered templated lithium zinc phosphate prepared by an unusual solution mediated technique显示文摘 | Jensen T R Hazell R G | | 0，，： | 1 |
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