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44篇 您的检索式：作者名="Hecker W"

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	题名	作者	年代	出处	被引量
1	Response evaluation of chemotherapy in metastatic colorectal cancer by contrast enhanced ultrasound显示文摘AIM:To evaluate whether contrast enhanced ultrasound(CEUS) might also be used for response prediction and early response evaluation in patients receiving bevacizumab based chemotherapy for metastasized colorectal cancer.METHODS:Thirty consecutive patients with non primary resectable liver metastases from colorectal cancer underwent CEUS before treatment(CEUS date 1) and before the second(CEUS date 2) and fourth(CEUS date 3) cycle of bevacizumab based chemotherapy.Three parameters [PEAK,Time to peak(TTP) and RISE RATE]were correlated with radiological response.RESULTS:For neoadjuvant purpose a reduction of tumour mass was required to assume clinical response.Based on these response criteria there was a significant(P < 0.001) correlation in TTP between metastases of responders(9.08 s) and non-responders(14.76 s) archived on CEUS date 1.By calculating a standardized quotient(metastases divided by normal liver tissue) we were able to define a cut off,predicting response with a sensitivity of 92.3 % and a specificity of 100 %.To reflect a palliative intention only those patients with progressive disease were classified as non-responders.In this stetting TTP was also significantly(P < 0.01) different between responders and non-responders.In contrast,Peak and Rise rate did not show any significant difference between responder and non-responder.CONCLUSION:CEUS might serve as a surrogate marker to predict treatment response in patients with metastasized colorectal cancer who receive antiangiogenic therapy.	Ramin Schirin-Sokhan Ron Winograd Christoph Roderburg Jhenee Bubenzer Nicole Cabral do ó Dorothee Guggenberger Hartmut Hecker Christian Trautwein Jens J W Tischendorf	2012	World Journal of Gastroenterology2012，18，6：	16
2	Irritant phor- bol derivatives from four Jatropha species 显示文摘	ADOLF W OPFERKUCH H J HECKER E	1984	Phytochem- istry1984，23，1：	1
3	Responses of the medaka HPG axis PCR array and reproduction to prochloraz and ketoeonazole 显示文摘	Zhang X W Hecker M Jones P D	2008	Environmental Science and Technology2008，42，17：	1
4	Real-time PCR ar- ray to study effects of chemicals on the Hypothalamic- Pituitary-Gonadal axis of the Japanese medaka 显示文摘	Zhang X Hecker M Park J W	2008	A- quatic Toxicology2008，88，3：	1
5	Low Temperature Char Oxidation Kinetics: Effect of Preparation Method显示文摘	McDonald K M Hyde W D Hecker W C	1992	Fuel1992，71，3：	1
6	Catalysis and Automotive Pollution Control显示文摘	Hecker W C Breneman R B	1986	Studies in Surface Science and Catalysis1986，30，：	1
7	Reduction of NO by H2 over silica - supported rhodium: Infrared and kinetic studies 显示文摘	Hecker W C Bell A T	1985	J Catal1985，，92：	1
8	Reduction of NO by CO over sill ca-supported rhodium: infrared and kinetic stud- ies显示文摘	Hecker W C Bell A T	1983	Journal of Catalysis1983，84，1：	1
9	Mid Terra Course after Pediatric Right Ventricular Outflow Tract Reconstruction:a Comparison of Homografts,Porcine Xenografts and Contegras显示文摘	Boethig D Thies W R Hecker H	2005	Eur J Cardiothorac Surg2005，27，1：	1
10	Irritant phorbol derivatives from fourJatropha species 显示文摘	Adolf W Opferkuch H J Hecker E	1988	Phytochemistry1988，23，1：	1
11	Reduction of NO by CO over sili- ca-supported rhodium: infrared and kinetic studies 显示文摘	Hecker W Bbll A T	1983	J Catal1983，84，1：	1
12	Capabihties, Proactive CSR and Financial Performance in SMEs :Empirical Evidence from An Australian Manufacturing Industy Sector 显示文摘	TOYUGSA N A O' DONOHUE W HECKER R	2012	Journal of Business Ethics2012，10，9：	1
13	Reduction of NO by CO over sili- ca-supported rhodium: infrared and kinetic studies显示文摘	HECKER W C BELL A T	1983	Journal of Catalysis1983，84，1：	1
14	Proactive CSR:An Empirical Analysis of the Role of Its Economic,Social and Environmental Dimensions on the Association between Capabilities and Performance显示文摘	TORUGSA N A O'DONOHUE W HECKER R	2013	Journal of Business Ethics2013，115，2：	1
15	Reduction of NO by CO over silica-supported rhodium: Infrared and kinetic studies 显示文摘	Hecker W C Bell A T	1983	Journal of Catalysis1983，84，1：	1
16	Irritant phorbol deriva- tives from four Jatropha species 显示文摘	Adolf W Opferkuch H J Hecker E	1984	Phytoehemistry1984，23，1：	1
17	Reduction of NO by CO over silicasupported rhodium: infrared and kinetic studies显示文摘	Hecker W Bell A T	1983	J Catal1983，84，20：	1
18	Effects of sulfate species on V2O5/Ti O2SCR catalysts in coal and biomassfired systems显示文摘	Guo X Y Bartholomew C Hecker W	2009	Applied Catalysis B:Environmental2009，92，1：	1
19	Effects of sulfate species on V2O5/TiO2 SCR catalysts in coal and biomass-fired systems 显示文摘	Guo X Y Bartholomew C Hecker W Baxter L L	2009	Applied Catalysis B: Environmental2009，92，：	1
20	Heat-shock and general stress response in Bacillus subtilis显示文摘	Hecker M Schumann W Volker U	1996	Molecular Microbiology1996，19，3：	1

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