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| 1 | The δ^(18)O variation of a stalagmite from Qixing Cave,Guizhou Province and indi-cated climate change during the Holocene显示文摘A stalagmite from Qixing Cave, Guizhou Province was dated with the TIMS U-series method and its oxygen isotope composition was analyzed. On the basis of the ages and the variations of the δ18O of the stalagmite, the climate change of the last 7.7 ka has been reconstructed in this area: 7.7-5.8 ka, summer monsoon maximum period; 5.8-3.8 ka summer monsoon weakening period; 3.8-0.15 ka, weakened summer monsoon and high amplitude climate fluctuations period. We put forward that the increasing trend of δ18O of the stalagmite reflected not only the weakening of the summer monsoon, which was caused by the decreasing of solar radiation in the Northern Hemisphere, but also the possibly decreasing contribution of the southwest monsoon to the rainfall of this area. These results are consistent with the output of the numerical climate-model modeling. The high amplitude fluctuation of the δ18O may imply the quick shift of the contributions of different moisture sources to the precipitation in this area. | CAI Yanjun, ZHANG Meiliang, PENG Zicheng, LIN Yushi, AN Zhisheng, ZHANG Zhaofeng & CAO YunningState Key Laboratory of Loess and Quaternary Geology, Institute of Earth Environment, Chinese Academy of Sciences, Xi’an 710054, China Karst Dynamics Laboratory, Ministry of Land and Resources, Guilin 541003, China Department of Earth and Space Science, University of Science & Technology of China, Hefei 230023, China | 2001 | Chinese Science Bulletin2001，46，22： | 18 |
| 2 | Blocking effects of siRNA on VEGF expression in human colorectal cancer cells显示文摘AIM:To investigate the expression of vascular endothelial cell growth factor (VEGF) and its receptors Fmslike tyrosine kinase 1 (FLT-1) and fetal liver kinase 1 (FLK-1) in colorectal carcinoma (CRC),and the blocking effects of small interfering RNAs (siRNAs) on VEGF expression in human colorectal cancer HCT116 cells.METHODS:Immunohistochemical staining for VEGF,FLT-1 and FLK-1 proteins was performed in 82 cases of CRC and 14 normal colorectal mucosae.A siRNA targeting VEGF was synthesized and transfected into HCT116 cells using lipofectamine 2000.Immunocytochemical staining and Western blotting analyses were performed to detect the expression of VEGF protein.The suppressive effect of the siRNA on cell proliferation was detected using the 3-(4,5-dimethylthiazol-2-yl)2,5-diphenyltertrazolium bromide (MTT) assay.Cellular apoptosis was detected using flow cytometry (FCM).RESULTS:The expression of VEGF,FLT-1 and FLK-1 in tumor tissues was significantly higher than that in normal tissues (P=0.008,P=0.000,P=0.000).The expression of VEGF was positively correlated with both lymph node metastasis and clinical stage (P=0.009 and P=0.025,respectively).Immunocytochemistry showed that the expression of VEGF was weakly positive and Western blotting indicated a significant reduction in VEGF-siRNA cell protein levels.VEGF-siRNA cell growth inhibition was assessed by the MTT assay,and the tumor cell proliferation rate was significantly different at 24,48,and 72 h after transfection.FCM results showed that the VEGF-siRNA group had an apparent aneuploid peak.CONCLUSION:VEGF,FLT-1 and FLK-1 are associated with colorectal carcinogenesis.siRNA silencing of the VEGF gene suppresses proliferation,and induces apoptosis in HCT116 cells.The results suggest that VEGF may be a new gene therapy target for colorectal cancer. | Yu Yin,Li-Yu Cao,Wen-Qing Wu,Hao Li,Yan Jiang,Hong-Fu Zhang,Department of Pathology,Anhui Medical University,Hefei 230032,Anhui Province,China Wen-Qing Wu,Department of Pathology,Anhui Provincial Hospital,Hefei 230001,Anhui Province,China | 2010 | World Journal of Gastroenterology2010，16，9： | 9 |
| 3 | Teracluster LSSC-II--Its designing principles and applications in large scale numerical simulations显示文摘The teracluster LSSC-II installed at the State Key Laboratory of Scientific and Engineering Computing, Chinese Academy of Sciences is one of the most powerful PC clusters in China. It has a peek performance of 2Tflops. With a Linpack performance of 1.04Tflops, it is ranked at the 43rd place in the 20th TOP500 List (November 2002), 51st place in the 21st TOP500 List (June 2003), and the 82nd place in the 22nd TOP500 List (November 2003) with a new Linpack performance of 1.3Tflops. In this paper, we present some design principles of this cluster, as well as its applications in some large-scale numerical simulations. | ZHANG Linbo, CHEN Shiyi, LI Xinliang, CAO Jianwen, ZHANG Wensheng & GONG XingaoState Key Laboratory of Scientific and Engineering Computing, Academy of Mathematics and System Sciences, Chinese Academy of Sciences, Beijing 100080, China Department of Mechanical Engineering, The Johns Hopkins University and Center for Computational Science and Engineering, Peking University, Beijing 100875, China Institute of Mechanics, Chinese Academy of Sciences, Beijing 100080, China Parallel Computing Laboratory, Institute of Software, Chinese Academy of Sciences, Beijing 100080, China Academy of Mathematics and System Sciences, Chinese Academy of Sciences, Beijing 100080, China Surface Physics Laboratory (National Key Laboratory), Fudan University, Shanghai 200433 Institute of Solid State Physics, Chinese Academy of Sciences, Hefei 230031, China | 2004 | Science China Mathematics2004，47，z1： | 8 |
| 4 | Dietary Methionine Affect Meat Qulity and Myostatin Gene Exon 1 Region Methylation in Skeletal Muscle Tissues of Broilers显示文摘Dietary amino acids imbalance will result in stunted broiler performance and deteriorated meat quality, which are involved in various biochemical cycles in vivo. In this study, the effects of dietary methionine on meat quality and methylation of myostatin exon 1 were investigated. Drip loss of the broilers fed with diet of high methionine levels (0.2%) increased from (6.3 ± 0.1)% (control group) to (10.1 ± 1.0)%, and the muscle shearing force increased from (22.8 ± 1.9) N (control group) to (26.3 ± 2.3) N. Moreover, many CpG sites were found at the myostatin exon 1 region (nucleotides 2 360-2 540 bp). To further understand the regulation of broiler myostatin expression, the methylation status of broiler myostatin exon 1 and its mRNA expression were analyzed. At the myostatin exon 1 region where CG enriches (nucleotides 2 360-2 540 bp), the percentages of methylation were 46 and 84% in low Met and high Met content groups after 55-d feeding, respectively. In skeletal muscle tissues, the exon 1 hypermethylation status of myostatin gene was found to be negatively correlated with the gene expression. These results suggested that methylation of this gene is a dynamic process, which plays a dominant role in regulating gene expression for development of individuals. | LIU Guo-qing , ZONG Kai, ZHANG Li-li and CAO Shu-qing School of Biotechnology and Food Engineering, Hefei University of Technology, Hefei 230009, P.R.China | 2010 | Agricultural Sciences in China2010，9，9： | 6 |
| 5 | Metallogenic geochemistry of Sb-mineralization in southern margin of North China platform显示文摘1 Geological setting THE Sb mineralization zone in the south margin of North China platform is located in the transitional edgeof North China plate and Yangtze plate, belonging to Qinling fold system, whose tectonic line is inNWW-SEE direction regionally. Because of the huge compression caused by the collision of the twoplates, the rocks undergone strong deformation and metamorphism have very complicated structures. Theregional deep fault-Shuanghuaishu fault-controls Sb-mineralization zone belt, and all the Sb-oredeposits or mineralized spots appear alone at the very southern margin of the fault. The lithostragraphirunits in the mineralized zone are relatively simple, mainly composed of Jiebei Group (Pt2J2) of QinglingFormation (with middle-high metamorphsim) and the upper Triassic system (with little metamorphism). | YANG Xiaoyong~1, YANG Xueming~1, ZHANG Jianjun~2, CAO Gaoshe~2 and ZHANG Zhengwei~2 1. Department of Earth and Space Sciences, University of Science and Technlogy of China, Hefei 230026, China 2. Institute of Geology, Henan Bureau of Geology and Mineral Resources, Zhengzhou 450053, China | 1999 | Chinese Science Bulletin1999，44，S2： | 6 |
| 6 | Influence of precipitation on the Portevin-Le Chatelier effect in Al-Mg alloys显示文摘In the alloy with solute content higher than the limiting solubility,the solute atoms that have failed to dissolve will precipitate from the solid solution and form precipitations.In this study, the Portevin-Le Chatelier(PLC) effects in annealed 5456 and 5052 aluminum alloys with different precipitation contents have been investigated under different applied strain rates.The results suggest that precipitations have significant effect on the PLC effect and the more the precipitations are, the greater the ... | Qi Hu,~(a))Qingchuan Zhang,~(b)) Shihua Fu,Pengtao Cao,and Ming Gong CAS Key Laboratory of Mechanical Behavior and Design of Materials,University of Science and Technology of China,Hefei 230027,China | 2011 | Theoretical & Applied Mechanics Letters2011，1，1： | 3 |
| 7 | Microstructure and thermal stability behavior of a rapidly solidified Al-Ti-Fe-Cr alloy显示文摘A rapidly solidified Al-2.5Ti-2.5Fe-2.5Cr (mass fraction in %) alloy was prepared by melt spinning. Asquenched and as-annealed microstructures were studied by X-ray diffractometry (XRD), transmission electron microscopy (TEM), high-resolution transmission electron microscopy (HREM) and energy dispersive spectrum (EDS) analysis.The microhardness of the alloy at different annealing temperatures was measured. The results obtained indicate that the microhardness of the rapidly solidified Al-2.5Ti-2.5Fe-2.5Cr alloy does not vary with different annealing temperatures.The as-quenched microstructure of the alloy includes two kinds of dispersed primary phases: Al3Ti and Al13(Cr, Fe)2. After annealing at 400 ℃ for 10 h, the stable phase Al13Fe4 appears in the microstructure. | CHEN Yiqing, CAO Qingping, and SU YongSchool of Materials Science and Engineering, Hefei University of Technology, Hefei 230009, China | 2002 | Rare Metals2002，21，3： | 3 |
| 8 | Quenching rate constants for metastable molecule PC1(b^1∑^+,v' = 0)显示文摘IN this decade, great attention has been paid to PCl(b1∑+) because of its potential importance in chemical laser. Coxon et al. studied the reaction of Ar(3Po,2) with PCl3 and observed two band systems of PCl(A3Ⅱ→X3∑-) and (b1∑+→X3∑-). Beielefeld et al. and Setser et al. measured the radiative lifetime of PCl(b1∑+) and its quenching rate constants for some small molecule quenchers. Recently, we have prepared a clean source of PCl(b,υ′= O) in | LIU Chuanpu, ZOU Shengli, GUO Jingzhong, GU Yueshu, CAO Dezhao and CHU Yannan Department of Chemistry, Shandong University, Jinan 250100, China Anhui Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Hefei 230031, China | 1997 | Chinese Science Bulletin1997，42，17： | 2 |
| 9 | Electrostatic Discharge Effects on the High-voltage Solar Array显示文摘A certain number of charges are deposited on the surface of high-voltage solar array because of effects of space plasma,high-energy charged particles,and solar illumination,hence the surface is charged.Phenomena of electrostatic discharge(ESD) occur on the surface when the deposited charges exceed a threshold amount.In this paper,the mechanism of this ESD is discussed.The ground simulation experiment of the ESD using spacecraft material under surface charging is described,and a novel ESD protecting method for high-voltage solar array,i.e.an active protecting method based on the local strong electric field array is proposed.The results show that the reversal potential gradient field between the cover surface and the substrate materials of high-voltage solar array is a triggering factor for the ESD on the array.The threshold voltage for the ESD occurring on the surface is about 500 V.The charged particles could be deflected using the electric field active protecting method,and hence the ESD on the surface is avoided even when the voltage on the conductor array increases to a certain value.These results pave the way for further developing the protecting measures for high-voltage solar arrays. | YUAN Qingyun SUN Yongwei CAO Hefei LIU Cunli | 2013 | 高电压技术2013，39，10： | 2 |
| 10 | Microstructure and optical properties of nano Ag-ITO films显示文摘Nano Ag-ITO films with Ag volume fraction of 0.3%-1.0% were prepared by radio-frequency magnetron co-sputtering and analyzed by X-ray diffraction,scanning electron microscopy and ultraviolet-visible spectroscopy.Microstructure analysis shows that the films are composed of polycrystalline ITO matrix embedded with Ag nanoparticles with a mean size of 60-100 nm.Transmissivity spectra of Ag-ITO films indicate that the visible light transmissivity of the films decreases with increasing the Ag fraction.The transmissivity of the annealed films is higher than that of the as-deposited films.The volume 0.3% Ag-ITO films have the highest light reflectance.The annealed films exhibit lower light absorptance than as-deposited films.A surface plasmon resonance(SPR) peak of volume 0.3% Ag-ITO films is located around 510 nm.Compared with the annealed ITO film,the annealed volume 0.3% Ag-ITO film shows 10% higher reflectivity,while its transmittance is almost the same as that of the annealed ITO film,indicating its potential application in new-type transflective displays. | XIAO Lei1,3,CAO ChunBin2,3,SONG XuePing1,3,MENG FanMing1,3 & SUN ZhaoQi1,3 1 School of Physics and Material Science,Anhui University,Hefei 230039,China 2 School of Sciences,Anhui Agricultural University,Hefei 230036,China 3 Key Laboratory of Opto-Electronic Information Acquisition and Manipulation,Ministry of Education,Hefei 230039,China | 2010 | Science China(Technological Sciences)2010，53，5： | 1 |
| 11 | Experimental investigations on validity of moving chemical reaction boundary equation for the strong acid——weak base system with an excess of potassium chloride显示文摘A moving chemical reaction boundary (MCRB) is formed by the weak alkali NH3*H2O and strong acid HCl with an excess of potassium chloride as background electrolyte. The experimental results are compared with the predictions in accordance with the moving chemical reaction boundary equation (MCRBE). If the MCRB is cathodic, the experimental results are in agreement with the predictions by the MCRBE. However, if the MCRB is anodic, the experimental results significantly deviate from the predictions of the MCRBE. A corrected MCRB equation is proposed for such conditions. The findings are evidently different from those in our early reports(J. Chromatogr. A, 891 (2000): 337~347; 907 (2001): 347~352; 922 (2001) 283~393). This study is of obvious benefit to capillary electrophoresis and isoelectric focusing. | ZHOU Shulin, CAO Chengxi, QIAN Yitai, HE Youzhao, YANG Li, Qu Qishu and CHEN Wenkui(1. School of Life Science and Technology, Shanghai Jiaotong University, Shanghai 200030, China 2. Department of Chemistry, University of Science and Technology of China, Hefei 230026, China 3. Institute of Allergy Reserch, Wannan Medical College, Wuhu 241001, China) | 2002 | Progress in Natural Science:Materials International2002，12，9： | 0 |
| 12 | PROPERTIES AND SYNTHESIS OF NEW SUPPORTS FOR IMMOBILIZATION OF ENZYMES BY COPOLYMERIZATION OF VINYLENE CARBONATE AND METHACRYLIC ACID显示文摘Methacrylic acid first was neutralized with an aqueous solution of NaOH to pH=6.0~7.0, vinylene carbonate(VCA) was added to the solution, then monomers were copolymerized in paraffin oil by means of reverse-phase suspensionpolymerization and hydrophilic copolymeric supports were prepared. The properties of the supports were determined usingtrypsin and results show that the amount of enzymes coupled to the supports and the specific activity of immobilized trypsinare related to the content of VCA structure units, reaction time and concentration of enzyme solution, etc. | Lun-han Ding Yue Li Yan Jiang Zhe Cao Jia-xian Huang Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei 230026, China Department of Chemistry, Nankai University, Tianjin 300071, China | 2000 | Chinese Journal of Polymer Science2000，18，4： | 0 |
| 13 | HREELS Studies on Adsorption and Decomposition of ^(15)NO on Mo(100)-c(2×2)N Surface显示文摘High resolution electron energy loss spectroscopy (HREELS) has been used to investigate the adsorPtion and decomposition of 15NO on the Mo(100)-c(2×2)14N surface. At 140K, the 15NO molecu1e could adsorb associatively on atop sites of the Mo and l4N atoms in the nitride layers. On the other hand, a small amount of dissociatCd 15NO also exists. The dissociation of surface nitric oxides species at elevated temperatures caused the oxidation of the surface Mo. | Jun Fa ZHU Shu Xian ZHUANG Jian Chang GUO Run Sheng ZHAI Yu Ming CAO Xin He BAO(Department of Chemical Physics, University of Science and Technology of China, Hefei 230026)(State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chine | 1998 | Chinese Chemical Letters1998，9，7： | 0 |
| 14 | A study of the quenching of PCl(b1∑+) by the E-V model显示文摘Using the reaction of Ar(3Po,2) + PCl3 as a source of PCl(b1 +), we have measured the quenching rate constants of PCl(b,v’=0) for more than 20 quenchers. The E-V model is used to calculate the rate constants. The comparison of the calculated values with the experimental ones shows that the quenching of PCl(b) by the reagent molecules results from the electronic to vi-brational energy near resonance transfer and has been related to the Franck-Condon factors for the PCl(b,v’=0-a,v'=m) transition and to the anharmonicities of the terminal bonds of the quenchers. In addition, the influence of the polarizability of the reagent molecule on the quenching rate constant is discussed. | LIU, Chuan-Pu ZOU, Sheng-Li GUO, Jing-Zhong GU, Yue-ShuDepartment of Chemistry, Shandong University, Jinan, Shandong 250100, ChinaCHU, Yan-Nan CAO, De-ZhaoLaser Spectroscopy Laboratory, Anhui Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Hefei, Anhui 230031, China | 1997 | Chinese Journal of Chemistry1997，15，3： | 0 |
| 15 | PREPARATION OF ULTRAFINE ALLOY POWDER BY REDUCTION OF COMPLEX OXIDE显示文摘The ultrafine alloy powders,CuRh,γ-Ni0.33Fe0.66 and α-Fe0.66Co0.33 of size less than 35 nmwere prepared by reduction of complex metallic oxides under atmosphere of 15% H2 and85%Ar. | QIAN Yitai FU Peizhen CAO Guanghan CHEN Zuyao University of Science and Technology of China,Hefei,China Associate Professor,Department of Applied Chemistry,University of Science and Technology of China,Hefei 230026,China. | 1992 | Acta Metallurgica Sinica(English Letters)1992，5，9： | 0 |
| 16 | Reflection on methodology of the correlation between electromagnetic interference and safety in high-speed railway显示文摘Purpose – In the continuous development of high-speed railways, ensuring the safety of the operation controlsystem is crucial. Electromagnetic interference (EMI) faults in signaling equipment may cause transportationinterruptions, delays and even threaten the safety of train operations. Exploring the impact of disturbances onsignaling equipment and establishing evaluation methods for the correlation between EMI and safety isurgently needed.Design/methodology/approach – This paper elaborates on the necessity and significance of studying theimpact of EMI as an unavoidable and widespread risk factor in the external environment of high-speed railwayoperations and continuous development. The current status of research methods and achievements from theperspectives of standard systems, reliability analysis and safety assessment are examined layer by layer.Additionally, it provides prospects for innovative ideas for exploring the quantitative correlation between EMIand signaling safety.Findings – Despite certain innovative achievements in both domestic and international standard systems andrelated research for ensuring and evaluating railway signaling safety, there’s a lack of quantitative and strategic research on the degradation of safety performance in signaling equipment due to EMI. A quantitativecorrelation between EMI and safety has yet to be established. On this basis, this paper proposes considerationsfor research methods pertaining to the correlation between EMI and safety.Originality/value – This paper overviews a series of methods and outcomes derived from domestic andinternational studies regarding railway signaling safety, encompassing standard systems, reliability analysisand safety assessment. Recognizing the necessity for quantitatively describing and predicting the impact ofEMI on high-speed railway signaling safety, an innovative approach using risk assessment techniques as abridge to establish the correlation between EMI and signaling safety is proposed. | Chang Liu Shiwu Yang Yixuan Yang Hefei Cao Shanghe Liu | 2024 | Railway Sciences2024，3，1： | 0 |
| 17 | Twisted Intramolecular Charge Transfer in Polydimethylsilylene Bearing Pyrenyl Groups显示文摘Polydimethylsilylenes bearing pyrenyl groups exhibit emissions fromtwisted intramolecular charge transfer state between the aromatic ring and thesilicon backbone both in polar and nonpolar solvents. | Hua Wang Zhou-Yuan Zhu University of Science and Technology of China,Hefei 230026.Bao-Wen Zhang Yi Cao Chen-Ho Tung Institute of Photographic Chemistry,Academia Sinica,Beijing 100101. | 1991 | Chinese Chemical Letters1991，2，2： | 0 |
| 18 | The dynamic properties of the two-level entangled atom in an optical field显示文摘The interaction of an optical field and one of the entangled atoms is analyzed in detail in this paper. Furthermore, the dynamic properties of the two-level entangled atom are manifested. The properties of the action are dependent on the initial state of the atom. After detecting the atom out of the field, we can obtain the state of the other atom moving in the field. It is shown that the state of the atom out of the field influences the dynamic properties of the atom in the field. | CAO Zhuo-liang, HUANG Ting,YU Ben-li (Department of Physics, Anhui University, Hefei 230039) | 2003 | 原子与分子物理学报2003，20，1： | 0 |
| 19 | Technology and test results of space adaptability of passive hydrogen maser显示文摘Based on the operating principle and the electric property design of the passive hydrogen maser, the technology and test results of its space adaptability are carried out under the special launch conditions and space environment. The various perturbations affecting the output frequency of such a standard used for the navigation satellite system are specified, such as magnetic field change, vibration, thermal vacuum and radiation. Through the adaptability technology in the aspects above, the security and reliability of the space passive hydrogen maser sufficiently fulfill the requirements of space operation. At present, the space passive hydrogen maser is working normally on board, indicating that the space adaptability satisfies the design requirement. | Hefei Zheng Lianshan Gao Keming Feng Jing Li Wenming Wang Chunyan Cao Jihong Zhang | 2017 | Journal of Systems Engineering and Electronics2017，28，2： | 0 |
| 20 | Study on transmittance spectra of ITO thin films by ellipsometric method显示文摘ITO films with thicknesses (134+8) nm, grown on glass substrates by sputtering method, were post-annealed at the temperatures of 100, 200, 300 and 400°C for 1 h, respectively. The as-deposited ITO film was amorphous, but crystallized with annealing at elevated temperatures, as demonstrated by X-ray diffraction. The transmittance spectra of all samples were obtained and subsequently simulated by means of spectroscopic ellipsometry. The optical constants n and k of the films were extracted. With the annealing temperature increasing, the optical constants n and k of the films firstly decreased then increased in the whole investigated wavelength range. The optical band gaps of all films were evaluated and they varied between 3.74 and 3.93 eV. | SUN ZhaoQi1, CAO ChunBin123, CAI Qi1 & SONG XuePing1 1 School of Physics and Material Science, Anhui University, Hefei 230039, China 2 School of Sciences, Anhui Agricultural University, Hefei 230036, China 3 Key Laboratory of Opto-electronic Information Acquisition and Manipulation, Ministry of Education, Hefei 230036, China | 2010 | Science China(Technological Sciences)2010，53，7： | 0 |
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