|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Central line-associated bloodstream infection among children with biliary atresia listed for liver transplantation显示文摘BACKGROUND Pre-transplant nutrition is a key driver of outcomes following liver transplantation in children.Patients with biliary atresia(BA) may have difficulty achieving satisfactory weight gain with enteral nutrition alone,and parenteral nutrition(PN) may be indicated.While PN has been shown to improve anthropometric parameters of children with BA listed for liver transplantation,less is known about the risks,particularly infectious,associated with this therapy among this specific group of patients.AIM To describe the incidence,microbiology,and risk factors of central line-associated bloodstream infection(CLABSI) among children with BA listed for liver transplantation.METHODS Retrospective review of children aged ≤ 2-years of age with BA who were listed for primary liver transplantation at Texas Children's Hospital from 2008 through2015(n = 96).Patients with a central line for administration of PN(n = 63) were identified and details of each CLABSI event were abstracted.We compared the group of patients who experienced CLABSI to the group who did not,to determine whether demographic,clinical,or laboratory factors correlated with development of CLABSI.RESULTS Nineteen of 63 patients(30%,95%CI:19,43) experienced 29 episodes of CLABSI during 4800 line days(6.04 CLABSI per 1000 line days).CLABSI was predominantly associated with Gram-negative organisms(14/29 episodes,48%)including Klebsiella spp.,Enterobacter spp.,and Escherichia coli.The sole polymicrobial infection grew Enterobacter cloacae and Klebsiella pneumoniae.Grampositive organisms(all Staphylococcus spp.) and fungus(all Candida spp.)comprised 9/29(31%) and 6/29(21%) episodes,respectively.No demographic,clinical,or laboratory factors were significantly associated with an increased risk for the first CLABSI event in Cox proportional hazards regression analysis CONCLUSION There is substantial risk for CLABSI among children with BA listed for liver transplantation.No clinical,demographic,or laboratory factor we tested emerged as an independent predictor of CLABSI.While our data did not show an impact of CLABSI on the short-term clinical outcome,it would seem prudent to implement CLABSI reduction strategies in this population to the extent that each CLABSI event represents potentially preventable hospitalization,unnecessary healthcare dollar expenditures,and may exact an opportunity cost,in terms of missed allograft offers. | Nicole D Triggs Stacey Beer Sonam Mokha Kat Hosek Danielle Guffey Charles G Minard Flor M Munoz Ryan W Himes | 2019 | World Journal of Hepatology2019，11，2： | 2 |
| 2 | Glycoprotein E2 of classical swine fever virus:expression in insect cells and identification as a ribonuclease显示文摘 | Hulst M M Himes G Newbigin E | 1994 | Virology1994，，200： | 1 |
| 3 | The γ-secretase inhibitor N--S-pbenylglycine t-butyl ester reduces Aβ levels in vivo in plasma and cerebrospinal fluid in young ( plaque-free ) and aged ( plaque-bearing ) Tg2576 mice 显示文摘 | LANZ T A HIMES C S PALLANTE G | 2003 | J Pharmacol Exp Ther2003，305，3： | 1 |
| 4 | Sulfate attack,' or is it显示文摘 | Hime W G Mather B | | 0，，05： | 1 |
| 5 | A relational model of mortality at older ages in low mortality countries 显示文摘 | Himes C L Preston S H Condran G A | 1994 | Population Studies1994，48，2： | 1 |
| 6 | Glycoprotein E2 of CSFV: Expression in insect cells cord identification as a ribonuclease 显示文摘 | Hulst M M Himes G Newbigin E | 1994 | Virology1994，200，： | 1 |
| 7 | Glycoprotein E2 of classical swine fever virus: expression in insect cell and identification as a ribonuclease 显示文摘 | Hulst M M Himes G Newbigin E | 1994 | Virology1994，200，2： | 1 |
| 8 | Salt hydration distress显示文摘 | W G Hime R A Martinek L A Backus | 2001 | Concr Int2001，23，10： | 1 |
| 9 | Sulfate attack or is it显示文摘 | W G Hime B Mater | 1999 | Cem Concr Res1999，29，： | 1 |
| 10 | Stereochemistry of the human macular carotenoids显示文摘 | Bone R A Landrum J T Hime G W | 1993 | Invest Ophthalmol Vis Sci1993，34，： | 1 |
| 11 | Glycoprotein E2 of classical swine fever virus:expression in insect cells and identification as a ribonuclease显示文摘 | Hulst M M Himes G Newbigin E | 1994 | Virology1994，200，2： | 1 |
| 12 | Glycoprotein E2 of classical swine virus: Expression in insect cells and identification as a ribonuclease 显示文摘 | Hulst M M Himes G Moormann R J M | 1994 | Journal of Virology1994，200，： | 1 |
| 13 | 'Sulfate attack',or is it显示文摘 | HIME W G MATI~ER B | 1999 | Cement and Con- crete Research1999，29，5： | 1 |
| 14 | Investigation of prestressed concrete railway tie distress显示文摘 | MIELENZ R C MARUSIN S L HIME W G | 1995 | Concr Int1995，17，12： | 1 |
| 15 | Glyeoprotein E2 of classical swine fever virus: expression in insect cells and identification as a ribonuclease 显示文摘 | Hulst M M Himes G Newbigin E | 1994 | Virology1994，200，2： | 1 |
| 16 | Glyco- protein E2 of classical swine fever virus : expression in in- sect cells and identification as a ribonuclease显示文摘 | HULST M M HIMES G NEWBIGIN E D | 1994 | Virolo- gy1994，200，2： | 1 |
| 17 | Glycoprotein Ew of CSFV: Expression in insect cells cord identification as a ribonuclease显示文摘 | Huslt M M Himes G Newbigin E | 1994 | Virology1994，，200： | 1 |
| 18 | Salt hydration distress observations-an unidentified or misidentified cause of concrete distress显示文摘 | G H Hime Martinek R A Backus LA | 2001 | Concrete international2001，，10： | 1 |
| 19 | Glycoprotein Erns of classical swine virus: Expression in insect ceils and identification as a ribonuclease显示文摘 | Hulst M M Himes G Moomann R J M | 1994 | Virology1994，200，： | 1 |
| 20 | Glycoprotein E2of classical swine fever virus:expression in insect cells and identification as a ribonuclease显示文摘 | Hulst MM Himes G Newbigin E | 1994 | Virology1994，200，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员