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| 1 | Effect of TGF-131 antisense oligodeoxynucleotide on renal function in chronic renal failure rats显示文摘目的:学习是调查转变生长因素( TGF )贝它 1 反的有效性的礼品的目的在改善察觉到 oligodeoxynucleotides ( ODN )在有 导致puromycin 的长期的肾衰竭( CRF )的老鼠的败坏的肾功能 .Methods :盐,嘌呤霉素,puromycin+TGF贝它 1 反感觉 ODN 或 puromycin+scrambled ODN 予被以单方地 nephrecto-mized 老鼠。肾的血液动力学、分泌的大小在经历了外科的 procedure.Results 的使麻木的老鼠被拿:在 CRF 老鼠,在肾的血流( RBF )有显著减小,这被观察, glomerular 率( GFR ),严重蛋白尿,并且几乎6褶层在控制老鼠作为与那相比增加了钠( FE Na^+)的部分排泄(所有 P < 0.05 )。在 CRF 老鼠,有 1 反察觉到的 TGF 贝它的处理,然而并非爬的 ODN,显著地稀释了 RBF, GFR,和蛋白尿的减小并且显著地阻止了 FE Na^+ 的增加,这进一步被观察(所有 P < 0.05 ) 。另外,在 CRF 的肾的肥大组织(P < 0.05 对非肾的失败控制) 是有 TGF-1 反感觉 ODN 的显著地稀释的术后疗法(P < 0.05 ) 。焦点的部分肾小球硬化症在未经治疗、爬的对待 ODN 的 CRF 组仅仅是明显的。这研究的有趣的观察在 CRF 老鼠是那,尽管有显著 attenuating 和TGF贝它的预防效果败坏的肾的功能上的 1 反感觉 ODN ,反感觉处理没在TGF贝它的肾的表示引起任何显著变化 1 在蛋白质 level.Conclusion :一起,获得的数据建议 1 反感觉 ODN 拥有的那TGF贝它在 导致puromycin 的长期的肾衰竭的有益的效果并且在形态学的恶化和处于这个病理学的状态的损害肾的功能部分地依赖于TGF贝它的行动 1 在肾以内。 | Law Chung HIONG Kiew Lik VOON Nor Azizan ABDULLAH Munavvar A SATTAR Nazarina Abdul RAHMAN Abdul Hye KHAN4, Edward James JOHNS | 2008 | Acta Pharmacologica Sinica2008,29,4: | 7 |
| 2 | Randomized Clinical Trial of Cutting Balloon Angioplasty versus High-Pressure Balloon Angioplasty in Hemodialysis Arteriovenous Fistula Stenoses Resistant to Conventional Balloon Angioplasty显示文摘 | Syed Arafat Aftab Kiang Hiong Tay Farah G. Irani Richard Hoau Gong Lo Apoorva Gogna Benjamin Haaland Seck Guan Tan Siew Png Chng Shanker Pasupathy Hui Lin Choong Bien Soo Tan | 2013 | Journal of Vascular and Interventional Radiology2013,,: | 2 |
| 3 | Glabal and local interactions in tourism 显示文摘 | Peggy Teo Lira Hiong Li | 2003 | Annals of Tourism Research2003,30,2: | 1 |
| 4 | Thyrotoxic periodic paralysis:reports of seven patients presenting with weakness in an Asian emergency department显示文摘 | S Hiong Goh | 2002 | Emerg Med J2002,19,: | 1 |
| 5 | A case of cata-strophic pulmonary vasoconstriction after protamine ad-ministration in cardiac surgery: role of intraoperativetransesophageal echocardiography 显示文摘 | Hiong YT Tang YK Chui WH | 2008 | J CardiothoracVase Anesth2008,22,5: | 1 |
| 6 | Sur la limition de T(r,f) sans intervention des poles显示文摘 | HIONG K L | 1956 | Bull Sci Math1956,80,: | 1 |
| 7 | 对于非酒精性脂肪肝病的认识——基于亚洲人群的研究显示文摘背景和目的:非酒性脂肪肝病(NAFLD)是最常见的慢性肝病,同时也是代谢综合征的一项危险因素。NAFLD在全球范围内的患病率基于地域差异在5%~30%不等。尽管流行病学资料显示代谢相关性疾病的患病率在新加坡呈快速增长,但对于该地区NAFLD的数据却十分有限。本研究旨在了解新加坡NAFLD的患病率及公众对该病的认识。方法:本研究是一项横断面观察研究,旨在评估NAFLD患者的人口统计学、人体测量学及临床资料,研究对象来自于一项胃肠公众论坛的参会者。NAFLD的诊断基于超声学标准;代谢综合征的诊断则基于国际糖尿病联盟的指南。通过自行设计的调查问卷来了解大家对NAFLD这种疾病的看法。结果:共有227名研究对象纳入研究,其中40%被诊断为NAFLD。相对于那些非NAFLD人群,NAFLD者男性居多,年龄更大,体质指数更高,腰围更宽,患代谢性综合征的比例更高(均P<0.05)。尽管有71.2%的研究对象之前听说过NAFLD,但其中仅25.4%认为自己具有NAFLD的风险。有无代谢风险因素者对NAFLD的认识差不多(P>0.05)。值得注意的是,75.6%的具有代谢危险因素者,并不认为自己存在NAFLD风险。结论:我们的研究显示NAFLD在新加坡具有较高的患病率,包括在那些非肥胖人群中。考虑到人们对NAFLD的发生风险认识不足,有必要加强公众教育,以提高人们对NAFLD的认识。 | George B.B.Goh Clarence Kwan Sze Ying Lim Nanda KK Venkatanarasimha Rafidah Abu-Bakar Thinesh L Krishnamoorthy Hang Hock Shim Kiang Hiong Tay Wan Cheng Chow | 2016 | Gastroenterology Report2016,4,2: | 1 |
| 8 | Histone deacetylase inhibitors (HDACIs): multitargeted anticancer agents显示文摘 | Paul Licciardi Karagiannis Hiong Ververis | 2013 | 2013 (defa)2013,,: | 1 |
| 9 | Conjugated polyelectrolyte as signal amplifier for fluorogenic probe based enzyme activity study显示文摘 | Zhan Ruoyu Tan Angela Jun Hiong Liu Bin | | 0,,02: | 1 |
| 10 | Rectal arterio-portal fistula: An unusual cause of persistent bleeding per rectum following a proximal spleno-renal shunt显示文摘Gastrointestinal arterio-venous malformations are a known cause of gastrointestinal bleeding. We present a rare case of persistent rectal bleeding due to a rectal arterio-portal venous fistula in the setting of portal hypertension secondary to portal vein thrombosis. The portal hypertension was initially surgically treated with splenectomy and a proximal splenorenal shunt. However, rectal bleeding persisted even after surgery, presenting us with a diagnostic dilemma. The patient was re-evaluated with a computed tomography mesenteric angiogram which revealed a rectal arterio-portal fistula. Arterio-portal fistulas are a known but rare cause of portal hypertension, and possibly the underlying cause of continued rectal bleeding in this case. This was successfully treated using angiographic localizationand super-selective embolization of the rectal arterioportal venous fistula via the right internal iliac artery. The patient subsequently went on to have a full term pregnancy. Through this case report, we hope to high-light awareness of this unusual condition, discuss the diagnostic workup and our management approach. | Hao Yun Yap Ser Yee Lee Yaw Fui Alexander Chung Kiang Hiong Tay Albert Su-Chong Low Choon Hua Thng Krishnakumar Madhavan | 2013 | World Journal of Gastroenterology2013,19,25: | 1 |
| 11 | Polyaniline doped with dimethylsuffate as a polymer electrode for all solid-state power source svstem显示文摘 | RYU K S HIONG Y S PARK Y J | 2004 | Solid State Ionics2004,175,14: | 1 |
| 12 | Sur les fonctions entieres et les fonctions meromprphes d'order infini 显示文摘 | Hiong K L | 1935 | J de Math1935,14,: | 1 |
| 13 | Sur les fonctions entieres et les fonctions meromprhes d'order infini 显示文摘 | HIONG K L | 1935 | J de Math1935,14,: | 1 |
| 14 | Global and local interactions in tourism显示文摘 | Peggy Teo Lim Hiong Li | 2003 | Annals of Turism Research2003,30,2: | 1 |
| 15 | Histone deacety-lase inhibitors (HDACIs) : multitargeted anticancer agents 显示文摘 | Ververis K Hiong A Karagiannis TC | 2013 | Biologies2013,7,2: | 1 |
| 16 | Analysis of the two-degree-of-freedom wing rock in advanced aircraft显示文摘 | Tiauw Hiong Go Rudrapatna V Ramnath | 2002 | Journal of Guidance Control and Dynamics2002,25,2: | 1 |
| 17 | Sue les functions entieres et les functions meronorphic d'ordre infini 显示文摘 | Hiong Kiong-lai | 1935 | de Math t1935,14,: | 1 |
| 18 | Sur la limitation de T(r,f) sans intervention des poles 显示文摘 | Hiong K L | 1956 | Bull Sci Math1956,80,: | 1 |
| 19 | Sur Les Fonctions Entieres et Let Fonctions Meromorphes D′ordre Infini显示文摘 | HIONG Kinlai | 1935 | J Math Pures et Appl1935,14,: | 1 |
| 20 | Sur les fonctions entieres et les fonctions meromorphes d'ordre infini 显示文摘 | Hiong K L | 1935 | J de Math1935,14,: | 1 |