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| 1 | A CIN-like TCP transcription factor(LsTCP4)having retrotransposon insertion associates with a shift from Salinas type to Empire type in crisphead lettuce(Lactuca sativa L.)显示文摘To improve several agronomic traits in crisphead lettuce(Lactuca sativa L.)under high-temperature growth conditions,we investigated the correlation among those traits in multiple cultivars and performed genetic mapping of their causal genes.In a field cultivation test of Empire type(serrated leaf)and Salinas type(wavy leaf)cultivars,Empire type cultivars showed increased tipburn susceptibility and late bolting compared with Salinas type cultivars.We attempted genetic mapping of leaf shape and bolting time by ddRAD-seq using the F2 population derived from a cross between‘VI185’(Empire type)and‘ShinanoGreen’(Salinas type).These analyses suggested that both traits are controlled by a single locus in LG5.Genotyping of 51 commercial lettuce cultivars with a tightly linked marker(LG5_v8_252.743Mbp)at this locus showed an association between its genotype and the serrated leaf phenotype.By further fine mapping and transcriptome analysis,a gene encoding putative CIN-like TCP transcription factor was determined to be a candidate gene at this locus and was designated as LsTCP4.An insertion of retrotransposable element was found in the allele of‘VI185’,and its transcript level in the leaves was lower than that in‘ShinanoGreen’.Because shapes of leaf epidermal cells in‘VI185’were similar to those in the TCP family mutant of Arabidopsis thaliana,the leaf shape phenotype was likely caused by reduced expression of LsTCP4.Furthermore,because it is known that the TCP family protein also controls flowering time via interaction with FT in A.thaliana,it was highly possible that LsTCP4 gave pleiotropic effects on both leaf shape and bolting time in lettuce. | Kousuke Seki Kenji Komatsu Keisuke Tanaka Masahiro Hiraga Hiromi Kajiya-Kanegae Hideo Matsumura Yuichi Uno | 2020 | Horticulture Research2020，7，1： | 7 |
| 2 | 二噁英引起斑马鱼下颌短小及其与Sonic hedgehog基因的关联显示文摘环境污染物二噁英中毒性最强的2,3,7,8-四氯二苯并对二噁英(2,3,7,8-tetrachlorodibenzo-p-dioxin,以下简称TCDD)经由芳烃基受体(arylhydrocarbonreceptor,Ahr)引起啮齿类口唇开裂,斑马鱼下颌短小等典型特征.本试验研究了TCDD引起的下颌短小与形态发育基因.Sonichedgehog(shh)的关系.用0—1.0μg/L的TCDD给受精后24h(24hpf)的斑马鱼胚染毒直至观察并进行形态学观察及原位杂交.结果观察到TCDD引起斑马鱼的下颌短小与其浓度相依存,同时观察到TCDD染毒群的Shh基因表达以及类似基因tiggy-winkleheagehog(twhh)的低下.观察Shh缺失的斑马鱼变异体Syu,或给正常斑马鱼染毒,添加Shh阻断药CycopamanCyclopamine,可以同样观察到斑马鱼的下颌短小.本试验表明TC-DD引起的下颌短小与shh和twhh表达是相关联的.同时也说明斑马鱼有可能作为二噁英类污染物的生物学毒性评价生物. | 董武 杨景峰 曹颖霞 王思珍 Hiroki Teraoka Takeo Hiraga | 2005 | 湖泊科学2005，17，2： | 3 |
| 3 | A Biomechanical Comparison of Repair Techniques for Anterior Cruciate Ligament Tibial Avulsion Fracture Under Cyclic Loading显示文摘 | Harehiko Tsukada Yasuyuki Ishibashi Eiichi Tsuda Yasuharu Hiraga Satoshi Toh | 2005 | Arthroscopy: The Journal of Arthroscopic and Related Surgery2005，，10： | 2 |
| 4 | Formation of 14H long period stacking ordered structure and profuse stacking faults in Mg–Zn–Gd alloys during isothermal aging at high temperature显示文摘 | Michiaki Yamasaki Minami Sasaki Masahiko Nishijima Kenji Hiraga Yoshihito Kawamura | 2007 | Acta Materialia2007，，20： | 2 |
| 5 | Transmission electron microscopy study of the evolution of precipitates in aged Al–Li–Cu alloys: the θ ′ and T 1 phases显示文摘 | Ritsuko Yoshimura Toyohiko J Konno Eiji Abe Kenji Hiraga | 2003 | Acta Materialia2003，，14： | 2 |
| 6 | An HR-induced tobacco peroxidase gene is responsive to spermine,but not to salicylate,methyl jasmonate,and ethephon显示文摘 | Hiraga S Ito H Yamakawa H | 2000 | Molecular PlanT-Microbe Interactions2000，13，2： | 1 |
| 7 | Effects of the ccd function of the F plasmid on bacterial growth显示文摘 | Jaffe A Ogura T Hiraga S | 1985 | J Bacteriol1985，163，3： | 1 |
| 8 | Multiple functions 'of ergosterol in the fission yeast Schizosaccharomyces pombe 显示文摘 | Iwaki T Lefuji I4 Hiraga Y | 2008 | Microbiology2008，154，3： | 1 |
| 9 | Involvement of cell- cell and cell-matrix interactions in bone destruction induced by metastatic MDA-MB-231 human breast cancer cells in nude mice 显示文摘 | Nakamura H Hiraga T Ninomiya T | 2008 | J Bone Miner Metab2008，26，6： | 1 |
| 10 | A New Digalactosyl Diacylglycerol from a Cultured Marine Dinoflagellate Heterocapsa circularisquama显示文摘 | Hiraga Y Kaku K Omoda D | 2002 | J Nat Prod2002，65，： | 1 |
| 11 | A large family of class III plant peroxidases 显示文摘 | Hiraga S Sasaki K ho H | 2001 | Plant Cell Physiol2001，42，5： | 1 |
| 12 | Practical evaluation of a mouse with chimeric human liver model for hepatitis C virus infection using an NS3- 4A protease inhibitor显示文摘 | Kamiya N lwao E Hiraga N Tsuge M | 2010 | J Gen Virol2010，91，7： | 1 |
| 13 | Hypertriglyceridernia, but not hypercholesterolemia, is associated with the alteration of fibrinolytic system显示文摘 | Hiraga T Shimada M Tsukada T | 2000 | Horm Metab Res2000，28，11： | 1 |
| 14 | The bisphosphonates inbandronate promotes apoptosis in MDA-MB-231 human breast cancer cells in bone metastases显示文摘 | Hiraga T Williams PJ Mundy GR | | 0，，11： | 1 |
| 15 | Involvement of cell-cell and cell-matrix interactions in bone destruction induced by metastatic MDA-MB-231 human breast can- cer cells in nude mice显示文摘 | Nakamura H Hiraga T Ninomiya T | 2008 | J Bone Miner Metab2008，2，6： | 1 |
| 16 | Identification of ThreeExercise-induced Mortality Risk Factors in Patients with COPD显示文摘 | Yoshimura K Maekura R Hiraga T | 2014 | COPD2014，11，6： | 1 |
| 17 | Atomic structures and stability of hexagonal BN, diamond and Au multiply-twinned nanoparticles with fivefold symmetry 显示文摘 | Oku T Hiraga K | 2000 | Diamond Relat Mater2000，10，： | 1 |
| 18 | Mini-F plasid genes that couple host cell division to plasmid prolifcration显示文摘 | Ogura J Hiraga S | 1998 | Proc Natl Acid Sci1998，16，3： | 1 |
| 19 | Plasma assisted molecular beam epitaxy of ZnO on c-plane sapphire-Crowth and characterization 显示文摘 | CHEN Y F BAGNALL D M KOH H J PARK K T HIRAGA K J ZHU Z Q YAO T F | 1998 | Journal of Applied Physics1998，84，： | 1 |
| 20 | Developments in Steel Cord Wire Rods 显示文摘 | Takaaki Minamida Noriaki Hiraga Takao Shibata | 2000 | Kobe Steel Engineering Reports2000，50，3： | 1 |
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