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| 1 | Upper-gastrointestinal bleeding secondary to peptic ulcer disease:Incidence and outcomes显示文摘AIM:To evaluate the incidence,surgery,mortality,and readmission of upper gastrointestinal bleeding(UGIB)secondary to peptic ulcer disease(PUD).METHODS:Administrative databases identified all hospitalizations for UGIB secondary to PUD in Alberta,Canada from 2004 to 2010(n=7079)using the International Classification of Diseases Codes(ICD-10).A subset of the data was validated using endoscopy reports.Positive predictive value and sensitivity with 95%confidence intervals(CI)were calculated.Incidence of UGIB secondary to PUD was calculated.Logistic regression was used to evaluate surgery,in-hospital mortality,and 30-d readmission to hospital with recurrent UGIB secondary to PUD.Co-variants accounted for in our logistic regression model included:age,sex,area of residence(i.e.,urban vs rural),number of Charlson comorbidities,presence of perforated PUD,undergoing upper endoscopy,year of admission,and interventional radiological attempt at controlling bleeding.A subgroup analysis(n=6356)compared outcomes of patients with gastric ulcers to those with duodenal ulcers.Adjusted estimates are presented as odds ratios(OR)with95%CI.RESULTS:The positive predictive value and sensitivity of ICD-10 coding for UGIB secondary to PUD were85.2%(95%CI:80.2%-90.2%)and 77.1%(95%CI:69.1%-85.2%),respectively.The annual incidence between 2004 and 2010 ranged from 35.4 to 41.2 per100000.Overall risk of surgery,in-hospital mortality,and 30-d readmission to hospital for UGIB secondary to PUD were 4.3%,8.5%,and 4.7%,respectively.Interventional radiology to control bleeding was performed in 0.6%of patients and 76%of these patients avoided surgical intervention.Thirty-day readmission significantly increased from 3.1%in 2004 to 5.2%in 2010(OR=1.07;95%CI:1.01-1.14).Rural residents(OR rural vs urban:2.35;95%CI:1.83-3.01)and older individuals(OR≥65 vs<65:1.57;95%CI:1.21-2.04)were at higher odds of being readmitted to hospital.Patients with duodenal ulcers had higher odds of dying(OR=1.27;95%CI:1.05-1.53),requiring surgery(OR=1.73;95%CI:1.34-2.23),and being readmitted to hospital(OR=1.54;95%CI:1.19-1.99)when compared to gastric ulcers.CONCLUSION:UGIB secondary to PUD,particularly duodenal ulcers,was associated with significant morbidity and mortality.Early readmissions increased over time and occurred more commonly in rural areas. | Samuel Quan Alexandra Frolkis Kaylee Milne Natalie Molodecky Hong Yang Elijah Dixon Chad G Ball Robert P Myers Subrata Ghosh Robert Hilsden Sander Veldhuyzen van Zanten Gilaad G Kaplan | 2014 | World Journal of Gastroenterology2014,20,46: | 21 |
| 2 | Dynamic analysis of a flexible hub-beam system with tip mass显示文摘 | Cai G P Hong J Z Yang S X | 2005 | Mechanics Research Communications2005,32,2: | 1 |
| 3 | Corrosion control methods in supercritical water oxidation and gasification processes显示文摘 | Marronea P A Hong G T | 2009 | Supercritical Fluids2009,,51: | 1 |
| 4 | Corrosion control methods in supercritical water oxidation and gasification process 显示文摘 | Marrone P A Hong G T | 2009 | The Journal of Supercritical Fluids2009,51,2: | 1 |
| 5 | A novel design of an air-core type permanent magnet linear brushless motor by space harmonics field analysis显示文摘 | KANG G H HONG J P KIM G T | 2001 | IEEE Transaetiolas on Magnetics2001,37,5: | 1 |
| 6 | The effects of high pressure and various binders on the physico-chemical properties of restructured pork meat 显示文摘 | HONG G P PARK S H KIM J Y | 2006 | Asian-Australasian Journal of Animal Sciences2006,19,10: | 1 |
| 7 | Modeling study of a flexible hub beam system with large motion and with considering the effect of shear deformation显示文摘 | You C L Hong J Z Cai G P | 2006 | Journal of Vibration and Acoustics2006,,295: | 1 |
| 8 | Overexpression of △1-pyrroline-5-carboxylate synthetase increases proline over production and confers osmo-tolerance in transgenic plants 显示文摘 | Kavi Kishor P B K Hong Z Miao G | 1995 | Plant Physiology1995,108,4: | 1 |
| 9 | Overexpression of Dlpyrroline-5-carboxylate synthetase increases proline production and confers osmotolerance in transgenic plants 显示文摘 | Kishor B P K Hong Z Miao G H | 1995 | Plant Physiology1995,108,: | 1 |
| 10 | Takot subo cardiomyopathy (left ventricular ballooning syn drome) induced during dobutamine stress echocardio graphy显示文摘 | SILBERBAUER J HONG P LLOYD G W | 2008 | Eur J Echocardiogr2008,9,: | 1 |
| 11 | Overexpression of △-Pyrroline-5-carboxylate synthetase increse proline production and confers osmotolerance in transgenic plants 显示文摘 | Hong Z Miao G H | 1987 | Plant Physiol1987,83,: | 1 |
| 12 | A Study of Adsorption Kinetics and Thermodynamics of ω-Mercaptoalkylhydroquinone Self-Assembled Monolayer on a Gold Electrode显示文摘 | Hong H G Wonchoul P | 2005 | Electrochimica Acta2005,51,4: | 1 |
| 13 | Overcxpression of pyrroline-5-carboxylase synthasc increase proline production and confers osmotolerance in transgenic plants显示文摘 | Kishor P B K Hong Z Miao G | 1995 | Plant Physiol1995,108,: | 1 |
| 14 | Over expression of △-pyrroline-5-carb oxylate synthetase increases proline production and confers osmotolerance in transgenic plants显示文摘 | Kavi Kishor P B Hong Z Miao G H Hu C A Verma D P S | 1995 | Plant Physiol1995,108,: | 1 |
| 15 | Effect of 1- phenylsulfonyl]-3-(trans-4-methyl- cyclohexyl) urea( 14 ), a new synthetic sulfonylurea compound, on glucose metabolism in vivo and in vitro 显示文摘 | Wu G Z Hong G Zhang W P | 2009 | Rzneimittelforschung2009,59,11: | 1 |
| 16 | High production of lacca- se by a new basidiomycete, Trametes sp显示文摘 | Tong P G Hong Y Z Xiao Y Z | 2007 | Biotechnol Lett2007,29,: | 1 |
| 17 | Relationship between structural properties and CO2 capture performance of CaO-based sorbents obtained from different organometallic precursors 显示文摘 | LU Hong KHAN A SMIRNIOTIS P G | 2008 | Industrial & Engineering Chemistry Research2008,47,16: | 1 |
| 18 | Multi-category micro-milling tool wear monitoring with continuous hidden Markov models 显示文摘 | Zhu K P Wong Y S Hong G S | 2009 | Mechanical Systems and Signal Processing2009,23,2: | 1 |
| 19 | The amylose content in rice endosperm is related to the post-transcriptional regulation of the waxy gene显示文摘 | Wang Z Y Zheng F Q Shen G Z Gao J P Snusted D P Li M G Zhang J L Hong M M | 1995 | The Plant Journal1995,7,4: | 1 |
| 20 | Over expression of D1-pyrroline-5-car-boxylate synthetase increases proline production and confers osmotolerance in transgenic plants显示文摘 | Kavi-Kishor P B K Hong Z Miao G H Hu C A A Verma D P S | 1995 | Plant physiol1995,108,: | 1 |