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| 1 | Protective effects of Yindanxinnaotong capsule in a rat model of myocardial ischemia/reperfusion injury显示文摘OBJECTIVE: To investigate the effects of Yindanxinnaotong capsule(YDXNTC) and main components compatibility and ratios on myocardium against ischemia/reperfusion injury and the effect's underlying mechanism.METHODS: Myocardial ischemia/reperfusion injury(MIRI) was induced by ischemia for 30 min and reperfusion for 30 min. Electrocardiogram data and coronary flow were recorded, and superoxide dismutase(SOD), malondialdehyde(MDA), lactate dehydrogenase, creatine kinase-MB, cardiac troponin T and I(cT nT, cT n I) and interleukin-1β, interleukin-8,interleukin-18(IL-1β, IL-8, IL-18) in myocardium were measured. Hypoxia/reoxygenation and hydrogen peroxide(H2O2) injury were induced by hypoxia for 3 h/reoxygenation for 2 h, and 100 μM H2O2 for 1 h, respectively, in vitro rat myocardial cells(H9c2). Cell viability, SOD, MDA, cT nT and inflamma-tory factors(IL-1β, IL-8 and IL-18) were determined,and Toll-like receptor 4(TLR-4) expression was measured by western blotting.RESULTS: In the isolated heart experiment, elevated heart function, coronary flow and SOD levels,and decreased MDA levels and inflammatory factors were noted in the YDXNTC, main components and main components compatibility groups. Ventricular tachycardia/ventricular fibrillation occurrence decreased in the ginkgo biloba extract(GBE),and GBE and salvia miltiorrhiza ethanol extract compatibility(SM-E, GSEC) groups. Lactic dehydrogenase levels decreased in the YDXNTC and aqueous extract of salvia miltiorrhiza(SM-H) groups. Creatine kinase-MB decreased with GBE, SM-E, SM-H and GSEC treatment, and cT n I and cT nT levels decreased with GSEC. In the in vitro cell study,YDXNTC and main components ratios improved cell viability and SOD levels, and suppressed MDA,cT nT and inflammatory factors. TLR-4 expression was down-regulated.CONCLUSION: YDXNTC and main components compatibility showed protective effects on MIRI in this rat model and in vitro study. Regulating the Toll-like receptor signaling pathway may affect the mechanism. | Wandan Wang Lan Wang Hongjun Yang Jianlu Wang Xiaojie Yin Haiyu Xu Long Cheng Rixin Liang | 2014 | Journal of Traditional Chinese Medicine2014，34，6： | 22 |
| 2 | Developing controllable hypermutable Clostridium cells through manipulating its methyl-directed mismatch repair system显示文摘Development of controllable hypermutable cells can greatly benefit understanding and harnessing microbial evolution.However,there have not been any similar sys-tems developed for Clostridium,an important bacterial genus.Here we report a novel two-step strategy for de-veloping controllable hypermutable cells of Clostridium acetobutylicum,an important and representative indus-trial strain.Firstly,the mutS/L operon essential for methyl-directed mismatch repair(MMR)activity was inactivated from the genome of C.acetobutylicum to generate hy-permutable cells with over 250-fold increased mutation rates.Secondly,a proofreading control system carrying an inducibly expressed mutS/L operon was constructed.The hypermutable cells and the proofreading control system were integrated to form a controllable hypermut-able system SMBMutC,of which the mutation rates can be regulated by the concentration of anhydrotetracycline(aTc).Duplication of the miniPthl-tetR module of the proof-reading control system further signifi cantly expanded the regulatory space of the mutation rates,demonstrating hypermutable Clostridium cells with controllable mutation rates are generated.The developed C.acetobutylicum strain SMBMutC2 showed higher survival capacities than the control strain facing butanol-stress,indicating greatly increased evolvability and adaptability of the controllable hypermutable cells under environmental challenges. | Guodong Luan Zhen Cai Fuyu Gong Hongjun Dong Zhao Lin Yanping Zhang Yin Li | 2013 | Protein & Cell2013，4，11： | 4 |
| 3 | 车用汽油机排气污染控制技术显示文摘本文从燃料处理、燃烧系统改进和尾气后处理等方面 ,提出了改进车用汽油机排气污染所采用的主要技术措施 。 | 李志军 饶里 黄叶舟 殷洪军 刘莹 Yin Hongjun Liu Ying | 2001 | 小型内燃机与摩托车2001，30，2： | 3 |
| 4 | Methane in soil gas and its transfer to the atmosphere in the Yakela condensed gas field in the Tarim Basin,Northwest China显示文摘In this study,by analyzing CH4 concentration and δ13CCH4 in soil-gas profiles,the potentials of CH4 gas transfer from ground to atmosphere were studied at four representative sectors in the Yakela condensed gas field in the Tarim Basin,Xinjiang,China.These are:1) the oil-gas interface sector,2) fault sector,3) oil-water interface sector,4) an external area.Variation in CH4 in soil-gas profiles showed that CH4 microseepage resulted from the migration of subsurface hydrocarbon from deep-buried reservoirs to the earth's surface.It was found that CH4 from deep-buried reservoirs could migrate upwards to the surface through faults,fissures and permeable rocks,during which some CH4 was oxidized and the unoxidized methane remained in the soil or was emitted into the atmosphere.The lowest level of CH4 at the soil-gas profile was found at the CH4 gas-phase equilibrium point at which the CH4 migration upwards from deep-buried reservoirs and the CH4 diffusion downwards from the atmosphere met.The δ13CCH4 and ethane,propane in soil gas exhibited thermogenic characteristics,suggesting the occurrence of CH4 microseepage from deep-buried reservoirs.A linear correlation analysis between CH4 concentrations in soil gas and temperature,moisture,pH,Eh,Ec and particle size of soil indicated that both soil Eh and soil temperature could affect CH4 concentration in soil gas while soil pH could indirectly influence soil methanotrophic oxidation via impacting soil Eh. | Tang Junhong Wang Guojian Yin Haoyong Li Hongjun | 2013 | Petroleum Science2013，10，2： | 2 |
| 5 | Towards low carbon development in China:a comparison of national and glohal models 显示文摘 | CHEN Wenying YIN Xiang ZHANG Hongjun | 2013 | Climatic Change2013，，10： | 1 |
| 6 | Optimiza- tion analysis of the staggered herringbone micro-mixerbased on the slip-driven method 显示文摘 | Song Hongjun Yin Xiezhen Bennett Dawn J | 2008 | Chemical Enginee- ring Research and Design2008，86，8： | 1 |
| 7 | Analysis for pressure transient of coalbed methane reservoir based on Laplace transform finite difference method显示文摘Based on fractal geometry,fractal medium of coalbed methane mathematical model is established by Langmuir isotherm adsorption formula,Fick's diffusion law,Laplace transform formula,considering the well bore storage effect and skin effect.The Laplace transform finite difference method is used to solve the mathematical model.With Stehfest numerical inversion,the distribution of dimensionless well bore flowing pressure and its derivative was obtained in real space.According to compare with the results from the analytical method,the result from Laplace transform finite difference method turns out to be accurate.The influence factors are analyzed,including fractal dimension,fractal index,skin factor,well bore storage coefficient,energy storage ratio,interporosity flow coefficient and the adsorption factor.The calculating error of Laplace transform difference method is small.Laplace transform difference method has advantages in well-test application since any moment simulation does not rely on other moment results and space grid. | Lei Wang Hongjun Yin Xiaoshuang Yang Chuncheng Yang Jing Fu | 2015 | Petroleum2015，1，3： | 1 |
| 8 | Towards low carbon development in China:A comparison of national and global models显示文摘 | CHEN Wenying YIN Xiang ZHANG Hongjun | 2013 | Climatic Change2013，，1： | 1 |
| 9 | Towards low carbon development in China:A comparison of national and global models显示文摘 | CHEN Wenying YIN Xiang ZHANG Hongjun | 2013 | Climatic Change2013，，： | 1 |
| 10 | The association between physical functioning and self-rated general health in later life: The implications of social comparison 显示文摘 | Yin Hongjun Lin SJ Kong SX | 2011 | Appl Res Qual Life2011，6，1： | 1 |
| 11 | Functional de- clines, social, support, and mental health in the elderly : Does living in a state supportive of home and community--based services make a difference? 显示文摘 | Naoko Muramatsu Hongjun Yin Donald Hedeker | 2010 | Social Science Medicine2010，，： | 1 |
| 12 | Vegetation and soil properties in restored wetlands near Lake Taihu, China显示文摘 | Jinwei Lu Hongjun Wang Weidong Wang Chengqing Yin | 2007 | Hydrobiologia2007，，1： | 1 |
| 13 | Finger vein recognition with manifold learning 显示文摘 | LIU Zhi YIN Yilong WANG Hongjun | 2010 | Journal of Network and Computer Applications2010，，33： | 1 |
| 14 | Five Large Generation Groups: Competing in Capital Operation显示文摘Since the reform of electric power industry in 2002, the newly established five large generation groups have been persisting in the development strategy of 'taking electricity as the core and extending to up-and-downstream businesses.' Stringent measures were taken in capital operation and their potential has been shown through electric power as- sets acquiring, coal and financial resources investing, capital market financing as well as power utility restructuring. The five groups are playing more and more important roles in merger and acquisition (M&A) and capital markets. | Chen Zongfa and Yin Hongjun China Huadian Corporation Zhang Sufang | 2008 | Electricity2008，19，3： | 0 |
| 15 | Research on Network Cognition Model and Mechanism of Intelligent Information Network显示文摘Intellectualization has been an inevitable trend in the information network,allowing the network to achieve the capabilities of self-learning,self-optimization,and self-evolution in the dynamic environment.Due to the strong adaptability to the environment,the cognitive theory methods from psychology gradually become an excellent approach to construct the intelligent information network(IIN),making the traditional definition of the intelligent information network no longer appropriate.Moreover,the thinking capability of existing IINs is always limited.This paper redefines the intelligent information network and illustrates the required properties of the architecture,core theory,and critical technologies by analyzing the existing intelligent information network.Besides,we innovatively propose a novel network cognition model with the network knowledge to implement the intelligent information network.The proposed model can perceive the overall environment data of the network and extract the knowledge from the data.As the model’s core,the knowledge guides the model to generate the optimal decisions adapting to the environmental changes.At last,we present the critical technologies needed to accomplish the proposed network cognition model. | Nannan Dong Hao Yin Baoquan Ren Hongjun Li Xiangwu Gong Xudong Zhong Junmei Han Jiazheng Lyu | 2023 | China Communications2023，20，2： | 0 |
| 16 | The residual oil distribution regularity of low permeability oilfield显示文摘Study on the residual oil distribution regularity is the important thing during the middle and later stage of the oilfield.With understanding and development of oilfield,the research methods of remaining oil are varied.Well block A is a low permeability oilfield and complex relationship between injection wells and production wells.The well pattern has low control of sand body.Based on the characteristics and the geological and dynamic data,technology of integrated 3-D geological modeling with reservoir numerical simulation is ensured to study the residual oil.Finally,deposition facies and flowing units are studied to analyze the residual oil distribution regularity.As a result,the types of residual oil were confirmed and the basis for the following development adjustment of the well block is provided. | Huan Zhao Hongjun Yin | 2015 | Petroleum2015，1，2： | 0 |
| 17 | Preparation and Chiral Recognition of Thermosensitive Poly(N-isopropylacrylamide) Microgels Containing Modified L-Phenylalanine Groups显示文摘 | CHEN Jiaojiao YIN Yue FU Hongjun LI Qifeng ZOU Jiwei | 2015 | Chemical Research in Chinese Universities2015，31，4： | 0 |
| 18 | A phylogenetic approach identifies patterns of beta diversity and floristic subregions of the Qinghai-Tibet Plateau显示文摘Patterns of taxonomic and phylogenetic beta diversity and their relationships with environmental correlates can help reveal the origin and evolutionary history of regional biota.The Qinghai-Tibet Plateau(QTP)harbors an exceptionally diverse flora,however,a phylogenetic perspective has rarely been used to investigate its beta diversity and floristic regions.In this study,we used a phylogenetic approach to identify patterns of beta diversity and quantitatively delimit floristic regions on the Qinghai-Tibet Plateau.We also examined the relationships between multifaceted beta diversity,geographical distance,and climatic difference,and evaluated the relative importance of various factors(i.e.,climate,topography and history)in shaping patterns of beta diversity.Sørensen dissimilarity indices indicated that patterns of species turnover among sites dominated the QTP.We also found that patterns of both taxonomic and phylogenetic beta diversity were significantly related to geographical distance and climatic difference.The environmental factors that contributed most to these patterns of beta diversity include annual precipitation,mean annual temperature,climatic gradients and climatic instability.Hierarchical dendrograms of dissimilarity and non-metric multidimensional scaling ordination based on phylogenetic beta diversity data identified ten floristic subregions in the QTP.Our results suggest that the contemporary environment and historical climate changes have filtered species composition among sites and eventually determined beta diversity patterns of plants in the QTP. | Haibin Yu Man Yang Zixin Lu Weitao Wang Fangyuan Yu Yonghua Zhang Xue Yin Hongjun Yu Junjie Hu David C.Deane | 2024 | Plant Diversity2024，46，1： | 0 |
| 19 | Discovery of a novel gene involved in autolysis of Clostridium cells显示文摘Cell a utolysis plays important physiological roles in the life cycle of clostridial cells.Unders tanding the genetic ba-sis of the autolysis phenomenon of pathogenic Clostridi-um or solvent producing Clostridium cells might provide new insights into this important species.Genes that might be involved in autolysis of Clostridium acetobutylicum,a model clostridial species,were investigated in this study.Twelve putative autolysin genes were predicted in C.ace-tobutylicum DSM 1731 genome through bioinformatics analysis.Of these 12 genes,gene SMB_G3117 was select-ed for testing the in tracellular autolysin activity,growth profi le,viable cell numbers,and cellular morphology.We found that overexpression of SMB_G3117 gene led to earlier ceased growth,signifi cantly increased number of dead cells,and clear electrolucent cavities,while disrup-tion of SMB_G3117 gene exhibited remarkably reduced intracellular autolysin activity.These results indicate that SMB_G3117 is a novel gene involved in cellular autolysis of C.acetobutylicum. | Liejian Yang Guanhui Bao Yan Zhu Hongjun Dong Yanping Zhang Yin Li | 2013 | Protein & Cell2013，4，6： | 0 |
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