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3篇 您的检索式:作者名="Hongwang He"
    题名 作者 年代 出处 被引量
1Synthesis of Monodisperse CdS Nanorods Catalyzed by Au Nanoparticles显示文摘Semiconductor nanocrystals(dots,rods,wires,etc.)exhibit a wide range of electrical and optical properties that differ from those of the corresponding bulk materials.These properties depend on both nanocrystal size and shape.Compared with nanodots,nanorods have an additional degree of freedom,the length or aspect ratio,and reduced symmetry,which leads to anisotropic properties.In this paper,we report the Au nanoparticle-catalyzed colloidal synthesis of monodisperse CdS nanorods.Based on systematic high resolution transmission electron microscopy studies,we propose a growth mechanism for these nanorods.Hongwang Zhang Savas Delikanli Yueling Qin Shuli He Mark Swihart Hao Zeng 2008Nano Research2008,1,4:2
2IFN-stimulated P2Y13 protects mice from viral infection by suppressing the cAMP/EPACl signaling pathway显示文摘Among the most important sensors of extracellular danger signals, purinergic receptors have been demonstrated to play crucial roles in host defense against infection. However, the function of P2 receptors in viral infection has been little explored. Here we demonstrated that P2Y13 and its ligand ADP play an important role in protecting hosts from viral infections. First, we demonstrate that P2Y13, as a typical interferon-stimulated gene, is induced together with extracellular ADP during viral infection. Most importantly, extracellular ADP restricts the replication of different kinds of viruses, including vesicular stomatitis virus, Newcastle disease virus, herpes simplex virus 1, and murine leukemia virus. This kind of protection is dependent on P2Y13 but not P2Y1 or P2Y12, which are also considered as receptors for ADP. Furthermore, cyclic adenosine monophosphate and EPAC1 are downregu-lated by extracellular ADP through the P2Y13-coupled Gi alpha subunit. Accordingly, inhibition or deletion of EPAC1 significantly eliminates ADP/P2Y13-mediated antiviral activities. Taken together, our results show that P2Y13 and ADP play pivotal roles in the clearance of invaded virus and have the potential as antiviral targets.Chengfei Zhang Yan Yan Hongwang He Li Wang Na Zhang Jie Zhang Hongjun Huang Nannan Wu Hua Ren Min Qian Mingyao Liu Bing Du 2019Journal of Molecular Cell Biology2019,11,5:1
3An efficient preparation of porous polymeric microspheres by solvent evaporation in foam phase显示文摘This paper reports an efficient method of preparing porous polymeric microspheres by solvent evaporation in foam phase,in which phase separation between polymer and porogen occurs in foam phase instead of that in water phase by using the traditional solvent eva poration method.The method provides outstanding features,including being time-saving,of high-yield and able for continuous production,in which formation of porous polymeric microspheres finished within 3 min with a high production yield up to approximate 95 wt% and the process was able to be developed into a continuous process for production of porous polymeric microspheres.It was also universal to non-crosslinked polymers since the method is a development on the traditional emulsion solvent evaporation method.The new method is efficient and can be used potentially on the industrial scale for continuous production of porous polymeric microsphere s.Yang Yu Guiying Li Wanqing Han Linhua Zhu Tian Si HongWang Yanlin Sun Yanping He 2021Chinese Journal of Chemical Engineering2021,34,1:1
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