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1篇 您的检索式:作者名="Huang M.Guyang"
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1Bioinformatic analysis of human nuclear receptor nr5a2(hb1f) genomic sequence显示文摘We have cloned the cDNA of human nuclear receptor nr5a2(hb1f) gene and obtained its whole genomic sequence previously. In this work we carried out in-depth bioinformatic analysis on the genomic sequence of nr5a2(hb1f) gene. Sequence comparison and prediction algorithms implicated that there might be additional coding regions in the 210 kb genomic sequence besides known exons, especially in the two largest introns. Comparison of the structures of nr5a loci in different species revealed distinguishable conservation and apparent gene duplication during evolution. The remarkable conservation among promoters of zebrafish, mouse and human nr5a2 genes suggested that they would be regulated by the same transcription factors.Zhang Chengkang Lin Wei Cai Yanning Dong Hui Li Mei Fu Gang Xie Youhua Huang M.Guyang Wang Yuan 2002Chinese Science Bulletin2002,47,7:0
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