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6篇 您的检索式:作者名="Hubert Fischer"
    题名 作者 年代 出处 被引量
1Hepatitis C virus infection and apoptosis显示文摘Apoptosis is central for the control and elimination of viral infections. In chronic hepatitis C virus (HCV) infection, enhanced hepatocyte apoptosis and upregulation of the death inducing ligands CD95/Fas, TRAIL and TNFα occur. Nevertheless, HCV infection persists in the majority of patients. The impact of apoptosis in chronic HCV infection is not well understood. It may be harmful by triggering liver fibrosis, or essential in interferon (IFN) induced HCV elimination. For virtually all HCV proteins, pro- and anti-apoptotic effects have been described, especially for the core and NS5A protein. To date, it is not known which HCV protein affects apoptosis in vivo and whether the infectious virions act pro- or anti- apoptotic. With the availability of an infectious tissue culture system, we now can address pathophysiologically relevant issues. This review focuses on the effect of HCV infection and different HCV proteins on apoptosis and of the corresponding signaling cascades.Richard Fischer Thomas Baumert Hubert E Blum 2007World Journal of Gastroenterology2007,13,36:10
2CT of the head by use of reduced current and kilovoltage: relationship between image quality and dose reduction显示文摘Mathias Cohnen Hubert Fischer Jurgen Hamacher 2000AJNR2000,21,10:1
3The rubrerythrin-like protein Hsp21 of Clostridium acetobutylicum is a general stress protein显示文摘Falk Hillmann Ralf-J?rg Fischer Hubert Bahl 2006Archives of Microbiology2006,,4:1
4CT of the head by use of reduced current and kilovoltage:relationship between image quality and dose reduction显示文摘Mathlias Cohnen Hubert Fischer JUrgen Hamacher 2000AJNR2000,21,10:1
5Food stress sensitivity and flight performance across phosphoglucose isomerase enzyme genotypes in the sooty copper butterfly显示文摘Isabell Karl Klaus Hubert Hoffmann Klaus Fischer 2010Population Ecology2010,,2:1
6Bacterial?burden in the?operating room: Impact of airflow systems 显示文摘Tobias Hirsch Helmine Hubert Sebastian Fischer 2012American Journal of Infection Control2012,40,7:1
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