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| 1 | Expert Consensus on Clinical Diagnostic Criteria for Fatal Familial Insomnia显示文摘 | Li-Yong Wu Shu-Qin Zhan Zhao-Yang Huang Bin Zhang Tao Wang Chun-Feng Liu Hui Lu Xiao-Ping Dong Zhi-Ying Wu Jie-Wen Zhang Ji-Hui Zhang Zhong-Xin Zhao Fang Han Yah Huang Jun Lu Serge Gauthier Jian-Ping Jia Yu-Ping Wang | 2018 | Chinese Medical Journal2018，，13： | 10 |
| 2 | FBW7 regulates endothelial functions by targeting KLF2 for ubiquitination and degradation显示文摘F 盒子和 WD 重复包含域 7 (FBW7 ) , E3 ubiquitin ligase SCF FBW7 (SKP1, cullin-1 和 FBW7 的建筑群) ,在各种各样的生理、病理学的过程起重要作用。尽管 FBW7 为脉管的开发被要求,它在内皮细胞层的函数尚待被调查。在这研究,我们证明 FBW7 是 endothelial 功能的一个重要管理者,包括 angiogenesis,白血球粘附和 endothelial 障碍正直。用 RNA 干扰,我们发现 FBW7 的弄空显著地在 vitro 并且在 vivo 损害 angiogenesis。我们识别了锌手指抄写因素 Krü象 ppel 一样因素 2 (KLF2 ) 作为在 endothelial 房间的 FBW7 的一个生理的目标。FBW7 击倒表示在 endothelial 房间导致了内长的 KLF2 蛋白质的累积。调停 FBW7 的 KLF2 破坏被显示在二保存 phosphodegrons 经由肝糖 synthase kinase-3 (GSK3 ) 取决于 KLF2 的 phosphorylation。变异这些 phosphodegron 主题废除了 KLF2 的调停 FBW7 的降级和 ubiquitination。调停 siRNA 显示出的 FBW7 击倒 KLF2 是在 endothelial 的规定的 FBW7 的一个必要目标,这工作。而且,调停 FBW7 的 KLF2 降级被显示为在 teratomas 并且在 zebrafish 开发的 angiogenesis 批评。一起拿,我们的学习在 endothelial 房间移植, angiogenesis,发炎和障碍完整的进程为 FBW7 建议一个角色,并且在 vivo 提供新奇卓见进 KLF2 稳定性的规定。 | Rui Wang Yah Wang Ning Liu Chunguang Ren Cong Jiang Kai Zhang Su Yu Yunfei Chen Hui Tang Qi Deng Cong Fu Yingcong Wang Rong Li Mingyao Liu Weijun Pan Ping Wang | 2013 | Cell Research2013，23，6： | 7 |
| 3 | Late Neolithic expansion of ancient Chinese revealed by Y chromosome haplogroup O3alc-002611显示文摘 | Chuan-Chao WANG Shi YAN Zhen-Dong QIN Yah LU Qi-Liang DING Lan-Hai WEI Shi-Lin LI Ya-Jun YANG Li JIN Hui LI Genographic Consortium | 2013 | Journal of Systematics and Evolution2013，51，3： | 6 |
| 4 | Interaction of Chelerythrine Choloride in Acid Buffer with Calf-thymus DNA显示文摘The binding of chelerythrine (CHE) iminium to calf-thymus (CT) DNA is characterized by hypochromism and bathochromism in the absorption band, enhancement of fluorescence intensity, increase in fluorescence polarization, and the perturbation of the CD spectra of DNA. These changes are characteristic of intercalation. Scatchard plots constructed from fluorescence titration data gave a binding constant of 5.77×105 and a binding site size of 3,4 base pairs at 25℃. The intercalative interaction is exothermic with a Van’t Hoff enthalpy of -33.7 kJ/mol. In addition, *G =-32.9 kJ/mol, and *S =-2.9 J/mol/K. The intercalation of CHE into the DNA helix is enthalpy-driven. | Yah Jing SU Xiong Hui WEI | 2006 | Chinese Chemical Letters2006，17，5： | 5 |
| 5 | Properties of the quaternary ammonium walts with novel counterions 显示文摘 | Yah Hui cheng Li Qiu xiao Geng Tao | 2012 | J Surfactants Deterg2012，15，： | 1 |
| 6 | Geometric nonlinear analysis of transmission tower with continous legs 显示文摘 | Yah Hui Liu Yanjun Zhao Diansheng | 1996 | Advances in Steel Structure Pergamon1996，1，5： | 1 |
| 7 | Minimal uterine serous carcinoma with extrauterine tumor of identical morphology: an immunohistochemical study of 13 cases显示文摘 | Yah Z Hui P | 2010 | Immunohistochem Mol Morphol2010，18，1： | 1 |
| 8 | 查看详情显示文摘 | Wang Q. F Hui L Hou H Chen.J Yah C.G | | 0，，： | 1 |
| 9 | Trichosanthin suppresses Hela cell proliferation through inhibition of the PKC/MAPK signaling pathway显示文摘 | Ping Wang Li - Li Chen Hui Yah | 2008 | Cell Biol Toxicol2008，28，： | 1 |
| 10 | Effects of sesquiterpenes isolated from largehead atractylodes rhizome on growth, migra- tion, and differentiation of B16 melanoma ceils 显示文摘 | Yah Ye Chou GX Hui Wang | 2011 | Integr Cancer Ther2011，10，1： | 1 |
| 11 | Strength and drift capacity of squat recycled shear walls under cyclic loading 显示文摘 | PENG Youkai WU Hui ZHUGE Yah | 2015 | Engineer- ing structures2015，100，： | 1 |
| 12 | Liquefaction of rice straw in sub-and supercritical 1,4-dioxane-water mixture 显示文摘 | LI Hui YUAN Xin-zhong ZENG Guang-ming TONG Jing-yi YAN Yah CAO Hong-tao CHEN Ming-yang ZHANG Jia-chao YANG Dan | 2009 | Fuel Processing Technology2009，90，5： | 1 |
| 13 | Electrocatalyric oxidation of hydroquinone at poly (crystal-violet)film-modified electrode and its selective determination in the presence of O-hydroquinone and m-hydroquinone显示文摘 | ZHANG Yah ZHUANG Hui-sheng LU Hui | | 0，，02： | 1 |
| 14 | 显示文摘 | Cai Hui Yah Fengyuan Xue Qunji | 2004 | Mater Sci and Eng2004，364，： | 1 |
| 15 | Functional analysis of propeptide as an intramolecular chaperone for in vivo folding of subtilisin nattokinase 显示文摘 | JIA Yah LIU Hui BAO Wei | 2010 | FEBS Letters2010，584，23： | 1 |
| 16 | Development of an enzyme-linked immunosorbent assay using specific monoclonal antibodies against theacrine and its application显示文摘Theacrine(1,3,7,9-tetramethyluric acid),a purine alkaloid similar to caffeine in its chemical structure,is isolated from edible Camellia assamica var.kucha and has various pharmacological activities including hypnotic effects,anti-depressant effects,anti-inflammatory and analgesic effects,and a protective effect against stress-provoked liver damage.A rapid and simple assay is required to quantify theacrine in biological samples for pharmacokinetic studies in small animals.This study aimed to establish an enzyme-linked immunosorbent assay(ELISA) for theacrine quantification in blood.Herein,we successfully obtained monoclonal antibodies(MAbs) against theacrine,MAbs C11B5,and developed an ELISA method for the fast determination of theacrine in mouse blood.The range for calibration of theacrine by ELISA was 0.156-100 μg mL^1.The half maximum inhibitory concentration(IC_(50)) value was1.55 μg mL^1.The ELISA method lays a good foundation for the further research. | Zhuang Li Jun He Yue Zhang Qing-Guo Wang Yah Zhao Hui-Hua Qu Xue-Qian Wang Hui Kong Wei-Ku Zhang Jie-Kun Xu | 2016 | Chinese Chemical Letters2016，27，12： | 1 |
| 17 | Transcutaneous electricalstimulation on acupuncture points improves musclefunction in subjects after acute stroke: a randomizedcontrolled trial显示文摘 | Yah T Hui Chan C W | 2009 | Rehabil Med2009，41，5： | 1 |
| 18 | Initial adjoint variable guess technique and its application in optimal orbital transfer显示文摘 | Yah Hui Wu Hongxin | 1999 | Journal of Guidance Control and Dynamics 22(3)1999，1999，： | 1 |
| 19 | Component analysis of volaile oil from Illicium verum Hook f显示文摘 | Yah jian hui xiao Xusian Huang Kelong | 2002 | J CENT SOUTH UNIV TECHNOL2002，9，3： | 1 |
| 20 | Oridonin induces G2-M cell cycle arrest and apoptosis through MAPK and p53 signaling pathways in human hepatoma cells 显示文摘 | WANG Hui YE Yah CHU Jian-hong | 2010 | Oncology Reports2010，24，3： | 1 |
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