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| 1 | The effect of preemptive use of minimal dose fentanyl on fentanyl induced coughing 显示文摘 | Hung KC Chen CW Lin VC | 2010 | Anaesthesia2010，65，1： | 1 |
| 2 | Epidemiologic trends in nos- ocomial bacteremia in a neonatal intensive care unit 显示文摘 | Wei SH Chiu HH Hung KC | 2005 | J /Vti- crobiol Immunol Infect2005，38，4： | 1 |
| 3 | Pluronic L-81 ameliorates diabetic symptoms in db/db mice through transcriptional regulation of microsomal triglyceride transfer protein显示文摘AIM: To test whether oral L-81 treatment could im-prove the condition of mice with diabetes and to investigate how L-81 regulates microsomal triglyceride transfer protein (MTP) activity in the liver. METHODS: Genetically diabetic (db/db) mice were fed on chow supplemented with or without L-81 for 4 wk. The body weight, plasma glucose level, plasma lipid profile, and adipocyte volume of the db/db mice were assessed after treatment. Toxicity of L-81 was also evaluated. To understand the molecular mecha-nism, HepG2 cells were treated with L-81 and the effects on apolipoprotein B (apoB) secretion and mRNA level of the MTP gene were assessed.RESULTS: Treatment of db/db mice with L-81 sig-nificantly reduced and nearly normalized their body weight, hyperphagia and polydipsia. L-81 also markedly decreased the fasting plasma glucose level, improved glucose tolerance, and attenuated the elevated levels of plasma cholesterol and triglyceride. At the effective dosage, little toxicity was observed. Treatment of HepG2 cells with L-81 not only inhibited apoB secretion, but also signif icantly decreased the mRNA level of the MTP gene. Similar to the action of insulin, L-81 exerted its effect on the MTP promoter. CONCLUSION: L-81 represents a promising candidate in the development of a selective insulin-mimetic mol-ecule and an anti-diabetic agent. | Wo-Shing Au Li-Wei Lu Sidney Tam Otis King Hung Ko Billy KC Chow Ming-Liang He Samuel S Ng Chung-Man Yeung Ching-Chiu Liu Hsiang-Fu Kung Marie C Lin | 2009 | World Journal of Gastroenterology2009，15，24： | 1 |
| 4 | Advanced left ventricular dias- tolic dysfunction in uremic patients with type 2 diabetes on maintenance hemodialysis 显示文摘 | Hung KC Lee CH Chen CC | 2011 | Circulation Journal: Official Journal of the Japa- nese Circulation Society2011，76，0： | 1 |
| 5 | Parallel screeningof wild-type and drug-resistant targets for anti-resistanceneuraminidase inhibitors 显示文摘 | Hsu KC Hung HC Horng JT | 2013 | PLoS ONE2013，8，56： | 1 |
| 6 | Reversible left ventricular diastolic dysfunction on doppler tissue imaging predicts a more favorable prognosis in chronic heart failure 显示文摘 | Lee CH Hung KC Chang SH | 2012 | Circulation Journal2012，76，5： | 1 |
| 7 | The effect of pre-emptive use of minimal dose fentanyl on fentanyl-induced coughing显示文摘 | Hung KC Chen CW Lin VC | 2010 | Anaesthesia2010，65，1： | 1 |
| 8 | Epidemiologic trends in nosoeo- mial bacteremia in a neonatal intensive care unit显示文摘 | Wei SH Chiu HH Hung KC | 2005 | Microbiol Immu- nol Infect2005，38，4： | 1 |
| 9 | Incidence of fentanyl-induced cough and injection speed显示文摘 | Hung KC | | 0，，： | 1 |
| 10 | The pre-emptive analgesic effect of a cyclooxygenase-2 inhibitor in a rat model of acute postoperative pain显示文摘 | Chen JJ Hung KC Lu K | 2012 | Anaesthesia2012，67，11： | 1 |
| 11 | A novel modified method of using Trachway in- tubating stylet for awake tracheal intubation in patients with anticipated difficult airway 显示文摘 | Hung KC | 2013 | Acta Anaesthesiol Taiwan2013，51，2： | 1 |
| 12 | The possible mechanism of elonidine to suppress fen- tanybindueed coughing 显示文摘 | Hung KC | 2009 | Aeta Anaesthesiol Seand2009，53，9： | 1 |
| 13 | The effect of pre-emptive minimal dose fentanyl and coughing显示文摘 | Hung KC Chen CW Lin VCH | | 0，，： | 1 |
| 14 | Intxavitreal bevacizum-ab(Avastin)and panretinal photocoagulation in the treatment of high-risk proliferative diabetic retinopathy显示文摘 | Yang CS Hung KC Huang YM Hsu WM | 2013 | J Ocul Pharmacol TTier2013，29，6： | 1 |
| 15 | Epidemiologic trends in nosocomial bacteremia in a neonatal intensive care unit显示文摘 | Wei SH Chiu HH Hung KC | 2005 | J Micmbiol Immunol Infect2005，38，4： | 1 |
| 16 | Monotherapy with meropenem versus combination therapy with eeflazidime plus amikacin as empirical therapy for neutropenic fever in children with malignancy显示文摘 | Hung KC Chiu HH Tseng YC | 2003 | J Microbiol Immunol In- feet2003，36，4： | 1 |
| 17 | The pre-emptive analgesic effect ofa cyclooxygenase-2 inhibitor in a rat model of acute postoperative pain显示文摘 | ChenJJ Hung KC Lu K | 2012 | Anaesthesia2012，67，11： | 1 |
| 18 | Serum IL-6,albu- rain and co-morbidities are closely correlated with symptoms of depression in patients on maintenance haemodialysis显示文摘 | Hung KC Wu CC Chen HS | 2011 | Nephrol Dial Transplant2011，26，2： | 1 |
| 19 | Septic arthritis in patients with systemic lupus erythematosus: salmonella and nonsalmonella infections compared 显示文摘 | Huang JL Hung J J Wu KC | 2006 | Semin Arthritis Rheum2006，36，1： | 1 |
| 20 | The pre-emptive analgesic effect ofa cyclooxygenase-2 inhibitor in a rat model of acute postoperative pain显示文摘 | ChenJJ Hung KC Lu K | 2012 | Anaesthesia2012，67，11： | 1 |
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