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| 1 | Predicting functional outcome of ischemic stroke patients in Romania based on plasma CRP, sTNFR-1, D-Dimers, NGAL and NSE measured using a biochip array显示文摘在服的局部缺血,涉及各种各样的病理学的小径的多重 biomarkers 的评估是在甚至从疾病的早阶段估计病人的结果的一个有用工具。在这研究,我们在局部缺血的尖锐阶段调查了煽动性的地位, neuronal 破坏和第二等的纤维蛋白溶解作用的 5 外部 biomarkers 的一块面板的用途,并且在 ischemic 击以后在功能的结果上评估了这些 biomarkers 的影响。5 biomarkers (血浆 CRP, D-Dimers, sTNFR-1, NGAL 和 NSE ) 用一种生物晶片数组技术被测量。在罗马尼亚的八十九个病人用在 ischemic 击以后在 3 个月评估的修改 Rankin 规模被划分成 2 亚群;相反的功能的结果上的分析 biomarkers 的可能的影响被二项式的逻辑回归测试。有相反的结果的亚群有 CRP, NGAL, sTNFR-1 和 D-dimers 的更高的集中,但是 CRP 和 NGAL 价值不在二亚群之间是统计上不同的。univariate 血浆 biomarkers 的逻辑回归分析揭示了那 CRP, D-Dimers, NGAL, sTNFR-1 是相反的临床的结果的重要预言者。在 D-Dimers 和 sTNFR-1 的情况中,我们注意了一个增加的辨别能力(对基线临床的模型) 向统计含义与一个趋势分类差的功能的结果。在 ischemic 击的尖锐阶段期间, CRP, D-Dimers 和 sTNFR-1 的血浆集中在相反的结果病人被提高。D-Dimers 和 sTNFR-1 是在在 ischemic 击以后的 3 个月的差的结果的独立预言者。生物晶片数组技术提供可能性同时测量涉及多重 pathophysiological 小径的几个参数,在小样品卷。 | Adina HUTANU Mihaela IANCU Rodica BALASA Smaranda MAIER Minodora DOBREANU | 2018 | Acta Pharmacologica Sinica2018，39，7： | 25 |
| 2 | Helicobacter pylori and cytokine gene variants as predictors of premalignant gastric lesions显示文摘Gastric cancer remains the third leading cause of mortality from cancer worldwide and carries a poor prognosis,due largely to late diagnosis.The importance of the interaction between Helicobacter pylori(H.pylori)infection,the main risk factor,and host-related genetic factors has been studied intensively in recent years.The genetic predisposition for non-hereditary gastric cancer is difficult to assess,as neither the real prevalence of premalignant gastric lesions in various populations nor the environmental risk factors for cancer progression are clearly defined.For non-cardiac intestinal-type cancer,identifying the factors that modulate the progression from inflammation toward cancer is crucial in order to develop preventive strategies.The role of cytokines and their gene variants has been questioned in regard to non-self-limiting H.pylori gastritis and its evolution to gastric atrophy and intestinal metaplasia;the literature now includes various and non-conclusive results on this topic.The influence of the majority of cytokine single nucleotide polymorphisms has been investigated for gastric cancer but not for preneoplastic gastric lesions.Among the investigated gene variants onlyIL10T-819C,IL-8-251,IL-18RAP917997,IL-22 rs1179251,IL1-B-511,IL1-B-3954,IL4R-398 and IL1RN were identified as predictors for premalignant gastric lesions risk.One of the most important limiting factors is the inhomogeneity of the studies(e.g.,the lack of data on concomitant H.pylori infection,methods used to assess preneoplastic lesions,and source population).Testing the modifying effect of H.pylori infection upon the relationship between cytokine gene variants and premalignant gastric lesions,or even testing the interaction between H.pylori and cytokine gene variants in multivariable models adjusted for potential covariates,could increase generalizability of results. | Anca Negovan Mihaela Iancu Emoke Fulop Claudia Banescu | 2019 | World Journal of Gastroenterology2019，25，30： | 9 |
| 3 | Hepatotoxicity of anti-inflammatory and analgesic drugs:ultrastructural aspects显示文摘与导致药的肝疾病的增加的发生,正在被尝试更好在这些经常危及生活的反应后面理解机制。止痛剂和反煽动性的药是展出 hepatotoxicity 的一个主要的组。我们考察关于这些反应的研究,集中于极端结构的调查结果,它可以贡献理解和导致药的肝疾病的可能的回避。我们也在与抗氧化剂 N-acetylcysteine 或 P-glycoprotein 禁止者 verapamil 独自或在联合暴露于 acetaminophen 的临床的材料和有教养的房间上介绍一些原来的观察。 | Irena MANOV Helen MOTANIS Idan FRUMIN Theodore C IANCU | 2006 | Acta Pharmacologica Sinica2006，27，3： | 2 |
| 4 | The Color Glass Condensate显示文摘 | Francois Gelis Edmond Iancu Jamal Jalilian-Marian Raju Venugopalan | 2010 | Annual Review of Nuclear and Particle Science2010，，1： | 2 |
| 5 | 10 PW peak power femtosecond laser pulses at ELI-NP显示文摘We report on the generation and delivery of 10.2 PW peak power laser pulses,using the High Power Laser System at the Extreme Laser Infrastructure–Nuclear Physics facility.In this work we demonstrate for the first time,to the best of our knowledge,the compression and propagation of full energy,full aperture,laser pulses that reach a power level of more than 10 PW. | Christophe Radier Olivier Chalus Mathilde Charbonneau Shanjuhan Thambirajah Guillaume Deschamps Stephane David Julien Barbe Eric Etter Guillaume Matras Sandrine Ricaud Vincent Leroux Caroline Richard François Lureau Andrei Baleanu Romeo Banici Andrei Gradinariu Constantin Caldararu Cristian Capiteanu Andrei Naziru Bogdan Diaconescu Vicentiu Iancu Razvan Dabu Daniel Ursescu Ioan Dancus Calin Alexandru Ur Kazuo ATanaka Nicolae Victor Zamfir | 2022 | High Power Laser Science and Engineering2022，10，3： | 2 |
| 6 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 7 | Intuitionistic fuzzy similarity measures based on Frank t-norms family显示文摘 | Iancu I | 2014 | Pattern Recog- nition Letters2014，42，1： | 1 |
| 8 | Reconstruction of Patterns from Noisy In- puts Using Morphological Associative Memories 显示文摘 | Ritter G X Urcid G Iancu L | 2003 | Journal of Mathe- matical Imaging and Vision2003，9，： | 1 |
| 9 | Effects of statbmin inhibition on the mitotic spindle显示文摘 | Iancu C Mistry SJ Arkin S | 2001 | J Cell Sci2001，114，5： | 1 |
| 10 | Matrix metal oproteinases in cancer:comparison of known and novel aspects of their inhibition as a therapeutic approach显示文摘 | Bachmeier BE Iancu CM Jochum M | | 0，，： | 1 |
| 11 | Effects of stathmin inhibition on the mitotic spindle显示文摘 | Iancu C Mistry SJ Arkin S | 2001 | J Cell Sci2001，，： | 1 |
| 12 | Staging laparoscopy in gastric cancer, accuracy and impact on therapy显示文摘 | Muntean V Mihailov A Iancu C | 2009 | J Gastrointestin Liver Dis2009，18，2： | 1 |
| 13 | Optimization of triplex real time PCR for detecting Staphylococcus aureus mecA, pvl and nuc genes 显示文摘 | Vremer? T Iancu LS Logigan C et ol | 2011 | Roum Arch Microbiol Immunol2011，70，2： | 1 |
| 14 | Taxol and anti - stathmin thera-py :A synergistic combination that targets the mitotic spindle显示文摘 | Iancu C Mistry SJ Arkin S | 2000 | Cancer Res2000，60，13： | 1 |
| 15 | The Color Glass Condensate Condensate 显示文摘 | Francgois G Iancu E Jalilian-Marian J | 2010 | Ann Rev Nucl Part Sci2010，60，： | 1 |
| 16 | Ender nailing versus external fixation in the stabilization of type Ⅲ open tibial shaft fractures 显示文摘 | Cozma T Alexa O Iancu C | 2000 | Rev Med Chir Soc Med Nat Iasi2000，3，： | 1 |
| 17 | A software-defined commu- nication baseband design显示文摘 | GLOSSNER J IANCU D LU J | 2003 | IEEE Commun Magazine2003，，41： | 1 |
| 18 | The Colour Glass Condensate显示文摘 | Iancu E | 2003 | Nucl Phys A2003，715，： | 1 |
| 19 | Behavioral characteriza- tion of a unilateral 6-OHDA-lesion model of Parkinson's disease in mice 显示文摘 | Iancu R Mohapel P Brundin P | 2005 | Behav Brain Res2005，162，1： | 1 |
| 20 | Band gap narrowing of titanium oxide semiconductors by non- compensated anion-cation co-doping for enhanced visi- ble-light photo activity显示文摘 | ZHU W G QIU X F IANCU V | 2009 | Physical Review Letters2009，103，22： | 1 |
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