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| 1 | Relation of the IGF/IGF1R system to autophagy in colitis and colorectal cancer显示文摘Metabolic syndrome(Met S), as a chronic inflammatory disorder has a potential role in the development of inflammatory and cancerous complications of the colonic tissue. The interaction of DNA damage and inflammation is affected by the insulin-like growth factor 1 receptor(IGF1 R) signaling pathway. The IGF1 R pathway has been reported to regulate autophagy, as well, but sometimes through a bidirectional context. Targeting the IGF1 R-autophagy crosstalk could represent a promising strategy for the development of new antiinflammatory and anticancer therapies, and may help for subjects suffering from Met S who are at increased risk of colorectal cancer. However, therapeutic responses to targeted therapies are often shortlived, since a signaling crosstalk of IGF1 R with other receptor tyrosine kinases or autophagy exists, leading to acquired cellular resistance to therapy. From a pharmacological point of view, it is attractive to speculate that synergistic benefits could be achieved by inhibition of one of the key effectors of the IGF1 R pathway, in parallel with the pharmacological stimulation of the autophagy machinery, but cautiousness is also required, because pharmacologic IGF1 R modulation can initiate additional, sometimes unfavorable biologic effects. | Ferenc Sipos Hajnal Székely Imre Dániel Kis Zsolt Tulassay Gyorgyi Muzes | 2017 | World Journal of Gastroenterology2017，23，46： | 9 |
| 2 | Ozone production rate and hydroearhon reactivity in 5 urban areas: a cause of high ozone concentration in Houston 显示文摘 | Kleinman L I Daum P H Imre D | 2002 | Geophysieal Researeh Letters2002，29，10： | 1 |
| 3 | Structure, properties and interfacial interactions in poly (lactic acid )/polyurethane blends prepared by reactive processing 显示文摘 | Imre B Bed D Domj6n A | 2013 | European Polymer Journal2013，49，： | 1 |
| 4 | Single particle laser ablation time-of-flight mass spectrometer:An introduction to SPLAT显示文摘 | ZELENYUK A IMRE D | 2005 | Aerosol Science and Technology2005，39，6： | 1 |
| 5 | Determination of lorutu- dine and its active metabolite in human plasma by high-perform- ance liquid chromatography with mass spectrometry detection 显示文摘 | VLASE L IMRE S MUNTEAN D | 2007 | J Pharm Biomed Anal2007，44，3： | 1 |
| 6 | Synthesis and intercalation of silver nanoparticles in kaolinite/DMSO complexes显示文摘 | Rita Patakfalvi Imre Dékány | 2003 | Applied Clay Science2003，，3： | 1 |
| 7 | Building Sister Chromatid Cohesion: Smc3 Acetylation Counteracts an Antiestablishment Activity显示文摘 | Benjamin D. Rowland Maurici B. Roig Tatsuya Nishino Alexander Kurze Pelin Uluocak Ajay Mishra Frédéric Beckou?t Philippa Underwood Jean Metson Richard Imre Karl Mechtler Vittorio L. Katis Kim Nasmyth | 2009 | Molecular Cell2009，，6： | 1 |
| 8 | Preparation of nanosize FeS particles on SiO2 and clay mineral supports: SAXS and mssbauer spectroscopic measurements 显示文摘 | László T Zoltán H | 1996 | Colloids and Surface A:Physicochemical and Engineering Aspect1996，119，： | 1 |
| 9 | Simultaneous measurements of individual ambient particle sizea composition, effective density, and hygroscopicity 显示文摘 | Zelenyuk A Imre D Hart J H | 2008 | Analytical Chemistry2008，80，5： | 1 |
| 10 | Characterization of the Nashville urban plume on July 3 and July 18, 1995 显示文摘 | Nunnermacker L J Imre D Daum P H | 1998 | J Geophys Res1998，103，28： | 1 |
| 11 | Phenotypic Plasticity in Brook charr: Changes in Caudal Fin Induced by Water Flow 显示文摘 | IMRE I MCLAUGHLIN R L NOAKES D L G | 2002 | Journal of Fish Biology2002，61，5： | 1 |
| 12 | A high resolution study of the effect of morphology on the mass spectra of single PSL particles with Na-contalning layers and nodules 显示文摘 | Cal Y Zelenyuk A Imre D | 2006 | Aerosol Science and Technology2006，40，12： | 1 |
| 13 | Evaporation of water from particles in the aerodynamic lens inlet: An experimental study 显示文摘 | Zelenyuk A Imre D Cuadra-Rodriguez L A | 2006 | Analytical Chemistry2006，78，19： | 1 |
| 14 | Reactome:a knowledge base of biologic pathways and processes显示文摘 | Imre V Peter D Esther S | 2007 | Genome Biology2007，8，3： | 1 |
| 15 | Synthesis and structural and photocatalytic properties of TiO 2 /montmorillonite nanocomposites显示文摘 | Robert Kun Károly Mogyorósi Imre Dékány | 2005 | Applied Clay Science2005，，1： | 1 |
| 16 | Ozone production in the New York City urban plume显示文摘 | Kleinman L I Danm P H Imre D G | 2000 | J Geophys Res2000，105，14： | 1 |
| 17 | Optimal production-inventory strategies for a HMMS-type reverse Iogistics system显示文摘 | IMRE D | 2003 | International Journal of Production Economics2003，81，： | 1 |
| 18 | Ammonia: Dynamical modeling of the absorption spectrum显示文摘 | Tang S L Imre D G Tannor D | 1990 | Journal of Chemical Physis1990，92，10： | 1 |
| 19 | Determination of loratadine and its active metabolite in human plasma by high performance liquid chromatography with mass spectrometry detection显示文摘 | VLASE L IMRE S MUNTEAN D | 2006 | Pharm Biomed Anal2006，，： | 1 |
| 20 | Ozone production rate and hydrocarbon reactivity in 5 urban areas: A cause of high ozone concentration in Houston 显示文摘 | KLEINMAN L I DAUM P H IMRE D | 2002 | Geophysical Research Letters2002，29，10： | 1 |
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