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| 1 | Experimental obstructive jaundice alters claudin-4 expression in intestinal mucosa: Effect of bombesin and neurotensin显示文摘瞄准:调查试验性的妨碍的黄疸和外长的 bombesin 和 neurotensin (NT )(BBS ) 的影响紧密的连接(TJ ) 的表示上的管理在老鼠的肠上皮的蛋白质 claudin-4。方法:四十只男 Wistar 老鼠随机被划分成五个组:我 = 控制, II = 假冒操作, III = 胆汁管结扎(BDL ) , IV = BDL+BBS (30 microg/kg 每 d ) , V = BDL+NT (300 microg/kg 每 d ) 。在 d 的实验的结束 10,内毒素在门和大动脉的血被测量。终端回肠的织物节组织学地被检验并且免疫组织化学地为在肠上皮的 claudin-4 表示的评估。结果:妨碍的黄疸导致了重要的门和大动脉的 endotoxemia 表明的肠的障碍失败。Claudin-4 表示显著地被增加在上面在 jaundiced 老鼠的第三根绒毛并且一起来它的侧面的分发的规定被注意。BBS 或 NT 的管理恢复了 claudin-4 表示到控制状态并且显著地减少了门和大动脉的 endotoxemia。结论:在肠上皮的试验性的妨碍的黄疸增加 claudin-4 表示,它可以是贡献粘膜障碍的混乱的一个关键因素。毁坏规章的肽 BBS, NT 能阻止这扇改变和还原剂门和全身的 endotoxemia。 | Stelios F Assimakopoulos Constantine E Vagianos Aristides S Charonis Ilias H Alexandris Iris Spiliopoulou Konstantinos C Thomopoulos Vassiliki N Nikolopoulou Chrisoula D Scopa | 2006 | World Journal of Gastroenterology2006，12，21： | 21 |
| 2 | 根据血压等级确定脑卒中和冠状动脉粥样硬化性心脏病死亡的终生风险:日本EPOCH(观察队列的心血管预防证据)研究显示文摘在亚洲人群中.很少研究关注根据血压分类确定脑卒中和冠状动脉粥样硬化性心脏病(coronary heartdisease,CHD)的终生风险。该研究旨在用一个包含个体参与者数据的荟萃分析大数据库来评估它。该荟萃分析纳入来源于13个队列的107 737名日本人(男性占42.4%,平均年龄55.1岁)。在平均(15.2±5.3)年(1 559 136人年)的随访期.1922人死于脑卒中,913人死于CHDO研究者在调整其他死亡危险因素后估计风险。 | 陈嘉睿(译) 练桂丽(审校) Satoh M Ohkubo T Asayama K Murakami Y Sugiyama D Yamada M Saitoh S Sakata K Irie F Sairenchi T Ishikawa S Kiyama M Ohnishi H Miura K Imai Y Ueshima H Okamura T EPOCH-JAPAN research group | 2019 | 中华高血压杂志2019，27，4： | 9 |
| 3 | SPQD14120800011178显示文摘 | Kordes Claus Sawitza Iris G?tze Silke Herebian Diran H?ussinger Dieter | 2014 | Journal of Clinical Investigation2014，，12： | 2 |
| 4 | Optimal MR cholangiopancreatographic sequence and its clinical application显示文摘 | Irie H Honda H Tajima T | 1998 | Radiology1998，206，2： | 1 |
| 5 | Metabolic engineering of astaxanthin production in tobacco flowers显示文摘 | VARDA M MARK H IRIS P | 2000 | Nat Biotechnol2000，18，： | 1 |
| 6 | Optimal MR cholangiopancreatogrphic sequence and its clinical application显示文摘 | Honda H Kuroiwa T | 1998 | Radiology1998，206，2： | 1 |
| 7 | Increased proliferative activity caused by loss of p21(WAF1/CIP1)expression and its clinical significance in patients with early-stage gastric significant carcinoma显示文摘 | Lacham Y Irie K | 2002 | Cancer2002，94，7： | 1 |
| 8 | Metastable liquid separation in underconled Fe- Cu and Fe- Cu- Si melts containing a small B concentration and their solidification structure显示文摘 | Yamauchi I Irie T Sakaguchi H | 2005 | Journal of Alloys and Compounds2005，403，： | 1 |
| 9 | In vivo measurement of acetylcholinesterase activity in the brain with a radioactive acetylcholine analog显示文摘 | Namba H Irie T Fukushi K | 1994 | Brain Res1994，667，： | 1 |
| 10 | Genetic parameter estimates of meat quality traits in Duroc pigs selected for average daily gain, longissimus muscle area, backfat thickness, and intramuscular fat content显示文摘 | Suzuki K Irie M Kadowaki H | 2005 | Animal Science2005，，83： | 1 |
| 11 | Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways 显示文摘 | Nishida E Irie K | 1997 | Science1997，275，5296： | 1 |
| 12 | Trunk muscle strength and disability level of low back pain in collegiate wrestlers显示文摘 | Iwai K Nakazato K Irie K Fujimoto H Nakajima H | | Med Sci Sports Exerc0，36，8： | 1 |
| 13 | Suppressing effect of CaCO3 on the dioxins emission from poly (vinyl chloride) (PVC)incineration显示文摘 | Sun R D Irie H Nishikawa T | 2003 | Polymer Degradation and Stability2003，79，2： | 1 |
| 14 | Preference toward a T-helper 1 response in patients with coronary spastic angina显示文摘 | Irie A Miyamoto S | 2003 | Circulation2003，107，： | 1 |
| 15 | Molded bone augmentation by a combination of barrier membrane and recombinant human bone morphogenetic protein 2显示文摘 | Takeishi H Irie K Okuda K | 2001 | Oral Dis2001，7，5： | 1 |
| 16 | Brain acetylcholinesterase activity: validation of a PET tracer in a rat model of Alzheimer's disease显示文摘 | Irie T Fukushi K Namba H | 1996 | J Nucl Med1996，37，： | 1 |
| 17 | Reconstruction of cartilage tissue using scaffold-free organoid culture technique显示文摘 | Irie Y Mizumoto H Fujino S | | 0，，： | 1 |
| 18 | Trapezoidal modulating signal for three-phase PWM inverter显示文摘 | Taniguchi K Irie H | 1986 | IEEE Transactions on Industrial Electronics1986，33，2： | 1 |
| 19 | 查看详情显示文摘 | Irie H Watanabe Y Hashimoto K | | 0，，： | 1 |
| 20 | Nitrogen-concentration dependence on photo-catalytic activity of TiO2-xNx powders显示文摘 | Irie H Hashimoto K | 2003 | J Phys Chem B2003，107，23： | 1 |
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