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| 1 | Picodetermination of microcystins in natural blooms and cyanobacterial strain cultures by matrix solid-phase disperseion and liquid chromatography-mass spectrometry显示文摘 | ANA C N ISABE M MORENO M A J | 2004 | Anal Bioanal Chem2004，380，： | 1 |
| 2 | Pyrolysis of scrap tyres显示文摘 | Isabal M R Lares goiti M F Cabrero M A | 2001 | Fuel Processing Technology2001，72，： | 1 |
| 3 | Synthesis and characterization of thiolate-Ag(I) complexes by solid-state and solution NMR and their antimicrobial activity显示文摘 | Anvarhusein A Isab Mohammed I M Wazeer | 2007 | Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy2007，66，2： | 1 |
| 4 | Pyrolysis of scrap tires显示文摘 | Isabal M R Lares goiti M F Cabrero M A | 2001 | Fuel Processing Technology2001，72，： | 1 |
| 5 | New cadmium chloride complexes with imidazolidine-2-thione and its derivatives: X-ray structures, solid, state and solution NMR and antimierobial activity studies显示文摘 | Wazeer M I M Isab A A Fettouhi M | 2007 | Polyhedron2007，26，8： | 1 |
| 6 | Determination of microcystins in natural blooms and cyanobacterial strain cultures by matrix solid-phase dispersion and liquid chromatography mass spectrometry显示文摘 | ANA C N ISABE M MORENO M A J | 2004 | Analytical and Bioanalytical Chemistry2004，380，3： | 1 |
| 7 | Method to quantify live and dead cells in multi - species oral hiofilm by real - time PCR with propidium monoazide 显示文摘 | ALVAREZ G GONZALEZ M ISABAL S | 2013 | AMB Express2013，3，1： | 1 |
| 8 | Chemical composition, antiparasitic and cytotoxic activities of aqueous extracts of Ziziphus joazeiro Mart显示文摘Objective: To compare the in vitro antiparasitic activity of aqueous extracts from Ziziphus joazeiro leaves and stem bark against Trypanosoma cruzi, Leishmania braziliensis, and Leishmania infantum, as well as to evaluate its cytotoxicity in mammalian cells, in addition to identifying the chemical composition of the extracts. Methods: Ziziphus joazeiro leaf and stem bark aqueous extracts were prepared by cold extraction maceration and subjected to ultra-efficient liquid chromatography coupled to a quadrupole/time of flight system. The susceptibility assays used Trypanosoma cruzi CLB5 strains and promastigote forms of Leishmania braziliensis and Leishmania infantum for antiparasitic activity of the extracts. Moreover, mammalian fibroblasts NCTC clone 929 were used for cytotoxicity analysis. Results: Terpenoid compounds, flavonoids and phenolic acid were identified in extracts. The stem bark aqueous extracts presented more significant results in terms of antiparasitic activity compared with the leaf aqueous extracts, especially against Leishmania braziliensis and Leishmania infantum promastigote forms with an IC50 < 500 μg/mL. The cytotoxicity evaluation showed moderate toxicity of the stem bark aqueous extracts, which is relevant information for the rational use of this plant part since it is widely used by the population. Conclusions: These preliminary results may contribute to the formulation of new therapeutic agents against this group of neglected diseases, so further investigations are required to delineate the mechanisms of action mainly of the aqueous extract of stem bark of Ziziphus joazeiro. | Jacqueline Cosmo ANDrade Ana Raquel Pereira da Silva Ant?nia Thassya Lucas dos Santos Maria Audilene Freitas Yedda Maria Lobo Soares de Matos Maria Flaviana Bezerra Morais Braga Camila Fonseca Bezerra Maria Isabeli Pereira Gon?alo Maria Celeste Vega Gomez Míriam Rolóm Cathia Coronel Paulo Riceli Vasconcelos Ribeiro Edy Sousa de Brito Henrique Douglas Melo Coutinho | 2019 | Asian Pacific Journal of Tropical Biomedicine2019，9，5： | 0 |
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