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7篇 您的检索式：作者名="Ian Penman"

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		题名	作者	年代	出处	被引量
	1	Radiofrequency ablation for early oesophageal squamous neoplasia:Outcomes form United Kingdom registry显示文摘AIM:To report outcomes on patients undergoing radiofrequency ablation(RFA)for early oesophageal squamous neoplasia from a National Registry.METHODS:A Prospective cohort study from 8 tertiary referral centres in the United Kingdom.Patients with squamous high grade dysplasia(HGD)and early squamous cell carcinoma(ESCC)confined to the mucosa were treated.Visible lesions were removed by endoscopic mucosal resection(EMR)before RFA.Following initial RFA treatment,patients were followed up 3monthly.Residual flat dysplasia was treated with RFA until complete reversal dysplasia(CR-D)was achieved or progression to invasive Squamous cell cancer defined as infiltration into the submucosa layer or beyond.The main outcome measures were CR-D at 12 mo from start of treatment,long term durability,progression to cancer and adverse events.RESULTS:Twenty patients with squamous HGD/ESCC completed treatment protocol.Five patients(25%)had EMR before starting RFA treatment.CR-D was 50%at12 mo with a median of 1 RFA treatment,mean 1.5(range 1-3).Two further patients achieved CR-D with repeat RFA after this time.Eighty per cent with CR-D remain dysplasia free at latest biopsy,with median follow up 24 mo(IQR 17-54).Six of 20 patients(30%)progressed to invasive cancer at 1 year.Four patients(20%)required endoscopic dilatations for symptomatic structuring after treatment.Two of these patients have required serial dilatations thereafter for symptomatic dysphagia with a median of 4 dilatations per patient.The other 2 patients required only a single dilatation to achieve an adequate symptomatic response.One patient developed cancer during follow up after end of treatment protocol.CONCLUSION:The role of RFA in these patients re-mains unclear.In our series 50%patients responded at12 mo.These figures are lower than limited published data.	Rehan J Haidry Mohammed A Butt Jason Dunn Matthew Banks Abhinav Gupta Howard Smart Pradeep Bhandari Lesley Ann Smith Robert Willert Grant Fullarton Morris John Massimo Di Pietro Ian Penman Marco Novelli Laurence B Lovat	2013	World Journal of Gastroenterology2013，19，36：	7
	2	Review of screening for pancreatic cancer in high risk individuals显示文摘Pancreatic cancer is difficult to diagnose at an early stage and is associated with a very poor survival.Ten percent of pancreatic cancers result from genetic susceptibility and/or familial aggregation.Individuals from families with multiple affected first-degree relatives and those with a known cancer-causing genetic mutation have been shown to be at much higher risk of developing pancreatic cancer.Recent efforts have focused on detecting disease at an earlier stage to improve survival in these high-risk groups.This article reviews high-risk groups,screening methods,and current screening programs and their results.	Alina Stoita Ian D Penman David B Williams	2011	World Journal of Gastroenterology2011，17，19：	4
	3	Basic technique for celiac plexus block/neurolysis显示文摘	Ian D. Penman David Gilbert	2009	Gastrointestinal Endoscopy2009，，：	1
	4	EUS 2008 Working Group document : evaluation of EUS-guided celiac plexus neurolysis/block( with video) 显示文摘	IAN D PENMAN THOMAS P	2009	Gastrointest Endosc2009，69，2：	1
	5	EUS in advanced esophageal cancer显示文摘	Ian D. Penman Emily F. Shen	2002	Gastrointestinal Endoscopy2002，，：	1
	6	An examination of subgroup classification in irritable bowel syndrome patients over time: A prospective study显示文摘	Kay I. Penny Graeme D. Smith David Ramsay Douglas T. Steinke Moira Kinnear Ian D. Penman	2008	International Journal of Nursing Studies2008，，12：	1
	7	Radiofrequency Ablation and Endoscopic Mucosal Resection for Dysplastic Barrett’s Esophagus and Early Esophageal Adenocarcinoma: Outcomes of the UK National Halo RFA Registry显示文摘	Rehan J. Haidry Jason M. Dunn Mohammed A. Butt Matthew G. Burnell Abhinav Gupta Sarah Green Haroon Miah Howard L. Smart Pradeep Bhandari Lesley Ann Smith Robert Willert Grant Fullarton John Morris Massimo Di Pietro Charles Gordon Ian Penman Hugh Barr Praf	2013	Gastroenterology2013，，1：	1

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