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| 1 | Continuous vagus nerve stimulation effects on the gut-brain axis in swine显示文摘 | Idoia D Francisco M Sánchez L | 2007 | Neuromodulatlon:technology at the neural interface2007，，1： | 1 |
| 2 | Tonometry as a predictor of inadequate splanchnic perfusion in an intra-abdominal hypertension animal model显示文摘 | Laura Correa-Martín Gregorio Castellanos Mónica García-Lindo Idoia Díaz-Güemes Francisco M. Sánchez-Margallo | 2013 | Journal of Surgical Research2013，，： | 1 |
| 3 | Cardiotrophin-1 in hypertensive heart disease显示文摘 | Arantxa González Bego?a López Susana Ravassa Javier Beaumont Amaia Zudaire Idoia Gallego Cristina Brugnolaro Javier Díez | 2012 | Endocrine2012，，1： | 1 |
| 4 | 时间趋势、环境因素和遗传基础特性对商业条件下荷斯坦公牛精液性状的影响显示文摘人工受精(AI)的结果是降低已经进行过高度选择雄性繁殖力评价的奶牛种群数量。1990-2007年采集502头荷斯坦公牛的42348个精液数据进行贝叶斯框架分析,对过去十几年在人工受精中心常规收集的精液进行精液特征进化和遗传参数的评估。主要考虑的特性是精子数量(VOL)、浓度(CONC)、每次射精的精子数量(NESPZ)、总体精子活力(MM)、个体精子活力(IM)以及解冻后活力(PTM)。研究环境因素随时间的变化时,根据环境和技术条件的改变,年龄的变化、射精顺序、提前收集的时间点(TPC)以及收集和冻结期间的时间点(TCF)对其进行每季度和每周的收集,公牛近交系数(Fi)、永久环境和添加剂遗传因素也被考虑在内,运用贝叶斯因子对此降低模型的使用进行评价。在该模型中对所有的系统效应进行测试并除了Fi影响精子活性和TCF影响PTM之外,得出有力的数据证明模型的正确性。观察中发现除PTM外,环境影响没有系统时间的趋势,这表明环境改变的趋势参与精子冻融的改善。遗传力评价除IM外均处于中度(0.16-0.22),其中存在一个低值(0.07)。精子之间活力的相互作用以及精子活力与CONC之间的相互作用存在较大的遗传相关性(0.38-0.87),VOL与CONC显示出负相关性(-0.13)。如果要求使用这些特征作为判断公牛育种精子活力的指标,需要增大遗传性能有效的选择。 | Sofiene K Clara D Magdalena S Roger C Idoia C María J C | 2011 | 饲料博览2011，，9： | 1 |
| 5 | Acute liver failure secondary to acute antibody mediated rejection after compatible liver transplant: A case report显示文摘BACKGROUND The liver has traditionally been regarded as resistant to antibody-mediated rejection(AMR).AMR in liver transplants is a field in its infancy compared to kidney and lung transplants.In our case we present a patient with alpha-1-antitrypsin disease who underwent ABO compatible liver transplant complicated by acute liver failure(ALF)with evidence of antibody mediated rejection on allograft biopsy and elevated serum donor-specific antibodies(DSA).This case highlights the need for further investigations and heightened awareness for timely diagnosis.CASE SUMMARY A 56 year-old woman with alpha-1-antitrypsin disease underwent ABO compatible liver transplant from a deceased donor.The recipient MELD at the time of transplant was 28.The flow cytometric crossmatches were noted to be positive for T and B lymphocytes.The patient had an uneventful recovery postoperatively.Starting on postoperative day 5 the patient developed fevers,elevated liver function tests,distributive shock,renal failure,and hepatic encephalopathy.She went into ALF with evidence of antibody mediated rejection with portal inflammation,bile duct injury,endothelitis,and extensive centrizonal necrosis,and C4d staining on allograft biopsy and elevated DSA.Despite various interventions including plasmapheresis and immunomodulating therapy,she continued to deteriorate.She was relisted and successfully underwent liver retransplantation.CONCLUSION This very rare case highlights AMR as the cause of ALF following liver transplant requiring retransplantation. | Todd J Robinson James B Hendele Idoia Gimferrer Nicolae Leca Scott W Biggins Jorge D Reyes Lena Sibulesky | 2022 | World Journal of Hepatology2022，14，1： | 0 |
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