|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Comparison of constrained sparse spike and stochastic inversion for porosity prediclion at Kristin Field 显示文摘 | Jan H Ingrid M Sarah P | 2000 | The Leading Edge2000，19，4： | 1 |
| 2 | Acute endophthalmitis following intravitreal triamcinolone acetonide injection显示文摘 | Darius M Moshfeghi Peter K Kaiser Ingrid U Scott Jonathan E Sears Matthew Benz Juan P Sinesterra Richard S Kaiser Sophie J Bakri Raj K Maturi Jonathan Belmont Paul M Beer Timothy G Murray Hugo Quiroz-Mercado William F Mieler | 2003 | American Journal of Ophthalmology2003，，5： | 1 |
| 3 | Journal club: acute abdominal pain in elderly patients : effect of radiologist awareness of clinicobiologic information on CT accuracy显示文摘 | Ingrid M Chakib A Emmanuelle B P | 2013 | American Journal of Roentgenology2013，201，6： | 1 |
| 4 | Independent effects of diet and exercise training on fat oxidation in non-alcoholic fatty liver disease显示文摘AIM To investigate the independent effects of 6-mo of dietary energy restriction or exercise training on wholebody and hepatic fat oxidation of patients with nonalcoholic fatty liver disease(NAFLD).METHODS Participants were randomised into either circuit exercise training(EX;n = 13;3 h/wk without changes in dietary habits),or dietary energy restriction(ER) without changes in structured physical activity(ER;n = 8).Respiratory quotient(RQ) and whole-body fat oxidation rates(Fatox) were determined by indirect calorimetry under basal,insulin-stimulated and exercise conditions.Severity of disease and steatosis was determined by liver histology;hepatic Fatox was estimated from plasma β-hydroxybutyrate co.ncentrations;cardiorespiratory fitness was expressed as VO2 peak.Complete-case analysis was performed(EX:n = 10;ER:n = 6).RESULTS Hepatic steatosis and NAFLD activity score decreased with ER but not with EX.β-hydroxybutyrate concentrations increased significantly in response to ER(0.08 ± 0.02 mmol/L vs 0.12 ± 0.04 mmol/L,P = 0.03) but remained unchanged in response to EX(0.10 ± 0.03 mmol/L vs 0.11 ± 0.07 mmol/L,P = 0.39).Basal RQ decreased(P = 0.05) in response.to EX,while this change was not significant after ER(P = 0.38).VO_(2peak)(P < 0.001) and maximal Fa_(tox) during aerobic exercise(P = 0.03) improved with EX but not with ER(P > 0.05).The increase in β-hydroxybutyrate concentrations was correlated with the reduction in hepatic steatosis(r =-0.56,P = 0.04).CONCLUSION ER and EX lead to specific benefits on fat metabolism of patients with NAFLD.Increased hepatic Fat_(ox) in response to ER could be one mechanism through which the ER group achieved reduction in steatosis. | Ilaria Croci Nuala M Byrne Veronique S Chachay Andrew P Hills Andrew D Clouston Trisha M O'Moore-Sullivan Johannes B Prins Graeme A Macdonald Ingrid J Hickman | 2016 | World Journal of Hepatology2016，8，27： | 1 |
| 5 | Acute endophthalmitis following intravitreal triamcinolone acetonide injection显示文摘 | Darius M Moshfeghi Peter K Kaiser Ingrid U Scott Jonathan E Sears Matthew Benz Juan P Sinesterra Richard S Kaiser Sophie J Bakri Raj K Maturi Jonathan Belmont Paul M Beer Timothy G Murray Hugo Quiroz-Mercado William F Mieler | 2003 | American Journal of Ophthalmology2003，，5： | 1 |
| 6 | Severe, very early onset preeclampsia: Subsequent pregnancies and future parental cardiovascular health显示文摘 | Ingrid P M Gaugler-Senden Anne L | 2008 | Ejog2008，，140： | 1 |
| 7 | Severe, very early onset preeclampsia: Subsequent pregnancies and future parental cardiovascular health 显示文摘 | Ingrid P M Gaugler - Senden | 2008 | European Journal of Obstetrics & Gynecology and Reproductive Biology2008，140，2： | 1 |
| 8 | Medical management of BPH : Role of Plant Extracts 显示文摘 | Stephan M Anton P Ingrid B | 2007 | European Association of Urology2007，，： | 1 |
| 9 | Maternal and perinatal outcome of preeclampsia with an onset before 24 weeks' gestation Audit in a tertiary referral center显示文摘 | Ingrid P M Gaugler S Annemarie G H | 2006 | European Journal of Obstetrics & Gynecology and Reproductive Biology2006，128，： | 1 |
| 10 | Similarity of differently sized macro-aggregates in arable soils of different texture 显示文摘 | Spren M K Schjcpnning P Ingrid K | 2006 | Geoderma2006，137，： | 1 |
| 11 | Aqueous extracts from some muscle inhibit hemoglobin-mediated oxidation of cod muscle membrane lipids显示文摘 | RICHARDS M P INGRID U HULTIN H O | 2003 | Journal of Agricultural and Food Chemistry2003，51，： | 1 |
| 12 | Silicone oil in the repair of complex retinal detachments显示文摘 | Stanley P Azen Ingrid U Scott Harry W Flynn Mei-Ying Lai Trexler M Topping Lisa Benati Douglas K Trask Lee Ann Rogus | 1998 | Ophthalmology1998，，9： | 1 |
| 13 | Minocycline fails to improve neurologic and histologic outcome after ventricular fibrillation cardiac arrest in rats显示文摘BACKGROUND Prolonged cardiac arrest(CA)produces extensive neuronal death and microglial proliferation and activation resulting in neuro-cognitive disabilities.Among other potential mechanisms,microglia have been implicated as triggers of neuronal death after hypoxic-ischemic insults.Minocycline is neuroprotective in some brain ischemia models,either by blunting the microglial response or by a direct effect on neurons.AIM To improve survival,attenuate neurologic deficits,neuroinflammation,and histological damage after ventricular fibrillation(VF)CA in rats.METHODS Adult male isoflurane-anesthetized rats were subjected to 6 min VF CA followed by 2 min resuscitation including chest compression,epinephrine,bicarbonate,and defibrillation.After return of spontaneous circulation(ROSC),rats were randomized to two groups:(1)Minocycline 90 mg/kg intraperitoneally(i.p.)at 15 min ROSC,followed by 22.5 mg/kg i.p.every 12 h for 72 h;and(2)Controls,receiving the same volume of vehicle(phosphate-buffered saline).The rats were kept normothermic during the postoperative course.Neurologic injury was assessed daily using Overall Performance Category(OPC;1=normal,5=dead)and Neurologic Deficit Score(NDS;0%=normal,100%=dead).Rats were sacrificed at 72 h.Neuronal degeneration(Fluoro-Jade C staining)and microglia proliferation(anti-Iba-1 staining)were quantified in four selectively vulnerable brain regions(hippocampus,striatum,cerebellum,cortex)by three independent reviewers masked to the group assignment.RESULTS In the minocycline group,8 out of 14 rats survived to 72 h compared to 8 out of 19 rats in the control group(P=0.46).The degree of neurologic deficit at 72 h[median,(interquartile range)]was not different between survivors in minocycline vs controls:OPC 1.5(1-2.75)vs 2(1.25-3),P=0.442;NDS 12(2-20)vs 17(7-51),P=0.328)or between all studied rats.The number of degenerating neurons(minocycline vs controls,mean±SEM:Hippocampus 58±8 vs 76±8;striatum 121±43 vs 153±32;cerebellum 20±7 vs 22±8;cortex 0±0 vs 0±0)or proliferating microglia(hippocampus 157±15 vs 193 cortex 0±0 vs 0±0;16;striatum 150±22 vs 161±23;cerebellum 20±7 vs 22±8;cortex 26±6 vs 31±7)was not different between groups in any region(all P>0.05).Numerically,there were approximately 20%less degenerating neurons and proliferating microglia in the hippocampus and striatum in the minocycline group,with a consistent pattern of histological damage across the individual regions of interest.CONCLUSION Minocycline did not improve survival and failed to confer substantial benefits on neurologic function,neuronal loss or microglial proliferation across multiple brain regions in our model of rat VF CA. | Andreas Janata Ingrid AM Magnet Kristin L Schreiber Caleb D Wilson Jason P Stezoski Keri Janesko-Feldman Patrick M Kochanek Tomas Drabek | 2019 | World Journal of Critical Care Medicine2019，8，7： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员