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264篇 您的检索式:作者名="Injury"
    题名 作者 年代 出处 被引量
1脊髓损伤神经学分类国际标准(2011年修订)显示文摘本手册内容为脊髓损伤神经学分类国际标准(ISNCSCI)第7版,该标准描述了脊髓损伤的查体方法(即国际标准查体方法)及美国脊髓损伤协会(ASIA)残损分级。基于世界各国脊髓损伤治疗和研究领域的临床医师和研究人员的意见、问题和建议,本标准对一些概念和表达进行了澄清和修订。关于ISNCSCI某些问题的澄清已经在最近发表的一些论文中进行详细阐述。另外,所做出的修订也尽可能与InSTeP培训项目保持一致。委员会对修订采取了审慎的态度,主要是考虑到重大修订应有循证学基础。American Spinal Injury Association International Spinal Cord Society 李建军 王方永(译) 2011中国康复理论与实践2011,17,10:401
2Differentially expressed proteins of gamma-ray irradiated mouse intestinal epithelial cells by two-dimensional electrophoresis and MALDI-TOF mass spectrometry显示文摘AIM: To identify the differentially expressed proteins involved in ionizing radiation in mice and to explore new ways for studying radiation-related proteins.METHODS: Bal B/c mice grouped as sham-irradiation, 3h and 72 h irradiation were exposed to 9.0Gy single dose of γ-irradiation. Intestinal epithelia were isolated from mice,and total proteins were extracted with urea containing solution. A series of methods were used, including twodimensional electrophoresis, PDQuest 2-DE software analysis, peptide mass fingerprinting based on matrixassisted laser desorption/ionization time of flight masss pectrometry (MALDI-TOF-MS) and SWISS-PROT database searching, to separate and identify the differential proteins.Western blotting and RT-PCR were used to validate the differentially expressed proteins.RESULTS: Mouse intestine was severely damaged by 9.0 Gy γ-irradiation. Image analysis of two-dimensional gels revealed that averages of 638±39, 566±32 and 591±29 protein spots were detected in 3 groups, respectively, and the majority of these protein spots were matched. About 360 protein spots were matched between normal group and 3 h irradiation group, and the correlation coefficient was 0.78 by correlation analysis of gels. Also 312 protein spots matched between normal group and 72 h irradiation group, and 282 protein spots between 3 h and 72 h irradiation groups. Twenty-eight differential protein spots were isolated from gels, digested with trypsin, and measured with MALDI-TOF-MS. A total of 25 spots yielded good spectra, and 19 spots matched known proteins after database searching. These proteins were mainly involved in anti-oxidation, metabolism, signal transduction,and protein post-translational processes. Western-blotting confirmed that enolase was up-regulated by γ-irradiation. Up-regulation of peroxiredoxin I was verified by applying RTPCR technique, but no change occurred in QSVC72.CONCLUSION: These differentially expressed proteins might play important roles when mouse intestine was severely injured by γ-irradiation. It is suggested that differential proteomic analysis may be a useful tool to study the proteins involved in radiation damage of mouse intestinal epithelia.Bo Zhang Yong-Ping Su Guo-Ping Ai Xiao-Hong Liu Feng-Chao Wang Tian-Min Cheng Institute of Combined Injury of PLA,Third Military Medical University,Chongqing 400038,China 2003World Journal of Gastroenterology2003,9,12:10
3A Feasibility Study of FES Restoration of Elbow Movementsfor C5/C6 Quadriplegic Patients显示文摘This paper presents a feasibility study of restoration of elbow movements in C5/C6quadriplegic patientS by functional electrical stimulation (FES). A biomechanical model of thebiceps and triceps muscles and elbow joint is developed for computer simulation. A feedbackcontrol method is evaluated in the study for the static and dynamic responses. Results indicate thatit is possible to achieve extension control at the elbow joint with electrical stimulation of extensormuscle. These results may provide a plausible control method for controlling elbow extensionmovements in clinical application.N. Lan J.C. Wang P. Lin and Y. Li(Dept. of Electrical Engineering, Tsinghua UniversityBeijing 100084, P. R. China)(Spinal Cord injury Unit, Charity HospitalChina Rehabilitation Research Center, Beijing 100077, P. R. China) 1998Chinese Journal of Biomedical Engineering(English Edition)1998,7,3:6
4脾外伤保脾手术95例报告显示文摘目的:恢复脾外伤患者的脾功能,提高其生存质量。方法:对95例脾外伤(外伤分级Ⅰ~Ⅴ级)实施保脾手术,其中20例单纯修补,53例选用脾部分切除(其中13例附加修补,1例附加成形),4例保留副脾,18例行自体脾组织移植。结果:原位保脾77例,占81%,其中保脾量≥1/2脾63例,占原位保脾组81.8%,占全组66.3%。脾片移植18例,占18.9%。治愈94例,死亡1例,治愈率98.9%。结论:采用脾血流控制技术是提高脾外伤保脾手术质量的前提。根据脾损伤部位、严重程度及裂伤深度选择保脾术式是提高保脾手术质量的关键。The Splenic Injury Study Group in the Northwest of Sichuan 1997中国冶金工业医学杂志1997,14,2:4
5Modulating autophagy:a strategy for cancer therapy显示文摘Autophagy is a process in which long-lived proteins,damaged cell organelles,and other cellular particles are sequestered and degraded.This process is important for maintaining the cellular microenvironment when the cell is under stress.Many studies have shown that autophagy plays a complex role in human diseases,especially in cancer,where it is known to have paradoxical effects.Namely,autophagy provides the energy for metabolism and tumor growth and leads to cell death that promotes tumor suppression.The link between autophagy and cancer is also evident in that some of the genes that regulate carcinogenesis,oncogenes and tumor suppressor genes,participate in or impact the autophagy process.Therefore,modulating autophagy will be a valuable topic for cancer therapy.Many studies have shown that autophagy can inhibit the tumor growth when autophagy modulators are combined with radiotherapy and/or chemotherapy.These findings suggest that autophagy may be a potent target for cancer therapy.Jun-Lin Li1,Shao-Liang Han2 and Xia Fan3 1Department of General Surgery,The Central Hospital of Yongzhou City,Yongzhou,Hunan 425000,P.R.China 2Department of General Surgery,First Affiliated Hospital of Wenzhou Medical College,Wenzhou,Zhejiang 325000,P.R.China 3State Key Laboratory of Trauma,Burns,and Combined Injury Research Institute of Surgery,Daping Hospital,Third Military Medical University,Chongqing 400042,P.R.China. 2011Chinese Journal of Cancer2011,30,10:3
6Guidelines for management of pediatric acute hyperextension spinal cord injury显示文摘Pediatric acute hyperextension spinal cord injury(SCI)named as PAHSCI by us,is a special type of thoracolumbar SCI without radiographic abnormality and highly related to back-bend in dance training,which has been increasingly reported.At present,it has become the leading cause of SCI in children,and brings a heavy social and economic burden.Both domestic and foreign academic institutions and dance education organizations lack a correct understanding of PAHSCI and relevant standards,specifications or guidelines.In order to provide standardized guidance,the expert team formulated this guideline based on the principles of science and practicability,starting from the diagnosis,differential diagnosis,etiology,admission evaluation,treatment,complications and prevention.This guideline puts forward 23 recommendations for 14 related issues.Lian Zeng Yu-Long Wang Xian-Tao Shen Zhi-Cheng Zhang Gui-Xiong Huang Jamal Alshorman Tracy Boakye Serebour Charles H.Tator Tian-Sheng Sun Ying-Ze Zhang Xiao-Dong Guo on behalf of Chinese Orthopaedic Association,Spinal Cord Injury and Rehabilitation Group,Chinese Association of Rehabilitation Medicine,Group of Spinal Injury and Functional Reconstruction,Neuroregeneration&Neurorestoration Professional Committee,Association of Chinese Research Hospital,Sino-Canada Spinal and Spinal Cord Injury Center 2023Chinese Journal of Traumatology2023,26,1:2
7Clinical assessment after acute cervical spinal cord injury 显示文摘American Spinal Injury Association 2002Neurosurgery2002,50,3:1
8The Acute Respiratory Distress Syndrome Network显示文摘Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome 2000N Engl J Med2000,342,18:1
9Assessment of injury to the thoracolumbar posterior ligamentous complex in the setting of normal-appearlng plain radiography显示文摘Using magnetic resonance injury to the posterior ligamen- a prospective comparison of the Neurosurg Spine 2010 12(4): Lee JY Vaccaro AR Schweitzer KM Jr 2007Spine J2007,7,4:1
10显示文摘LOWERYRB CALBOUNJH injury mechanism and classification FracturesOfthecalcaneus 1996FootAnklelnt1996,17,4:1
11KDIGO Clinical Practice Guideline for acute kidney injury显示文摘Kidney Disease Improving Global Outcomes KDIGOAcute Kidney Injury Work Group 0,,2:1
12显示文摘Ichimura T Bonventre JV Bailly V et aL Kidney injury molecule - ( KIM - 1 ) a putative epithelial eel1 adhesion molecule containing novel immunoglobulin domain is up- regulated in renal coils after it jury 1998J Biol Chem1998,273,7:1
13KDIGO clinical practice guideline for acute kidney injury 显示文摘Kidney Disease: Improving Global Outcomes (KDIGO) Ac- ute Kidney Injury Work Group 2012Kidney Int Suppl2012,,2:1
14Practice parameter:, antiepileptic drug treatment of posttraumatic seizures 显示文摘Brain Injury Special Interest Group of the American Academy of Physical Medicine and Rehabilitation 1998Arch Phys Med Rehabil1998,79,:1
15Human albumin administration in critical ill patients,systematic review of randomised controlled trials显示文摘Coehrane Injuries Group Albumin Reviewers 1998Br Med J1998,317,7153:1
16Results from the ALIVE study intensive 显示文摘Brun- Buisson C Minelli C Bertotini G et aI Epidemiology and outcome of acute lung injury in European in- tensive care units 2004Care Med2004,30,1:1
17Safe transportation of preterm and low birth weight infants at hospital discharge显示文摘Bull MJ Engle WA Committee on Injury V 2009Pediatrics2009,123,5:1
18Prevention of venous thromboembolism in the acute treatment phase after spinal cord injury:a randomized, multicenter trial comparing low-dose heparin plus intermittent pneumatic compression with enoxaparin显示文摘~ Spinal Cord Injury Thromboprophylaxis Investigators 2003J Trauma2003,54,6:1
19Clinical Practice Guideline forAcute Kidney Injury显示文摘Kidney Disease: Improving Global Outcomes (KDIGO) AcuteKidney Injury Work Group 2012Kidney Int Suppl2012,2,:1
20Human albumin administration in critically ill patients:systematic review of randomized controlled trials显示文摘Cochrane Injuries Group Albumin Reviewers 1998BMJ1998,317,7153:1
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