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| 1 | Determination of the gene structure of human GFAP and absence of coding region mutations associated with frontotemporal dementia with Parkinsonism linkedm to chromosome 17显示文摘 | Isaacs A Baker M Wavrant-De Vrieze F | 1998 | Genomics1998，，51： | 2 |
| 2 | Transcatheter aortic valve implantation in very elderly patients: immediate results and medium term follow-up显示文摘ObjectiveTo 评估立即的 transcatheter 在有严重、征兆的大动脉的狭窄的很老的病人的大动脉的阀门培植(TAVI ) 结果和中期的后续(作为).MethodsThis multicenter,观察、未来的学习在三所医院里被执行。我们包括了连续很老(>85 年) 病人与作为严重由 TAVI 对待。主要端点是在包括的二 years.ResultsThe 研究从任何原因评估死亡率有一个平均数的 160 个连续病人 87 ± 变老;2.1 年(从 85 ~ 94 年的范围) 和 18.8%± 的吝啬的逻辑 EuroSCORE;11.2% 与 57 (35.6%) 病人得分 ≥20% 。程序的成功率是 97.5% ,与 25 (15.6%) 与主要流血经历尖锐复杂并发症的病人(最经常) 。全球死亡率在住院期间是 8.8%(n = 14 ) 并且 30 天的死亡率是 10%(n = 16 ) 。中部在时期上面列在后面是 252.24 ±232.17 天。在后续时期期间, 28 (17.5%) 病人们死了(他们中的 17 个由于心脏的原因) 。估计的二年全面、心脏的幸存率使用 Kaplan-Meier 方法分别地是 71% 和 86.4% 。比例的危险回归给看了的考克斯可变 EuroSCORE ≥20 是与全面 mortality.ConclusionsTAVI 联系的唯一的变量在很老的病人的一张选择人口安全、有效。我们的调查结果支持在病人的这个复杂的组的这个新过程的采纳。 | Isaac Pascual Antonio J Mu oz-García Diego López-Otero Pablo Avanzas Manuel F Jimenez-Navarro Belén Cid-Alvarez Raquel del Valle Juan H Alonso-Briales Raimundo Ocaranza-Sanchez José M Hemández Ramiro Trillo-Nouche César Morís | 2015 | Journal of Geriatric Cardiology2015，12，4： | 1 |
| 3 | Blood Levels of Bicotine and Physiological Effects after Inhalation of Tobacco Smoke 显示文摘 | ISAAC P F RAND M J | 1969 | European Journal of Pharmacology1969，8，3： | 1 |
| 4 | Phase Ⅲ,randomized,double-blind,placebo-controlled multicenter trial of daily everolimus plus weekly trastuzumab and vinorelbine in trastuzumab-resistant,advanced breast cancer (BOLERO-3)显示文摘 | O' Regan R Ozguroglu M Andre F Toi M Jerusalem G Wilks S Isaacs C Xu B Masuda N Arena FP Yardley D Yap YS Mukhopadhyay P Douma S El-Hashimy M Taran T Sahmoud T Lebwohl D Gianni L | | 0，，15： | 1 |
| 5 | Association of ambient air pollution with respiratory hospitalization in a government designated 'area of concern': the case of Windsor, Ontario 显示文摘 | Isaac N L Karen Y F Kevin M G | 2005 | Environ Health Perspeet2005，113，3： | 1 |
| 6 | Early growth and nutritional response to resource competition in cocoa-shade intercropped systems显示文摘 | Isaac M E Ulzen-Appiah F Timmer V R | 2007 | Plant Soil2007，298，： | 1 |
| 7 | Blood levels of nicotine and physiological effects after inhalation of tobacco smoke显示文摘 | Isaac P F Rand M J | 1969 | European Journal of Pharmacology1969，，8： | 1 |
| 8 | Adult degenerative scoliosis treated with XLIF: clinical and radiographical results of a prospective multicenter study with 24-month follow-up 显示文摘 | Phillips F M Isaacs R E Rodgers W B | 2013 | Spine (Phila Pa 1976)2013，38，21： | 1 |
| 9 | Prediction of wind environment and thermal comfort at pedestrian level in urban area显示文摘 | Akashi M Isaac Y F | 2008 | Journal of Wind Engineering and Industrial Aerodynamic2008，96，1011： | 1 |
| 10 | Association of ambient air pollution with respiratory hospitalization in a government-designated 'area of concern':the case of Windsor,Ontario显示文摘 | Isaac N L Karen Y F Kevin M G | 2005 | Environmental Health Perspectives2005，113，3： | 1 |
| 11 | Mixed methods for complex kinematic constraints in dynamic figure animation 显示文摘 | Isaacs P M Cohen M F | 1988 | The Visual Computer1988，4，6： | 1 |
| 12 | Association of ambient air pollution with respiratory hospitalization in a government-designated 'area of concern' : the case of Windsor, Ontario显示文摘 | ISAAC N L KAREN Y F KEVIN M G | 2005 | Environ Health Perspect2005，113，3： | 1 |
| 13 | Coastal sub- marine hydrothermal activity off northern Baja California 显示文摘 | Vidal V M V Vidal F V Isaacs J D | 1978 | Journal of Geophysical Research1978，83，4： | 1 |
| 14 | Association of ambient air pollution with respiratory hospitaliza- tion in a government-designated 'area of concern': the case of Windsor, Ontario显示文摘 | Isaac N L Karen Y F Kevin M G | 2005 | Environ Health Perspect2005，113，2： | 1 |
| 15 | The reverse mortgage as an asset management tool显示文摘 | David W R Isaac F M Barbara A M | 1997 | Housing Policy Debate1997，8，1： | 1 |
| 16 | Electrochemical reduction of CO2 mediated by poly-M-aminophthalocyanines (M = Co,Ni,Fe):poly-Co-tetraaminophthalocyanine,a selective catalyst显示文摘 | Isaacs M Armijo F Ramfrez G | 2005 | Journal of Molecular Catalysis A:Chemical2005，229，： | 1 |
| 17 | Prediction of wind environment and thermal comfort at pedestrian level in urban area显示文摘 | A M Isaac Y F Lun | 2008 | Journal of Wind Engineering and Industrial Aerodynamics2008，96，： | 1 |
| 18 | Synthesis of ether- and carbon-linked polycarboranyl porphyrindimers for cancer therapies显示文摘 | Isaac M F Kahl S B | 2003 | J Organomet Chem2003，680，： | 1 |
| 19 | Desirer gene network:Towards funda- mental cellular control显示文摘 | Hasty J Isaacs F Dolnik M | 2001 | Chaos2001，11，1： | 1 |
| 20 | The effect of heat processing, gamma radiation, and ultraviolet radiation on the anaphylactogenic properties of milk 显示文摘 | KRAYBILL H F READ M S LINDER R O HARDING S ISAAC G J | 1959 | Journal of Allergy1959，30，4： | 1 |
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