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13篇 您的检索式:作者名="Iskander M N"
    题名 作者 年代 出处 被引量
1显示文摘ISLAM M N SONG Y ISKANDER M N 2003Journal of Molecular Graphics and Modelling2003,21,4:1
2Antiinflammatory screening of the medicinal plant Gynura procumbens显示文摘Iskander M N Song Y Coupar I M 2002Plant Foods for Human Nutrition2002,57,34:1
3Antiinflam- matory screening of the medicinal plant C, ynura procumbens 显示文摘Iskander M N Song Y Coupar I M 2002Plant Food Hum Nutr2002,57,34:1
4Sepsis : multiple abnormalities, heterogeneous responses, and evolving understanding 显示文摘Iskander K N Osuchowski M F Stearns-Kurosawa D J 2013Physiologic Rev2013,93,3:1
5Investigation of structural requirements of anticancer activity at the paclitaxel binding site using CoMFA and CoMSIA 显示文摘Islam M N Song Y Iskander M N 2003J Mol Graph Model2003,21,4:1
6Microstrip Array Antanna with New 2D-Electromagnetic Band Gap Structure Shapes to Reduce Harmonics and Mutual Coupling显示文摘ELSHEAKH D N ISKANDER M F 2010Progress in Electromagnetics Research C2010,,12:1
7Personalized Medicine in a Phase I Clinical Trials Program: The M D Anderson Cancer Center Initiative显示文摘Tsimberidou A M Iskander N G Hang D S 2012Clin Cancer Res2012,,:1
8FDTD simulation of microwave sintering of ceramics in multimode cavities显示文摘ISKANDER M D ANDRADE A O N M 1994IEEE Trans Microwave Theory and Techniques1994,42,5:1
9Synthesis of 3, 4-dihydro-3- ( p-methylphenyl )-1, 3-2 H-benzoxazine : An undergraduate organic chemistry experimenT显示文摘ISKANDER M N ANDREWS P R 1985J Chem Educ1985,62,10:1
10A convenient synthesis of α-benzylacrylic acid显示文摘Issa J Andrews P R Iskander M N 1995Syn Com1995,25,10:1
11Antiinflammatory screening of the medicinal plant Gynura procumbens显示文摘ISKANDER M N SONG Y COUPAR I M 2002Plant Foods Hum Nutr2002,57,34:1
12Bleehen theoretical analysis and clinical demonstration of the effect of power pattern control using the annular phased-array system 显示文摘Sathiaseclan V Iskander G C Howard N M 1998IEEE Trans Microwave Theory Tech1998,34,:1
13Monitoring adenoviral based gene delivery in rat glioma by molecular imaging显示文摘AIM:To determine whether endothelial progenitor cells(EPCs)can be used as delivery vehicle for adenoviral vectors and imaging probes for gene therapy in glioblastoma.METHODS:To use cord blood derived EPCs as delivery vehicle for adenoviral vectors and imaging probes for glioma gene therapy,a rat model of human glioma was made by implanting U251 cells orthotopically.EPCs were transfected with an adenovirus(AD5/carrying hNIS gene)and labeled with iron oxide and inoculated them directly into the tumor 14 d following implantation of U251 cells.Magnetic resonance imaging(MRI)was used to in vivo track the migration of EPCs in the tumor.The expression of gene products was determined by in vivo Tc-99m single photon emission computed tomography(SPECT).The findings were validated with immunohistochemistry(IHC).RESULTS:EPCs were successfully transfected with the adenoviral vectors carrying hNIS which was proved by significantly(P<0.05)higher uptake of Tc-99m in transfected cells.Viability of EPCs following transfection and iron labeling was not altered.In vivo imaging showed the presence of iron positive cells and the expression of transgene(hNIS)product on MRI and SPECT,respectively,all over the tumors following administration of transfected and iron labeled EPCs in the tumors.IHC confirmed the distribution of EPC around the tumor away from the injection site and also showed transgene expression in the tumor.The results indicated the EPCs’ability to deliver adenoviral vectors into the glioma upon intratumor injection.CONCLUSION:EPCs can be used as vehicle to deliver adenoviral vector to glioma and also act as imaging probe at the same time.Nadimpalli Ravi S Varma Kenneth N Barton Branislava Janic Adarsh Shankar ASM Iskander Meser M Ali Ali S Arbab 2013World Journal of Clinical Oncology2013,4,4:0
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