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| 1 | Assessment of vascular invasion in gastric cancer: A comparative study显示文摘AIM: To evaluate and compare detection of lymphatic and blood vessel invasion (LVI and BVI) by hematox-ylin-eosin (HE) and immunohistochemistry (IHC) in gastric cancer specimens, and to correlate with lymph node status. METHODS: IHC using D2-40 (a lymphatic endothelial marker) and CD34 (a pan-endothelial marker) was performed to study LVI and BVI in surgical specimens froma consecutive series of 95 primary gastric cancer cases. The results of the IHC study were compared with the detection by HE using McNemar test and kappa index. The morphologic features of the tumors and the presence of LVI and BVI were related to the presence of lymph node metastasis. A χ2 test was performed to obtain associations between LVI and BVI and other prognostic factors for gastric cancer. RESULTS: The detection rate of LVI was considerably higher than that of BVI. The IHC study identified eight false-positive cases and 13 false-negative cases for LVI, and 24 false-positive cases and 10 false-negative cases for BVI. The average Kappa value determined was moderate for LVI (k=0.50) and low for BVI (k=0.20). Both LVI and BVI were statistically associated with the presence of lymph node metastasis (HE: P=0.001, P=0.013, and IHC: P=0.001, P=0.019). The mor-phologic features associated with LVI were location of the tumor in the distal third of the stomach (P=0.039), Borrmann's macroscopic type (P=0.001), organ inva-sion (P=0.03) and the depth of tumor invasion (P=0.001). The presence of BVI was related only to the depth of tumor invasion (P=0.003). CONCLUSION: The immunohistochemical identification of lymphatic and blood vessels is useful for increasing the accuracy of the diagnosis of vessel invasion and for predicting lymph node metastasis. | Letícia Trivellato Gresta Ismael Alves Rodrigues-Júnior Lúcia Porto Fonseca de Castro Geovanni Dantas Cassali Mnica Maria Demas lva-res Cabral | 2013 | World Journal of Gastroenterology2013，19，24： | 8 |
| 2 | Endoscopic management of Dieulafoy's lesion using Isoamyl-2-cyanoacrylate显示文摘Dieulafoy's lesion (DL) is a rare but important cause of obscure gastrointestinal bleeding that may be over-looked during diagnostic endoscopy. Mortality rates are similar to those of other causes for gastrointestinal bleeding. Diagnosis by upper endoscopy is the modal-ity of choice during acute bleeding. In the absence of active bleeding, the lesion resembles a raised nipple or visible vessel. There are no guidelines regarding effective selective therapy for DL, when diagnosed, en-doscopist experience is the major determinant of the treatment strategy. Following our strategy, an expert endoscopist with a skilled assistant should have a high rate of successful DL diagnosis when an obscured gas-trointestinal lesion is suspected. Cyanoacryltes com-pounds have been used successfully in management of Gastric varices and DLs. To our knowledge, there have been no previous reports regarding use of isoamyl-2-cyanoacrylate (AMCRYLATE ; Concord Drugs Ltd.,Hyderabad, India) as an effective therapy for gastric DL without serious complications. In our case study, Isoamyl-2-cyanoacrylate (AMCRYLATE) was effective and safe for treating DL. Surgical wedge resection of the lesion should be considered as a therapeutic option if endoscopic therapy fails. | Abd Elrazek M Aly Abd Elrazek Nakamura Yoko Moriguchi Hiroki Mohamed Afify Mohamed Asar Badr Ismael Magdy Salah | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，8： | 3 |
| 3 | Iron recovery from sulphate leach liquors in zinc hydrometallurgy 显示文摘 | ISMAEL M R C CARVALHO J M R | 2003 | Minerals Engineering2003，16，： | 1 |
| 4 | Recovery of phenol from aqueous solutions using liquid membranes with cyanex 923显示文摘 | Reis M T A De freitas O M Ismael M R C | 2007 | J Membrane Sci2007，305，1： | 1 |
| 5 | Transition metal complexes with 8-hydroxyquinoline and Kelex 100 in micellar system:stoichiometry of the complexes and kinetics of dissociation in acid media显示文摘 | ISMAEL M TONDRE C | 1994 | Separate Science Technology1994，29，： | 1 |
| 6 | Adsorption of dyes from aqueous solutions by microwave modified bamboo charcoal显示文摘 | LIAO P ISMAEL Z M ZHANG W | 2012 | Chem Eng J2012，195，339： | 1 |
| 7 | Differential effects ofvegetation restoration in Mediterranean abandoned crop-land by secondary succession and pine plantations on birdassemblages显示文摘 | Rey B Jose M Ismael G | 2010 | Forest Tcology and Managenent2010，260，1： | 1 |
| 8 | Non-digestible oligosaccharides: A review 显示文摘 | SOLANGE I M ISMAEL M M | 2007 | Carbohydrate Polymers2007，68，： | 1 |
| 9 | Selective chemical oxidation or reduction of chlorophenols with potassium nitro-sodisulfonate显示文摘 | Elisa L Ismael C Edgar M | 2003 | Organic Chemistry in Mexico2003，7，： | 1 |
| 10 | Recovery of phenol from aqueous solutions using liquid membranes with Cyanex 923 显示文摘 | Reis M T A Freitas O M F Ismael M R C | 2007 | Journal of Membrane Science2007，305，12： | 1 |
| 11 | Ferric sulphate/chloride leaching of zinc and minor elements from a sphalerite concentrate显示文摘 | SANTOS S M C MACHADO R M CORREIA M J N REIS M T A ISMAEL M R C CARVALHO J M R | 2010 | Minerals Engineering2010，23，8： | 1 |
| 12 | Ground-penetrat ing radar= a tool for monitoring bridge scour显示文摘 | Anderson N L Ismael A M Thitimakorn T | 2007 | ENVIRON MENTAL g> ENGINEERING GEOSCIENCE2007，13，1： | 1 |
| 13 | Mesoporous aluminosilica mon- oliths for the adsorptive removal of small organic pollutants显示文摘 | EI-Safty S A Shahat A Ismael M | 2012 | Journal of Hazardous Materials2012，02，： | 1 |
| 14 | Mic1-3knockoutof Toxoplasma gondii is a successful vaccine against chronic andcongenital toxoplasmosis in mice显示文摘 | Ismael A B Dimier-Poisson I Lebrun M | 2006 | J Infect Dis2006，194，8： | 1 |
| 15 | Effects of metoclopramide on gastric motility measured by short-term bio-impedance显示文摘AIM:To analyze the accuracy of short-term bio-impedance as a means of measuring gastric motility.METHODS: We evaluated differences in the short-term electrical bio-impedance signal from the gastric region in the following conditions: (1) fasting state, (2) after the administration of metoclopramide (a drug that induces an increase in gastric motility) and (3) after food ingestion in 23 healthy volunteers. We record-ed the real component of the electrical impedance signal from the gastric region for 1000 s. We performed a Fast Fourier Transform (FFT) on this data and then compared the signal among the fasting, medicated, and postprandial conditions using the median of the area under the curve, the relative area under the curve and the main peak activity.RESULTS: The median of the area under the curve of the frequency range in the region between 2-8 cycles per minute (cpm) decreased from 4.7 cpm in the fasting condition to 4.0 cpm in the medicated state (t=3.32, P=0.004). This concurred with the decrease seen in the relative area under the FFT curve in the region from 4 to 8 cpm from 38.3% to 26.6% (t=2.81, P=0.012) and the increase in area in the region from 2 to 4 cpm from 22.4% to 27.7%, respectively (t=-2.5, P=0.022). Finally the main peak position also decreased in the region from 2 to 8 cpm. Main peak activity in the fasting state was 4.72 cpm and declined to 3.45 cpm in the medicated state (t=2.47, P=0.025). There was a decrease from the fasting state to the postprandial state at 3.02 cpm (t=4.0, P=0.0013). CONCLUSION: Short-term electrical bio-impedance can assess gastric motility changes in individuals experiencing gastric stress by analyzing the area medians and relative areas under the FFT curve. | María-Raquel Huerta-Franco Miguel Vargas-Luna Kathleen M Capaccione Etna Yaez-Roldán Ulises Hernández-Ledezma Ismael Morales-Mata Teodoro Córdova-Fraga | 2009 | World Journal of Gastroenterology2009，15，38： | 1 |
| 16 | From upfront ne- phrectomy to preoperative chemotherapy and hack: a single institution experience in the treatment of Wilms tumor显示文摘 | Sultan I Masarweh M Ismael T | 2009 | J Pediatr Hematol Oncol2009，31，5： | 1 |
| 17 | Thermal reshaping of gold nanorods in micelles显示文摘 | Mohamed M B Ismael K Z Link S | 1998 | Journal of Physical Chemistry B1998，102，47： | 1 |
| 18 | Workability andsetting parameters evaluation of colloidal silica bonded refractorysuspensions显示文摘 | dos Anjos R D Ismael M R de Oliveira I R ei al | 2008 | Ceram Int2008，34，1： | 1 |
| 19 | Propriedades ter-mo-mecanicas de concretos refratdrios ligados por silica colloidal显示文摘 | Ismael M R Valenzuela F A 0 Polito L Af | 2007 | Ceramica2007，53，327： | 1 |
| 20 | Ecological indices as a tool for assessing pollution in E1-Dekhaila Harbour (Alexandria, Egypt) 显示文摘 | Ismael A A Dorgham M M | 2003 | Oceanologia2003，45，1： | 1 |
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