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| 1 | 尿钠排泄、血压、心血管病与死亡率的关系:社区前瞻性流行病学队列研究显示文摘WHO建议人群钠摄人<2 g/d作为预防心血管病的措施之一,但这一目标在任何国家都没有实现。该建议主要基于短期血压试验的个体水平数据,没有来自随机试验或观察性研究的关于低钠摄入与降低心血管事件的数据。前瞻性城市农村流行病学研究目前正在21个国家进行。该文对其中18个国家的数据进行分析,其中包含了临床结果数据。 | Mente A O'Donnell M Rangarajan S McQueen M Dagenais G Wielgosz A Lear S Ah STL Wei L Diaz R Avezum A Lopez-Jaramillo P Lanas F Mony P Szuba A Iqbal R Yusuf R Mohammadifard N Khatib R Yusoff K Ismail N Gulec S Rosengren A Yusufali A Kruger L Tsolekile LP Chifamba J Dans A Alhabib KF Yeates K Teo K Yusuf S 刘莉 叶鹏 | 2018 | 中华高血压杂志2018，26，12： | 29 |
| 2 | Detection of class 1 integron in Acinetobacter baumannii isolates collected from nine hospitals in Turkey显示文摘Objective:To investigate the antibiotic resistance genes inserted into class I and class 2integrons in Acinetobacler baumannii[A.baumannii)isolates obtained from nine different cities in Turkey.Methods:A collection of 281 A.baumannii clinical isolates were collected from nine diferenl state hospitals in Turkey and were confirmed as A.baumannU by conventional biochemical,API testing and bla_(-OXA-51)specific PCR.The isolates were examined by PCR for existence of class I and2 integron gene cassettes.Results:They were characterized by antimicrobial susceptibility testing and the highest resistance rates were determined for piperacillin(90.03%),ciprofloxacin(87.54%),cefepime and trimethoprim/sulfamethoxazole(81.13%).The lowest resistance rates was for cefotaxime(3.55%).class 1 integrons were detected in 6.4%(18/281)of A.baumannii strains and no class 2 integron was detected.The gene casselles of class 1 inlegrons AacCI-AAC(3)l-aadAI,AacCI-aadA1,AAC(3)-I,AAC(3)-I-AAC(3)-I-aadA1,TEM-1.AAC(3)-I-aadA1-AAC(3)-I-AAC(3)-I,AAC(3)-I-AAC(3)-I-AAC(3)-I-aadA1,AAC(3)-I-aadA1,AAC(3)-I-AAC(3)-I,AAC(3)-I-aadA1-AAC(3)-I-aadA1,AAC(3)-I-AAC(3)-I-aadA1-AAC(3)-I-aadA1 were detected in eighteen strains.The aac genes family were most frequently found integrated into the class 1 inlegrons and it was followed by aadA genes and TEM-1 genes.Conclusions:This is an extensive study on the distribulion of class 1 integron among A.baumannii in Turkey.In addition to these,two new alleles were observed.Their percentage rates of similarity to other cassettes are 95%aadA1(TK A18)and 89%,aadA 1(ANKA3). | Aysegül Copur Cicek Azer Ozad Düzgün Aysegül Saral Tuba Kayman Zeynep Cizmeci Pervin Ozlem Balci Tuba Dal Mehmet Firat Ismail Tosun Yasemin Ay Alitntop Ahmet Caliskan Yelda Yazici Cemal Sandalli | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，9： | 3 |
| 3 | Delaying surgery after neoadjuvant chemoradiotherapy improves prognosis of rectal cancer显示文摘AIM To investigate the prognostic effect of a delayed interval between neoadjuvant chemoradiotherapy(CRT) and surgery in locally advanced rectal cancer.METHODS We evaluated 87 patients with locally advanced mid-or distal rectal cancer undergoing total mesorectal excision following an interval period after neoadjuvant CRT at ?i?li Hamidiye Etfal Training and Research Hospital,Istanbul between January 2009 and January 2014.Patients were divided into two groups according to the intervalbefore surgery: < 8 wk(group Ⅰ) and ≥ 8 wk(group Ⅱ).Data related to patients,cancer characteristics and pathological examination were collected and analyzed.RESULTS When the distribution of timing between group Ⅰ(n = 45) and group Ⅱ(n = 42) was viewed,comparison of interval periods(median ± SD) of groups showed a significant difference of as 5 ± 1.28 wk in group Ⅰ and 10.1 ± 2.2 wk in group Ⅱ(P < 0.001).The median follow-up period for all patients was 34.5(9.9-81) mo.group Ⅱ had significantly higher rates of pathological complete response(p CR) than group Ⅰ had(19% vs 8.9%,P = 0.002).Rate of tumor regression grade(TRG) poor response was 44.4% in group Ⅰ and 9.5% in group Ⅱ(P < 0.002).A poor pathological response was associated with worse disease-free survival(P = 0.009).The interval time did not show any association with local recurrence(P = 0.79).CONCLUSION Delaying the neoadjuvant CRT-surgery interval may provide nodal down-staging,improve p CR rate,and decrease the rate of TRG poor response. | Mehmet Mihmanli Esin Kabul Gürbulak Ismail Ethem Akgün Mustafa Fevzi Celayir Pinar Yazici Deniz Tuncel Tuba Tülin Bek Ayhan Oz Sinan Omeroglu | 2016 | World Journal of Gastrointestinal Oncology2016，8，9： | 3 |
| 4 | Review of interfer- ence avoidance schemes in femtocell networks 显示文摘 | ISMAIL S NG C K NOORDIN N K | 2011 | Scientific Re- search and Essays2011，6，15： | 1 |
| 5 | Impact of a nurse-led clinic for chronic constipation in children显示文摘 | Ismail N Ratchford I Proudfoot C | | 0，，： | 1 |
| 6 | The effect of chitosan load- ing on the curing characteristics, mechanical and morphologi- cal properties of chitosan-filled natural rubber(NR) , epoxi- dised natural rubber (ENR) and styrene-butadiene rubber (SBR) compounds 显示文摘 | Ismail H Shaari S M Othman N | 2011 | Polymer Testing2011，30，7： | 1 |
| 7 | Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections 显示文摘 | Mattner J Debord KL Ismail N | 2005 | Nature2005，434，7032： | 1 |
| 8 | Tool path planning for five-axis machining using the principal axis method显示文摘 | RAO N ISMAIL F BEDI S | 1997 | International Journal of Machine Tools and Manufacture1997，37，7： | 1 |
| 9 | Renal replacement therapies in the elderly part in renal transplantation显示文摘 | ISMAIL N HAKIM R M HELDERMAN J H | 1994 | Am J Kidney Dis1994，23，： | 1 |
| 10 | Macrophage microvesicles induce macrophage differentiation and miR 223 transfer 显示文摘 | Ismail N Wang Y Dakhlallah D | 2013 | Blood2013，121，6： | 1 |
| 11 | Instructional strategy in the teaching of computer programming:a need assessment analyses显示文摘 | Ismail M N Ngah N A Umar I N | 2010 | The Turkish Online Journal of Educational Technology2010，9，2： | 1 |
| 12 | Surgical management of hemodi alysis-related central venous occlusive disease:atreatment algorithm显示文摘 | Anaya-Ayala JE Bellows PH Ismail N | 2011 | Ann Vasc Surg2011，25，1： | 1 |
| 13 | Surgical management of hemodialysis-related central venous oc-clusive disease: a treatment algorithm显示文摘 | Anaya-Ayala JE Bellows PH Ismail N | 2011 | Ann Vase Surg2011，25，1： | 1 |
| 14 | Rapid and sensitive assay method for simultaneous quantification of urinary nicotine and cotinine using gas chromatography-mass spectrometry显示文摘 | MAN C N GAM L H ISMAIL S | 2006 | Journal of Chromatography B2006，844，： | 1 |
| 15 | Cholangiocarcinoma in patients with primary sclerosing cholangitis:a multicenter case-control study显示文摘 | Chalasani N Baluyut A Ismail A | 2000 | Hepatology2000，31，1： | 1 |
| 16 | Comparison of minimum bias and maximum likelihood method for claim severity 显示文摘 | Ismail N Jemain A A | 2009 | CAS Forum2009，2009，： | 1 |
| 17 | A recent progress in thin film composite membrane:a review显示文摘 | Lau W J Ismail A F Misdan N | 2012 | Desalination2012，287，： | 1 |
| 18 | A review of the effects of emerging contaminants in wastewater and options for their removal显示文摘 | Bolong N Ismail A Salim M R | 2009 | Desalination2009，239，1： | 1 |
| 19 | Shear Strength Characteristics of Sand-Waste Material Mixture显示文摘 | Chow S H Ismail N Ghani A | 2009 | The Institution of Engineers2009，70，1： | 1 |
| 20 | Eff-ect of dexmedetomidine premedication on the intraocular pressure changes after succinylcholine and intubation显示文摘 | MOWAFI H A ALDOSSARY N ISMAIL S A | 2008 | Br J Anaesth2008，100，4： | 1 |
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