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| 1 | Chronic hepatitis B infection in pregnancy显示文摘There are no standard guidelines to follow when a patient with chronic hepatitis B infection becomes pregnant or desires pregnancy. Topics to consider include which patients to treat, when to start treatment, what treatment to use and when to stop treatment. Without any prophylaxis or antiviral therapy, a hepatitis B surface antigen and E antigen positive mother has up to a 90% likelihood of vertical transmission of hepatitis B virus(HBV) to child. Standard of care in the United States to prevent perinatal transmission consists of administration of hepatitis B immune globulin and HBV vaccination to the infant. The two strongest risk factors of mother to child transmission(MTCT) of HBV infection despite immunoprophylaxis are high maternal HBV viral load and high activity of viral replication. The goal is to prevent transmission of HBV at birth by decreasing viral load and/or decreasing activity of the virus. Although it is still somewhat controversial, most evidence shows that starting antivirals in the third trimester is effective in decreasing MTCT without affecting fetal development. There is a growing body of literature supporting the safety and efficacy of antiviral therapies to reduce MTCT of hepatitis B. There are no formal recommendations regarding which agent to choose. Tenofovir, lamivudine and telbivudine have all been proven efficacious in decreasing viral load at birth without known birth defects, but final decision of which antiviral medication to use will have to be determined by physician and patient. The antivirals may be discontinued immediately if patient is breastfeeding, or within first four weeks if infant is being formula fed. | Jennifer R Lamberth Sheila C Reddy Jen-Jung Pan Kevin J Dasher | 2015 | World Journal of Hepatology2015，7，9： | 32 |
| 2 | 烟酰胺磷酸核糖基转移酶促进肺血管重塑,是肺动脉高压的治疗靶点显示文摘肺动脉高压(pulmonary arterial hypertension,PAH)是一种严重的进行性疾病,其标志之一是肺血管重塑。烟酰胺磷酸核糖基转移酶(nicotinamide phosphoribosyl transferase,NAMPT)是调节细胞内烟酰胺腺嘌呤二核苷酸水平、细胞氧化还原状态,调节组蛋白脱乙酰酶,促进细胞增殖和抑制凋亡的一种细胞酶。研究人员假设NAMPT可促进肺血管重塑, | Chen J Sysol JR Singla S Zhao S Yamamura A Valdez-Jasso D Abbasi T Shioura KM Sahni S Reddy V Sridhar A Gao H Torres J Camp SM Tang H Ye SQ Comhair S Dweik R Hassoun P Yuan JX Garcia JG Machado RF 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，2： | 10 |
| 3 | Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection显示文摘 | Arie Regev Mariana Berho Lennox J Jeffers Clara Milikowski Enrique G Molina Nikolaos T Pyrsopoulos Zheng-Zhou Feng K.Rajender Reddy Eugene R Schiff | 2002 | The American Journal of Gastroenterology2002，，10： | 7 |
| 4 | Cytokinin signaling regulates pavement cell morphogenesis in Arabidopsis显示文摘难题有交错的脑叶的塑造片的 Arabidopsis 叶人行道房间(PC ) 并且缩排是一个好模型系统调查在纸巾以内协调房间极性和形状形成的机制。植物生长素被显示了 GTPase 依赖的发信号由激活 ROP 协调 interdigitation 小径。识别另外的部件或机制,我们与反常 PC 形态发生为异种屏蔽了并且发现细胞激动素发信号调整 PC interdigitation 模式。在细胞激动素累积的减小和在细胞激动素发信号的缺点(例如在 ARR7-over-expressing 线, ahk3cre1 细胞激动素受体异种,和 ahp12345 细胞激动素表明异种) 提高的 PC interdigitation,而细胞激动素的生产过剩和细胞激动素在一根 ARR20 在表示上线发信号的在激活上在整个子叶推迟了或废除 PC interdigitation。基因、生物化学的分析建议表明 ROP 在上游的行为压制交错的模式的形成的那细胞激动素。我们的结果提供控制 PC 形状的小径的新奇机械学的理解并且揭开为细胞激动素在房间形态发生发信号的一个新角色。 | Hongjiang Li Tongda Xu Deshu Lin Mingzhang Wen M ingtang Xie Jērōme Duclercq Agnieszka Bielach Jungmook Kim G Venugopala Reddy Jianru Zuo Eva Benková Jiгi Friml Hongwei Guoz Zhenbiao Yang | 2013 | Cell Research2013，23，2： | 2 |
| 5 | Functional analysis ofthe domain structure of tumor necrosis factor-alpha converting enzyme显示文摘 | Reddy P Slack J L Davis R | | 0，，： | 2 |
| 6 | Bearing capacity of footings on anisotropic soils显示文摘 | REDDY A S SRINICASAN R J | 1970 | Journal of the Soil Mechanics and Foundations Division ASCE1970，96，6： | 1 |
| 7 | Fast RCS Computation over a Frequency Band Using Method of Moments in Conjunction with Asymptotic Waveform Evaluation Technique显示文摘 | Reddy C J Deshpande M D Cockrell C R | 1998 | IEEE Trans on Antennas and Propagation1998，46，8： | 1 |
| 8 | Optimal operating Schedule of Irrigation Distribution system 显示文摘 | SURYAVANSHI A R REDDY J M | 1986 | Agricultural Water Management1986，11，： | 1 |
| 9 | Solvent extraction of Hf(IV) from acidic chloride solutions using Cyanex 302显示文摘 | REDDY B R KUMAR J R RAJA K P REDDY A V | 2004 | Minerals Engineering2004，17，： | 1 |
| 10 | Efficacy and safety of low dose desmopressin orally disintegra- ti'ng tablet in women with nocturia: Results of a multi- center, randomized, double-blind, placebo controlled, parallel group study显示文摘 | Sand P K Dmoehowski R R Reddy J | 2013 | J Urol2013，190，3： | 1 |
| 11 | Nitrite Inhibition of Clostridum botulinum : Electron Spin Resonance Detection of Iron - nitric Oxide Complexes 显示文摘 | REDDY D LANCASTER J R CORNFORTH D P | 1983 | Science1983，221，： | 1 |
| 12 | The coagulopathy of acute liver failure and implications for intracranial pressure monitoring 显示文摘 | Munoz S J Reddy R Lee W | 2008 | Neurocrit Care2008，9，1： | 1 |
| 13 | Interaction and spatial distribution of wetland nitrogen processes 显示文摘 | Martin J F Reddy K R | 1997 | Ecol Model1997，105，1： | 1 |
| 14 | Vitamin K deficiency developing in patients with renal failure treated with cephalosporin antibiotics 显示文摘 | REDDY J BAILEY R R | 1980 | NZ MedJ1980，92，672： | 1 |
| 15 | Inhibition by dietary menhaden oil of cyclooxygenase-1 and -2 in N-nitrosomethylurea-induced rat mammary tumors显示文摘 | Singh J Reddy BS | 1999 | Int J Oncol1999，14，3： | 1 |
| 16 | Effect of feeding complete feeds on various nitrogen fraction and total VFA concentration in the rumen fluid of sheep显示文摘 | REDDY K J REDDY M R | 1985 | India J Anim Sci1985，55，9： | 1 |
| 17 | Nitrification denitrification at the plant root sediment interfaces in wetlands显示文摘 | REDDY K R PATRICH J W H LINDAU C W | 1998 | Limnology and Oceanography1998，34，6： | 1 |
| 18 | Surface acidity study of Mn ^+-montmorillonite clay catalysts by FT-IR spectroscopy: Correlation with esterification activity 显示文摘 | Reddy C R Nagendrappa G Prakash B S J | 2007 | Catal Commun2007，8，： | 1 |
| 19 | Synthesis and biological evaluation of EC140:a no- vel folate-targeted vinca alkaloid conjugate 显示文摘 | LEAMON C P REDDY J A VLAHOV I R | 2006 | Bio- conjug Chem2006，17，5： | 1 |
| 20 | Phosphorus sorbing materials : sorption dynamics and physicochemical characteristics 显示文摘 | Leader J W Dunne E J Reddy K R | 2008 | Journal of Environment Quality2008，37，1： | 1 |
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