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| 1 | 查看详情显示文摘 | Shin J.H Jung S.S Kim K.W Ahn H.J Ahn J.H.J | | 0，，： | 1 |
| 2 | A decision support system for the prediction of microbial food safety and food quality显示文摘 | T Wijtzes K van’t Riet J.H.J Huis in’t Veld M.H Zwietering | 1998 | International Journal of Food Microbiology1998，，1： | 1 |
| 3 | Appetite of an epiphyte:Quantitative monitoring of bacterial sugar consumption in the phyllosphere显示文摘 | Leveau J.H.J Lindow S.E | | 0，，： | 1 |
| 4 | Phyllosphere microbiology显示文摘 | Lindow S.E Leveau J.H.J | | 0，，： | 1 |
| 5 | Silencing of unpaired chromatin and histone H2A ubiquitination in mammalian meiosis显示文摘 | Baarends W.M Wassenaar E Van Der Laan R Hoogerbrugge J Sleddens-Linkels E Hoeijmakets J.H.J De Boer P Grootegoed J.A | | 0，，3： | 1 |
| 6 | Effect of water-saving irrigation on rice yield and water use in typical lowland conditions in Asia显示文摘 | P Belder B.A.M Bouman R Cabangon Lu Guoan E.J.P Quilang Li Yuanhua J.H.J Spiertz T.P Tuong | 2003 | Agricultural Water Management2003，，3： | 1 |
| 7 | Effect of water-saving irrigation on rice yield and water use in typical lowland conditions in Asia显示文摘 | P Belder B.A.M Bouman R Cabangon Lu Guoan E.J.P Quilang Li Yuanhua J.H.J Spiertz T.P Tuong | 2003 | Agricultural Water Management2003，，3： | 1 |
| 8 | 散发上运动神经元综合征成年患者的spastin基因突变显示文摘Mutation of the spastin gene is the single most common cause of pure hereditary spastic paraparesis. In patients with an unexplained sporadic upper motor neuron (UMN) syndrome, clinical distinction between primary lateral sclerosis and sporadic hereditary spastic paraparesis may be problematic. To investigate whether spastin mutations are present in patients with primary lateral sclerosis and sporadic hereditary spastic paraparesis, we screened the spastin gene in 99 Dutch patients with an unexplained, apparently sporadic, adult-onset UMN syndrome. We found 6 mutations, of which 4 were novel, in the subgroup of 47 patients with UMN symptoms restricted to the legs (13% ). Another novel spastin mutation was found in a patient with a rapidly progressive spinal and bulbar UMN syndrome that progressed to amyotrophic lateral sclerosis. In the patients with arm or bulbar UMN symptoms and slow progression, no spastin mutations were found. Our study shows that spastin mutations are a frequent cause of apparently sporadic spastic paraparesis but not of primary lateral sclerosis. | Brugman F Wokke J.H.J Scheffer H. 江山 | 2006 | 世界核心医学期刊文摘(神经病学分册)2006，2，5： | 0 |
| 9 | 双侧丘脑底核刺激对帕金森病患者平衡和手指控制能力的影响显示文摘We aimed to quantify the effects of bilateral subthalamic nucleus (STN) stimulation in Parkinson’s disease (PD) on stance and gait (“ axial' motor control), and related this to effects on finger movements (“ appendicular' motor control). Fourteen PD patients and 20 matched controls participated. Subjects completed several balance and gait tasks (standing with eyes open or closed, on a normal or foam surface; retropulsion test; walking with eyes closed; walking up and down stairs; Get Up and Go test). Postural control was quantified using trunk sway measurements (angle and angular velocity) in the roll and pitch directions. Subjects further performed a pinch grip reaction time task, where we measured isometric grip forces, as well as movement and reaction times. Patients were examined with STN stimulators switched on or off (order randomised across patients), always after a supramaximal levodopa dosage. STN stimulation improved postural control, as reflected by a reduced trunk sway tremor during stance, a reduced duration for all gait tasks, an increased trunk pitch velocity while rising from a chair, and improved roll stability. STN stimulation also improved finger control, as reflected by a reduced time to reach maximum grip force, without altering reaction times and maximum force levels. Improvements in finger control timing did not correlate with reduced task durations during gait. We conclude that STN stimulation affords improvement of postural control in PD, over and above optimal drug treatment. STN stimulation also provides a simultaneous effect on distal and axial motor control. Because improvements in distal and axial motor control were not correlated, we assume that these effects are mediated by stimulation of different structures within the STN. | Vrancken A.M.P.M Allum J.H.J Peller M. B.R. Bloem 刘凯 | 2006 | 世界核心医学期刊文摘(神经病学分册)2006，2，5： | 0 |
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