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| 1 | Seminal biomarkers for the evaluation of male infertility显示文摘为努力与他们的搭挡一起怀孕的男人,诊断工具被限制并且经常由仅仅标准精液分析组成。这基线测试用作男富饶的一个粗略的评价,离开需要另外的诊断 biomarkers 的病人和临床医生。精液从因此,这评论在某些男不孕情形在当前、新奇的精液的 biomarkers 上集中包括自然富饶,区分精子缺乏病原学,并且预言的繁殖的腺帮助了的男性包含分子的最高的集中繁殖技术成功。当前可得到的测试包括 antisperm 抗体试金, DNA 破碎索引,在 situ 杂交的精子荧光,和另外的历史的精子功能的测试。当前的试金的差的诊断能力导致了继续的努力发现更预兆的 biomarkers。genomics, epigenetics, proteomics, transcriptomics,和为新奇男不孕 biomarkers 的发展的 metabolomics 抓住诺言的地里的新兴的研究。TEX101, ECM1,和 ACRV1 的精液的基于蛋白质的试金已经是可得到的或在为临床的使用的最后的开发中。当我们试图理解男不孕的 pathophysiologic 过程, DNA, RNA,蛋白质,或代谢物的另外的面板正在被探索。未来冒险将需要继续数据集成和确认让临床上有用的不孕 biomarkers 的开发帮助男不孕诊断,处理,并且建议。 | Jared M Bieniek Andrei P Drabovich Kirk C Lo | 2016 | Asian Journal of Andrology2016,18,3: | 15 |
| 2 | Platelet-rich plasma for muscle injuries: A systematic review of the basic science literature显示文摘BACKGROUND Platelet-rich plasma(PRP) is an increasingly used biologic adjunct for muscle injuries, as it is thought to expedite healing. Despite its widespread use, little is known regarding the mechanisms by which PRP produces its efficacious effects in some patients.AIM To clarify the effects of PRP on muscular pathologies at the cellular and tissue levels by evaluating the basic science literature.METHODS A systematic review of PubMed/MEDLINE and EMBASE databases was performed using the Preferred Reporting Items for Systematic Reviews and MetaAnalyses(PRISMA) guidelines and checklist. Level III in vivo and in vitro studies examining PRP effects on muscles, myocytes and/or myoblasts were eligible for inclusion. Extracted data included PRP preparation methods and study results.RESULTS Twenty-three studies were included(15 in vivo, 6 in vitro, 2 in vitro/in vivo). Only one reported a complete PRP cytology(platelets, and red and white blood cell counts). Five in vitro studies reported increased cellular proliferation, four reported increased gene expression, and three reported increased cellular differentiation. Five in vivo studies reported increased gene expression, three reported superior muscle regeneration, and seven reported improved histological quality of muscular tissue.CONCLUSION The basic science literature on the use of PRP in muscle pathology demonstrates that PRP treatment confers several potentially beneficial effects on healing in comparison to controls. Future research is needed to determine optimal cytology,dosing, timing, and delivery methods of PRP for muscle pathologies. | Kyle N Kunze Charles P Hannon Jared D Fialkoff Rachel M Frank Brian J Cole | 2019 | World Journal of Orthopedics2019,10,7: | 6 |
| 3 | DNA microarray applications in functional genomics显示文摘 | Jares P | 2006 | Ultrastruct Pathol2006,30,: | 1 |
| 4 | Vitamin D Status and Cardiovascular Health : a 2009 update 显示文摘 | Erin D Michos Jared P Reis Michal L Melamed | 2010 | The Open Clinical Chemistry Journal2010,3,: | 1 |
| 5 | Preclinical and clinical evaluations of ABX-EGF, a fully human anti-epidermal growth factor receptor antibody显示文摘 | Kenneth A Foon Xiao-Dong Yang Louis M Weiner Arie S Belldegrun Robert A Figlin Jeffrey Crawford Eric K Rowinsky Janice P Dutcher Nicholas J Vogelzang Jared Gollub John A Thompson Garry Schwartz Ronald M Bukowski Lorin K Roskos Gisela M Schwab | 2004 | International Journal of Radiation Oncology Biology Physics2004,,3: | 1 |
| 6 | Advances in the understanding of mantle cell lymphoma 显示文摘 | Jares P Campo E | 2008 | Br J Haematol2008,142,2: | 1 |
| 7 | Serum vitamin D,parathyroid hormone levels,and carotid atherosclerosis显示文摘 | Jared P Reis Denise von Muhlen Erin D Michos | | 0,,207: | 1 |
| 8 | Serum vi- tamin D parathyroid hormone levels and carotid atherosclerosis 显示文摘 | Jared P Reis Denise Von Mtlhlen Erin D Michos | 2009 | Atheroselerosis2009,20,7: | 1 |
| 9 | Genetic and moleeular pathogenesis of mantle cell lymphoma: perspectives for new targeted therapeutics显示文摘 | Jares P Colomer D Campo E | 2007 | Nat Rev Caneer2007,7,10: | 1 |
| 10 | Gene expression profiling of acute myeloid leukemia wit h t ranslocation t ( 8 ; 16 ) (p11 ; p13 ) and MYST3- CREBBP rearrangement reveals a distinctive signature with a specific pattern of HOX gene expression显示文摘 | Camos M Esteve J Jares P | 2006 | Cancer Res2006,66,14: | 1 |
| 11 | PRAD-1/cyclinD1 gene amplification correlates with messenger RNA over-expression and tumor progression in human laryngeal carcinomas显示文摘 | Jares P Fernandez PL Campo E | 1994 | Cancer Res1994,54,: | 1 |
| 12 | Potential pathogenic mechanisms of periosontitis associated pregnancy complications 显示文摘 | Offenbacher S Jared H L O'Reilly P G | 1998 | Ann Periodontol1998,3,3: | 1 |
| 13 | PRAD-1/cyclinDl geneamplification correlates with messenger RNA over expression and tumorprogression in human laryngeal carinomas 显示文摘 | Jares P Fernandez P L Campo E | 1994 | Cancer Res1994,54,48: | 1 |
| 14 | Advances in the understanding of mantle cell lymphoma显示文摘 | Jares P Campo E | 2008 | Br J Haematol2008,142,2: | 1 |
| 15 | Genetic and molecular pathogene- sis of mantle cell lymphoma: perspectives for new targeted ther- apeutics 显示文摘 | Jares P Colomer D Campo E | 2007 | Nat Rev Cancer2007,7,10: | 1 |
| 16 | Frequent polymorphic changes but not mutations of TRAIL receptors DR4 and DR5 in mantle cell lymphoma and other B-cell lymphoid neoplasms 显示文摘 | Fernandez V Jares P Bea S | 2004 | Haematologica2004,89,11: | 1 |
| 17 | PRAD-1/cycleD1 gene amplification correlates with messenger RNA overpression and tumor progression in human laryngeal carcinomas显示文摘 | Fernanclez Pl Campo E | 1994 | Cancer Res1994,549,17: | 1 |
| 18 | Gene expression profiling of acute myeloid leukemia with translocation t (8: 16) (p11; p13) and MYST3 CREBBP rearrangement reveals a distinctive signature with a specific pattern of HOX gene expression 显示文摘 | Camos M Esteve J Jares P | 2006 | CancerRes2006,66,14: | 1 |
| 19 | Asymmetric pri- cing of implied systematic volatility in the cross-section of expected returns 显示文摘 | JARED D R JAMES S D DAVID R P | 2011 | Journal of Futures Markets2011,31,1: | 1 |
| 20 | Cyclin D1 and retinoblastoma gene expression in human breast carcinoma:correlation with tumor proliferation and oestrogen receptor status显示文摘 | Jares P Rey JM Fernandes PL | | 0,,01: | 1 |