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| 1 | Clarifying sub-genomic positions of QTLs for flowering habit and fruit quality in U.S. strawberry (Fragaria×ananassa) breeding populations using pedigree-based QTL analysis显示文摘The cultivated strawberry(Fragaria×ananassa)is consumed worldwide for its flavor and nutritional benefits.Genetic analysis of commercially important traits in strawberry are important for the development of breeding methods and tools for this species.Although several quantitative trait loci(QTL)have been previously detected for fruit quality and flowering traits using low-density genetic maps,clarity on the sub-genomic locations of these QTLs was missing.Recent discoveries in allo-octoploid strawberry genomics led to the development of the IStraw90 single-nucleotide polymorphism(SNP)array,enabling high-density genetic maps and finer resolution QTL analysis.In this study,breeder-specified traits were evaluated in the Eastern(Michigan)and Western(Oregon)United States for a common set of breeding populations during 2 years.Several QTLs were validated for soluble solids content(SSC),fruit weight(FWT),pH and titratable acidity(TA)using a pedigree-based QTL analysis approach.For fruit quality,a QTL for SSC on linkage group(LG)6A,a QTL for FWT on LG 2BII,a QTL for pH on LG 4CII and two QTLs for TA on LGs 2A and 5B were detected.In addition,a large-effect QTL for flowering was detected at the distal end of LG 4A,coinciding with the FaPFRU locus.Marker haplotype analysis in the FaPFRU region indicated that the homozygous recessive genotype was highly predictive of seasonal flowering.SNP probes in the FaPFRU region may help facilitate marker-assisted selection for this trait. | Sujeet Verma Jason D Zurn Natalia Salinas Megan M Mathey Beatrice Denoyes James F Hancock Chad E Finn Nahla V Bassil Vance M Whitaker | 2017 | Horticulture Research2017,4,1: | 10 |
| 2 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014,5,2: | 5 |
| 3 | Optimal struc- ture, market dynamism, and the strategy of simple rules显示文摘 | Jason P D Kathleen M E Bingham C B | 2009 | Administrative Science Quarterly2009,54,3: | 1 |
| 4 | Optima/ structure, market dynamism, and the strategy of simple rules 显示文摘 | JASON P D KATHLEEN M E CHRISTOPHER B B | 2009 | Administrative Science Quarterly2009,,9: | 1 |
| 5 | Use of solid-phase microextration to detect and quantify gas-phase dicarbonyls in indoor environments显示文摘 | Bruce D Pacolay Jason E Ham | 2006 | Journal of Chromatography A2006,1,3: | 1 |
| 6 | An atomic-level of melting using femtosecond electron diffraction显示文摘 | BRADLEY J S JASON R D ROBERT E J | 2003 | Science2003,302,21: | 1 |
| 7 | Serum resistin (FIZZ3) protein is increased in obese humans 显示文摘 | Mikako D Y Jason E | 2003 | J Clin Endocrinol Metab2003,88,11: | 1 |
| 8 | Use of solid-phase microextraction to detect and quantify gas-phase dicarbonyls in indoor environments显示文摘 | Jason E Ham Wells J R | 2006 | Journal of Chromatography A2006,1131,: | 1 |
| 9 | Toxic activity from cultures of Karlodinium micrum (Gyrodinium galatheanum ) (Dinophyceae)-a dinoflagellate associated with fish mortalities in an estuarine aquaculture facility显示文摘 | Jonathan R D Daniel E T Jason E A | 2002 | Harmful Algae2002,1,: | 1 |
| 10 | Rethinking in vitro embryoculture:new developments in culture platforms and potential to improve as-sisted reproductive technologies显示文摘 | SMITH G D TAKAYAMA S JASON E | 2012 | Biology of Reproduction2012,86,3: | 1 |
| 11 | An atomiclevel of melting using femtosecond electron diffraction显示文摘 | BRADLEY J S JASON R D ROBERT E J | 2003 | Science2003,302,21: | 1 |
| 12 | Serum resistin (FIZZ3) protein is increased in obese humans 显示文摘 | Mikako D Jason E Beth E | 2003 | J Clin Endocrinol Metab2003,88,: | 1 |
| 13 | Effect of optimal torque control on rotor loss of fault-tolerant permanent magnet brushless machines 显示文摘 | JASON D E KAIS A WANG J | 2002 | IEEE Transaction on Magnetic2002,38,5: | 1 |
| 14 | Acute respiratory distress syndrome 40 years later:time to revisit its definition显示文摘 | Jason Phua Thomas E Stewart Niall D Ferguson | 2008 | Crit Care Med2008,36,10: | 1 |
| 15 | Triple-Transgenic Model of Alzheimer’s Disease with Plaques and Tangles显示文摘 | Salvatore Oddo Antonella Caccamo Jason D Shepherd M.Paul Murphy Todd E Golde Rakez Kayed Raju Metherate Mark P Mattson Yama Akbari Frank M LaFerla | 2003 | Neuron2003,,3: | 1 |
| 16 | Alternative Conceptualizations of the Relationship Between Voluntary Turnover and Organizational Performance显示文摘 | Shaw Jason D Gupta Nina Delery John E | 2005 | Academy of Management Journal2005,48,1: | 1 |
| 17 | An organizational-level analysis of voluntary and involuntary turnover显示文摘 | JASON D Shaw JONE E Delery | 1998 | Academy of Management Journal1998,,41: | 1 |
| 18 | A power link study of wireless non-radiative power transfer systems using resonant shield loops显示文摘 | Thomas E M Heebl Jason D Pfeiffer C | 2012 | IEEE Transactions on Circuits and Systems I:Regular Papers2012,59,9: | 1 |
| 19 | Software architecture critics in the argo design environment显示文摘 | Jason E Robbins Redmiles D F | 1998 | Knowledge-based Systems1998,11,1: | 1 |
| 20 | A novel blueprint for ‘top down’ differentiation defines the cervical squamocolumnar junction during development, reproductive life, and neoplasia显示文摘 | Michael Herfs Sara O Vargas Yusuke Yamamoto Brooke E Howitt Marisa R Nucci Jason L Hornick Frank D Mckeon Wa Xian Christopher P Crum | 2013 | J. Pathol2013,,3: | 1 |