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| 1 | WJD 5^(th) Anniversary Special Issues(2): Type 2 diabetes Type 2 diabetes and cardiovascular disease: Have all risk factors the same strength?显示文摘Diabetes mellitus is a chronic condition that occurs when the body cannot produce enough or effectively use of insulin.Compared with individuals without diabetes,patients with type 2 diabetes mellitus have a considerably higher risk of cardiovascular morbidity and mortality,and are disproportionately affected by cardiovascular disease.Most of this excess risk is it associated with an augmented prevalence of well-known risk factors such as hypertension,dyslipidaemia and obesity in these patients.However the improved cardiovascular disease in type 2 diabetes mellitus patients can not be attributed solely to the higher prevalence of traditional risk factors.Therefore other non-traditional risk factors may be important in people with type 2 diabetes mellitus.Cardiovascular disease is increased in type 2 diabetes mellitus subjects due to a complex combination of various traditional and non-traditional risk factors that have an important role to play in the beginning and the evolution of atherosclerosis over its long natural history from endothelial function to clinical events.Many of these risk factors could be common history for both di-abetes mellitus and cardiovascular disease,reinforcing the postulate that both disorders come independently from'common soil'.The objective of this review is to highlight the weight of traditional and non-traditional risk factors for cardiovascular disease in the setting of type 2 diabetes mellitus and discuss their position in the pathogenesis of the excess cardiovascular disease mortality and morbidity in these patients. | Iciar Martín-Timón Cristina Sevillano-Collantes Amparo Segura-Galindo Francisco Javier del Caizo-Gómez | 2014 | World Journal of Diabetes2014,5,4: | 32 |
| 2 | Exploiting the diversity of tomato:the development of a phenotypically and genetically detailed germplasm collection显示文摘A collection of 163 accessions,including Solanum pimpinellifolium,Solanum lycopersicum var.cerasiforme and Solanum lycopersicum var.lycopersicum,was selected to represent the genetic and morphological variability of tomato at its centers of origin and domestication:Andean regions of Peru and Ecuador and Mesoamerica.The collection is enriched with S.lycopersicum var.cerasiforme from the Amazonian region that has not been analyzed previously nor used extensively.The collection has been morphologically characterized showing diversity for fruit,flower and vegetative traits.Their genomes were sequenced in the Varitome project and are publicly available(solgenomics.net/projects/varitome).The identified SNPs have been annotated with respect to their impact and a total number of 37,974 out of 19,364,146 SNPs have been described as high impact by the SnpEeff analysis.GWAS has shown associations for different traits,demonstrating the potential of this collection for this kind of analysis.We have not only identified known QTLs and genes,but also new regions associated with traits such as fruit color,number of flowers per inflorescence or inflorescence architecture.To speed up and facilitate the use of this information,F2 populations were constructed by crossing the whole collection with three different parents.This F2 collection is useful for testing SNPs identified by GWAs,selection sweeps or any other candidate gene.All data is available on Solanaceae Genomics Network and the accession and F2 seeds are freely available at COMAV and at TGRC genebanks.All these resources together make this collection a good candidate for genetic studies. | Estefanía Mata-Nicolás Javier Montero-Pau Esther Gimeno-Paez Víctor Garcia-Carpintero Peio Ziarsolo Naama Menda Lukas A.Mueller JoséBlanca Joaquín Cañizares Esther van der Knaap María JoséDíez | 2020 | Horticulture Research2020,7,1: | 2 |
| 3 | Quality of Life Among Stroke Survivors Evaluated 1 Year after Stroke显示文摘 | JAVIER CA JOSE AE JOSE LG | 2000 | Stroke(S0039-2499)2000,31,: | 1 |
| 4 | The relationship between sleep and epilepsy显示文摘 | Rodrigo R Juan CA Javier SP | 2008 | Neurologist2008,14,: | 1 |
| 5 | Quality of life among stroke survivors evaluated 1 year after stroke 显示文摘 | Javier CA | 2000 | Stroke2000,31,12: | 1 |
| 6 | The relationship between sleep and epilepsy显示文摘 | Rodrigo R Juan CA Javier SP | 2008 | Neurologist2008,14,: | 1 |
| 7 | Seroprevalence and national distribution of human toxoplasmosis in Mexico: analysis of the 2000 and 2006 National Health Surveys显示文摘 | Heriberto Caballero-Ortega Felipe Javier Uribe-Salas Carlos J. Conde-Glez Carlos Cedillo-Pelaez José Antonio Vargas-Villavicencio Héctor Luna-Pastén Irma Ca?edo-Solares Luz Belinda Ortiz-Alegría Dolores Correa | 2012 | Transactions of the Royal Society of Tropical Medicine and Hygiene2012,,11: | 1 |
| 8 | Quality of life among stroke survivors evaluated 1 year after stroke 显示文摘 | Javier CA Jose AE JoseE LG | 2000 | Stroke(S0039- 2499)2000,31,: | 1 |
| 9 | Quality of life among stroke survivors evaluated 1 year after stroke显示文摘 | Javier CA | 2000 | Stroke2000,31,12: | 1 |
| 10 | Quality of life among stroke survivors evaluated 1 year after stroke 显示文摘 | Javier CA Jose AE Jose LG | 2000 | Stroke2000,31,12: | 1 |
| 11 | Virgin olive oil reduces blood pressure in hypertensive elderly subjects显示文摘 | Javier S. Perona Julio Ca?izares Emilio Montero José M. Sánchez-Dom??nguez Angel Catalá Valentina Ruiz-Gutiérrez | 2004 | Clinical Nutrition2004,,5: | 1 |
| 12 | Enhanced regeneration of tomato and pepper seedling explants for Agrobacterium-mediated transformation显示文摘 | Javier Pozueta-Romero Guy Houlné Luis Ca?as Rodolphe Schantz Jesús Chamarro | 2001 | Plant Cell Tissue and Organ Culture2001,,2: | 1 |
| 13 | Quality of life among stroke survivors evaluated 1 year after stroke:experience of a stroke unit显示文摘 | Javier CA Jose AE Jose LG | | 0,,12: | 1 |
| 14 | The relationship between sleep and epilepsy显示文摘 | Rodrigo R Juan CA Javier SP | 2008 | The Neurologist2008,15,2: | 1 |
| 15 | The relationship between sleep and epilepsy显示文摘 | Rodrigo R Juan CA Javier SP | 2008 | The Neurologist2008,14,: | 1 |
| 16 | Quality of LifeAmong St roke Survivors Evaluated 1 Year after Stroke显示文摘 | Javier CA Jose AE Jose LG | 2000 | Stroke(S0039-2499)2000,31,: | 1 |
| 17 | Quality of life among stroke sur- vivors evaluated year after stroke 显示文摘 | Javier CA Jose AE Jose LG | 2000 | Stroke ( S0039-2499 )2000,31,5: | 1 |
| 18 | Quality of life among stroke survivors evaluated 1 year after stroke显示文摘 | Javier CA | | 0,,: | 1 |
| 19 | Exploring polysilicon deposition conditions through a laboratory CVD prototype显示文摘 | Alba Ramos Carlos del Ca?izo Javier Valdehita Juan Carlos Zamorano Araceli Rodríguez Antonio Luque | 2012 | Phys. Status Solidi C . 2012 (10‐)2012,,: | 1 |
| 20 | RAB7 Controls Melanoma Progression by Exploiting a Lineage-Specific Wiring of the Endolysosomal Pathway显示文摘 | Direna Alonso-Curbelo Erica Riveiro-Falkenbach Eva Pérez-Guijarro Metehan Cifdaloz Panagiotis Karras Lisa Osterloh Diego Megías Estela Ca?ón Tonantzin G. Calvo David Olmeda Gonzalo Gómez-López Osvaldo Gra?a Víctor Javier Sánchez-Arévalo Lobo David G. Pisa | 2014 | Cancer Cell2014,,: | 1 |