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| 1 | DRAGON-Lab―Next generation internet technology experiment platform显示文摘Testbed technology is very important in the development of the Internet. Similar to the present internet,next generation internet also starts from testbed. There are two kinds of testbeds,testbed networks like CNGI-CERNET2,Internet2,Geant;testbed systems like PlanetLab,NS2. DRAGON-Lab can be viewed as both testbed network and testbed system. DRAGON-Lab is an independent AS(autonomous system) and connected to multiple real networks. On the other hand,DRAGON-Lab integrates many resources of its own,partners' and internet's,so as to provide open service. DRAGON-Lab has a large scale,provides open service,supports remote visualized experiments and programmable experiments. More details will be introduced in this paper. | WANG JiLong LI ZhongHui LV GuoHan JIANG CaiPing LI Xing ZHANG QianLi | 2008 | Science in China(Series F)2008，51，11： | 6 |
| 2 | DNA degradation within mouse brain and dental pulp cells 72 hours postmortem显示文摘In this study, we sought to elucidate the process of DNA degradation in brain and dental pulp cells of mice, within postmortem 0-72 hours, by using the single cell gel electrophoresis assay and professional comet image analysis and processing techniques. The frequency of comet-like cells, the percentage of tail DNA, tail length, tail moment, Olive moment and tail area increased in tandem with increasing postmortem interval. In contrast, the head radius, the percentage of head DNA and head area showed a decreasing trend. Linear regression analysis revealed a high correlation between these parameters and the postmortem interval. The findings suggest that the single cell gel electrophoresis assay is a quick and sensitive method to detect DNA degradation in brain and dental pulp cells, providing an objective and accurate new way to estimate postmortem interval. | Jilong Zheng Xiaona Li Di Shan Han Zhang Dawei Guan | 2012 | Neural Regeneration Research2012，7，4： | 5 |
| 3 | Domesticated cynomolgus monkey embryonic stem cells allow the generation of neonatal interspecies chimeric pigs显示文摘Blastocyst complementation by pluripotent stem cell(PSC)injection is believed to be the most promising method to generate xenogeneic organs.However,ethical issues prevent the study of human chimeras in the late embryonic stage of development.Primate embryonic stem cells(ESCs),which have similar pluripotency to human ESCs,are a good model for studying interspecies chimerism and organ generation.However,whether primate ESCs can be used in xenogenous grafts remains unclear.In this study,we evaluated the chimeric ability of cynomolgus monkey(Macaca fascicularis)ESCs(cmESCs)in pigs,which are excellent hosts because of their many similarities to humans.We report an optimized culture medium that enhanced the anti-apoptotic ability of cmESCs and improved the development of chimeric embryos,in which domesticated cmESCs(D-ESCs)injected into pig blastocysts differentiated into cells of all three germ layers.In addition,we obtained two neonatal interspecies chimeras,in which we observed tissue-specific D-ESC differentiation.Taken together,the results demonstrate the capability of D-ESCs to integrate and differentiate into functional cells in a porcine model,with a chimeric ratio of 0.001-0.0001 in different neonate tissues.We believe this work will facilitate future developments in xenogeneic organogenesis,bringing us one step closer to producing tissue-specific functional cells and organs in a large animal model through interspecies blastocyst complementation. | Rui Fu Dawei Yu Jilong Ren Chongyang Li Jing Wang Guihai Feng Xuepeng Wang Haifeng Wan Tianda Li Libin Wang Ying Zhang Tang Hai Wei Li Qi Zhou | 2020 | Protein & Cell2020，11，2： | 4 |
| 4 | Terrain relief periods of loess landforms based on terrain profiles of the Loess Plateau in northern Shaanxi Province,China显示文摘The Loess Plateau is densely covered by numerous types of gullies which represent different soil erosion intensities.Therefore,research on topographic variation features of the loess gullies is of great significance to environmental protection and ecological management.Using a5 m digital elevation model and data from a national geographic database,this paper studies different topographical areas of the Loess Plateau,including Shenmu,Suide,Yanchuan,Ganquan,Yijun,and Chunhua,to derive representative gully terrain profile data of the sampled areas.First,the profile data are standardized in MATLAB and then decomposed using the ensemble empirical mode decomposition method.Then,a significance test is performed on the results;the test confidence is 95% to 99%.The most reliable decomposition component is then used to calculate the relief period and size of the gullies.The results showed that relief periods of the Chunhua,Shenmu,Yijun,Yuanchuan,Ganquan,and Suide gullies are 1110.14 m,1096.85 m,1002.49 m,523.48 m,498.12 m,and 270.83 m,respectively.In terms of gully size,the loess landforms are sorted as loess fragmented tableland,aeolian and dune,loess tableland,loess ridge,loess hill and loess ridge,and loess hill,in descending order.Taken together,the gully terrain features of the sample areas and the results of the study are approximately consistent with the actual terrain profiles.Thus,we conclude that ensemble empirical mode decomposition is a reliable method for the study of the relief and topography of loess gullies. | Jianjun CAO Guoan TANG Xuan FANG Jilong LI Yongjuan LIU Yiting ZHANG Ying ZHU Fayuan LI | 2019 | Frontiers of Earth Science2019，13，2： | 4 |
| 5 | Toxoplasma gondii GRA15II effector-induced M1 cells ameliorate liver fibrosis in mice infected with Schistosomiasis japonica显示文摘Recent studies indicated that type II Toxoplasma gondii(Tg)GRA15II favored the generation of classically activated macrophages(M1),whereas type I/III TgROP16I/III promoted the polarization of alternatively activated macrophages(M2).A number of studies have demonstrated that M2 cells are involved in the pathogenesis of the liver fibrogenesis caused by Schistosoma japonicum.The purpose of the present study was to explore the inhibitory effect of Toxoplasma-derived TgGRA15II on mouse hepatic fibrosis with schistosomiasis.The gra15II and rop16I/III genes were amplified from strains T.gondii PRU and Chinese 1 Wh3,respectively.Lentiviral vectors containing the gra15II or rop16I/III plasmid were constructed and used to infect the RAW264.7 cell line.The polarization of the transfected cells was evaluated,followed by co-culture of the biased macrophages with mouse hepatic stellate JS1 cells.Then,mice were injected with GRA15II-driven macrophages via the tail vein and infected with S.japonicum cercariae.TgGRA15II induced a M1-biased response,whereas TgROP16I/III drove the macrophages to a M2-like phenotype.The in vitro experiments indicated that JS1 cell proliferation and collagen synthesis were decreased following co-culture with TgGRA15II-activated macrophages.Furthermore,mice inoculated with TgGRA15II-biased macrophages displayed a notable alleviation of collagen deposition and granuloma formation in their liver tissues.Our results suggest that TgGRA15II-induced M1 cells may dampen the M2 dominant pathogenesis of hepatic fibrosis and granulomatosis.These results provide insights into the use of parasite-derived immunomodulators as potential anti-fibrosis agents and to re-balance the schistosomiasis-induced immune response. | Yuanyuan Xie Huiqin Wen Ke Yan Shushu Wang Xuesong Wang Jian Chen Yuanling Li Yuanhong Xu Zhengrong Zhong Jilong Shen Deyong Chu | 2018 | Cellular & Molecular Immunology2018，15，2： | 4 |
| 6 | Interface transferring mechanism and error modification of embedded FBG strain sensors显示文摘As the strain sensing element of a structural health monitoring,the study and the application of the fibre-optic bragg grating(FBG)have been widely accepted.The accuracy of the FBG sensor is highly dependent on the physical and the mechanical properties of the strain interface transferring characteristics among the layers of bare optical fibre,protective coating,adhesive layer and host material.In this paper,firstly,the general expression of the multilayer interface strain transferring mechanism is derived.Secondly,based on the defined average strain,the error-modified equation of the FBG sensor is obtained.Finally,in the light of the embedded tube-packaged FBG and the fibre reinforced polymer-optical fibre bragg grating(FRP-OFBG)strain sensors,developed in the Harbin Institute of Technology(HIT),the corresponding strain transferring laws have been studied,and the corresponding error modification coefficients have also been given,which are validated by experiments.The research results provide theories for the development and application of the embedded FBG sensors. | ZHOU Zhi LI Jilong OU Jinping | 2007 | Frontiers of Electrical and Electronic Engineering in China2007，2，1： | 3 |
| 7 | Effect of silicon precursor on silicon incorporation in SAPO-11 and their catalytic performance for hydroisomerization of n-octane on Pt-based catalysts显示文摘SAPO-11 molecular sieves were synthesized using silica sol, hydrophilic fumed silica, and tetraethyl orthosilicate(TEOS) as silicon precursors. Their physicochemical properties were characterized using XRD,SEM, nitrogen adsorption-desorption, Py-IR, NH_3-TPD, EDS, and ^(27)Al,^(31)P,^(29)Si MAS NMR techniques. The catalytic performance was assessed in the hydroisomerization of n-octane. The results showed that the silicon precursors influenced the physicochemical properties and catalytic performance of SAPO-11. SAPO-11 synthesized using hydrophilic fumed silica as silicon precursor showed higher silicon distribution and had more medium acid sites. SAPO-11 synthesized using TEOS as silicon precursor had more silicon content, but more silicon islands formed in its framework. The depolymerization of silicon precursors might affect the silicon content and distribution in SAPO-11. In the hydroisomerization of n-octane, the catalytic activity strongly depended on the number of medium acid sites instead of the number of total acid sites.SAPO-11 synthesized using hydrophilic fumed silica as silicon precursor exhibited higher catalytic activity than the other samples because it has more medium acid sites. | Zhichao Yang Jilong Li Yunqi Liu Chenguang Liu | 2017 | Journal of Energy Chemistry2017，26，4： | 3 |
| 8 | Landform Planation Index Extracted from DEMs: A Case Study in Ordos Platform of China显示文摘Planation surface, a surface that is almost flat, is a kind of low-relief landforms. Planation surface is the consequence of the denudation and planation processes under a tectonic stable condition. The quantitative expression of the characteristics of planation surface plays a key role in reconstructing and describing the evolutionary process of landforms. In this study, Landform Planation Index(LPI), a new terrain derivative, was proposed to quantify the characteristics of planation surface. The LPIs were calculated based on the summit surfaces formed according to the clustering results of peaks. Ten typical areas in the Ordos Platform located in the central part of the Loess Plateau of China are chosen as the test areas for investigating their planation characteristics with the LPI. The experimental results indicate that the LPI can be effectively used to quantify the characteristics of planation surfaces. In addition, the LPI can be further used to depict the patterns of spatial differentiation in the Ordos Platform. Although the present Ordos Platform area is full of the high-density gullies, its planation characteristics is found to be well preserved. Furthermore, the characteristics of the planation surfaces can also reflect the original morphology of the Ordos Platform before the loess dusts deposition process evolved in this area. The statistical results of the LPI show that there is a gradually increasing tendency along with the increasing of slope gradient of summit surface. It indicates that the characteristics of planation surfaces vary among test areas with different landforms. These findings help to deepen the understanding of planation characteristics of the loess landform and its underlying paleotopography. Results of this study can be also served as an important theoretical reference value for revealing the evolutionary process of loess landform. | QIAN Yeqing XIONG Liyang LI Jilong TANG Guoan | 2016 | Chinese Geographical Science2016，26，3： | 3 |
| 9 | Dynamic and Seismic Property Experiments of High Damping Concrete and Its Frame Models显示文摘The loss tangent and storage modulus of cement mortar containing treated silica fume and styrene-acrylic are measured.Shaking table tests on three groups of 1/4 models of high damping concrete frames are conducted to compare the effects of reducing vibration.A relationship between the viscosity coefficient of high damping concrete and the damping coefficient of structure is established by analyzing dynamic parameters like damping ratio and frequency,and comparing responses of relative displacement and absolute acceleration. Surface treatment of silica fume and styrene-acrylic emulsion prior to incorporation in a cement mortar increases the loss tangent of the resulting composite by 40-400% as compared to the cement mortar without any admixtures,and the damping ratio of the reinforced concrete is raised by 7%-9%.In addition,a theoretical method of determining the viscosity coefficient of the material on the basis of shaking table test results is put forward. | 欧进萍 刘铁军 LI Jilong | 2008 | Journal of Wuhan University of Technology(Materials Science)2008，23，1： | 3 |
| 10 | The prognostic significance of non-sentinel lymph node metastasis in cutaneous and acral melanoma patients—A multicenter retrospective study显示文摘Background:Whether non-sentinel lymph node(SLN)-positive melanoma patients can benefit from completion lymph node dissection(CLND)is still unclear.The current study was performed to identify the prognostic role of nonSLN status in SLN-positive melanoma and to investigate the predictive factors of non-SLN metastasis in acral and cutaneous melanoma patients.Methods:The records of 328 SLN-positive melanoma patients who underwent radical surgery at four cancer centers from September 2009 to August 2017 were reviewed.Clinicopathological data including age,gender,Clark level,Breslow index,ulceration,the number of positive SLNs,non-SLN status,and adjuvant therapy were included for survival analyses.Patients were followed up until death or June 30,2019.Multivariable logistic regression modeling was performed to identify factors associated with non-SLN positivity.Log-rank analysis and Cox regression analysis were used to identify the prognostic factors for disease-free survival(DFS)and overall survival(OS).Results:Among all enrolled patients,220(67.1%)had acral melanoma and 108(32.9%)had cutaneous melanoma.The 5-year DFS and OS rate of the entire cohort was 31.5%and 54.1%,respectively.More than 1 positive SLNs were found in 123(37.5%)patients.Positive non-SLNs were found in 99(30.2%)patients.Patients with positive non-SLNs had significantly worse DFS and OS(log-rank P<0.001).Non-SLN status(P=0.003),number of positive SLNs(P=0.016),and adjuvant therapy(P=0.025)were independent prognostic factors for DFS,while non-SLN status(P=0.002),the Breslow index(P=0.027),Clark level(P=0.006),ulceration(P=0.004),number of positive SLNs(P=0.001),and adjuvant therapy(P=0.007)were independent prognostic factors for OS.The Breslow index(P=0.020),Clark level(P=0.012),and number of positive SLNs(P=0.031)were independently related to positive non-SLNs and could be used to develop more personalized surgical strategy.Conclusions:Non-SLN-positive melanoma patients had worse DFS and OS even after immediate CLND than those with non-SLN-negative melanoma.The Breslow index,Clark level,and number of positive SLNs were independent predictive factors for non-SLN status. | Wei Sun Yu Xu JiLong Yang ZhiChao Liao Tao Li Kai Huang Poulam Patel WangJun Yan Yong Chen | 2020 | Cancer Communications2020，40，11： | 2 |
| 11 | Tunable seesaw-like 3D capacitive sensor for force and acceleration sensing显示文摘To address the resource-competing issue between high sensitivity and wide working range for a stand-alone sensor,development of capacitive sensors with an adjustable gap between two electrodes has been of growing interest.While several approaches have been developed to fabricate tunable capacitive sensors,it remains challenging to achieve,simultaneously,a broad range of tunable sensitivity and working range in a single device.In this work,a 3D capacitive sensor with a seesaw-like shape is designed and fabricated by the controlled compressive buckling assembly,which leverages the mechanically tunable configuration to achieve high-precision force sensing(resolution~5.22 nN)and unprecedented adjustment range(by~33 times)of sensitivity.The mechanical tests under different loading conditions demonstrate the stability and reliability of capacitive sensors.Incorporation of an asymmetric seesaw-like structure design in the capacitive sensor allows the acceleration measurement with a tunable sensitivity.These results suggest simple and low-cost routes to high-performance,tunable 3D capacitive sensors,with diverse potential applications in wearable electronics and biomedical devices. | Jilong Ye Fan Zhang Zhangming Shen Shunze Cao Tianqi Jin Xiaogang Guo Zhihong Li Li Lin Yihui Zhang | 2021 | npj Flexible Electronics2021，5，1： | 2 |
| 12 | Spatial diversity and combination technology using amplitude and phase weighting method for phase-coherent underwater acoustic communications显示文摘 | LI Jilong HUANG Minyan CHENG Shuping TAN Qianlin FENG Haihong | 2018 | Chinese Journal of Acoustics2018，37，1： | 2 |
| 13 | MicroRNA-181a-5p enhances cell proliferation in medullary thymic epithelial cells via regulating TGF-β signaling显示文摘在从不同年龄的老鼠的胸腺纸巾的 miRNAs 的表示侧面在我们的以前的学习被表明了。在 miRNA 表达式侧面的综合分析以后,我们证明 miR-181a-5p 的表达式显著地在 thymic 被减少从 10- 的上皮的房间(侦探) 到 19-month-old 鼠标当与那相比在从 1-month-old 的侦探由量的反向的 transcriptase 聚合酶的鼠标锁住反应时。我们在侦探假设了那 miR-181a-5p 可能通过调整一些基因或发信号的小径与年龄相关的胸腺复杂物被联系。测试这个假设,老鼠髓的 thymic 上皮的房间(MTEC1 ) 被使用。有 miR-181a-5p 的 Transfection 模仿支持了 MTEC1 房间的增长,但是没影响 apoptosis。效果被颠倒 miR-181a-5p 的表示什么时候在 MTEC1 房间被压制。而且,转变生长因素贝它受体(Tgfbr1 ) 我被酶试金作为 miR-181a-5p 的一个直接目标证实。而且,它被发现 miR-181a-5p 的那 overexpression 下面调整 Smad3 的 phosphorylation 并且堵住了发信号的转变生长因素贝它的激活。不过,一相反地,关联在 Tgfbr1 的表示之间被观察,在侦探的 miR-181a-5p 源于不同年龄的老鼠。一起,我们提供 miR-181a-5p 可以是在侦探,和表示的增长的一个重要内长的管理者的证据在侦探的 miR-181a-5p 的层次可以与年龄相关的胸腺复杂物被联系。 | Dongguang Guo Yaqiong Ye Junjie Qi Lihua Zhang Lifeng Xu Xiaotong Tan Xiaofang Yu Qihong Liu Jilong Liu Yuan Zhang Yongjiang Ma Yugu Li | 2016 | Acta Biochimica et Biophysica Sinica2016，48，9： | 2 |
| 14 | Exploiting Effective Facial Patches for Robust Gender Recognition显示文摘Gender classification is an important task in automated face analysis. Most existing approaches for gender classification use only raw/aligned face images after face detection as input. These methods exhibit fair classification ability under constrained conditions, in which face images are acquired under similar illumination with similar poses. The performances of these methods may deteriorate when face images show drastic variances in poses and occlusion as routinely encountered in real-world data. The reduction in the performances of current gender classification methods may be attributed to the sensitiveness of features to image translations. This work proposes to alleviate this sensitivity by introducing a majority voting procedure that involves multiple face patches.Specifically, this work utilizes a deep learning method based on multiple large patches. Several Convolutional Neural Networks(CNN) are trained on individual, predefined patches that reflect various image resolutions and partial cropping. The decisions of each CNN are aggregated through majority voting to obtain the final gender classification accurately. Extensive experiments are conducted on four gender classification databases, including Labeled Face in-the-Wild(LFW), CelebA, ColorFeret, and All-Age Faces database, a novel database collected by our group. Each individual patch is evaluated, and complementary patches are selected for voting. We show that the classification accuracy of our method is comparable with that of state-of-the-art systems. This characteristic validates the effectiveness of our proposed method. | Jingchun Cheng Yali Li Jilong Wang Le Yu Shengjin Wang | 2019 | Tsinghua Science and Technology2019，24，3： | 2 |
| 15 | Nuclear transfer using nonquiescent adult fibroblasts from a bovine ear显示文摘The natural reproduction of mammal is sexual reproduction, which needs fertilization involving sperm and oocyte. Nuclear transfer provided an asexual reproduction method for mammal. Donor cells used in previous experiments of nuclear transfer were mostly from undif-ferentiated or non-terminally differentiated cells, such as embryonic or fetal cells. However, since Wilmut et al. obtained a viable lamb by transfer of an adult sheep somatic cell into | Jilong Liu Minkang Wang Li Lian Jinsong Li Shaorong Gao Zhiming Han Qingyuan Sun Xiangfen Song Dongmei Zhang Yihai Li et al. | 1999 | Chinese Science Bulletin1999，44，21： | 2 |
| 16 | Acidity-triggered TAT-presenting nanocarriers augment tumor retention and nuclear translocation of drugs显示文摘 | Wei Jiang Jilong Wang Jinbin Yang Zhiwei He Zhenhui Hou Yingli Luo Li Wang Jing Liu Houbing Zhang Yangyang Zhao Guoqing Zhang Fang Huang Xuechang Zhou Lifeng Yan Xianzhu Yang Yucai Wang Jun Wang | 2018 | Nano Research2018，11，10： | 2 |
| 17 | Paeoniflorin:a monomer from traditional Chinese medical herb ameliorates Schistosoma Japonicum egg-induced hepatic fibrosis in mice显示文摘 | Xiaoyue Li Jilong Shen Zhengrong Zhong | | 0，，05： | 1 |
| 18 | Paeoniflorin ameliorates schistosomiasis liver fibrosis through regulating IL-13 and its signaling molecules in mice显示文摘 | Xiaoyue Li Jilong She n Zhengrong Zhong | | 0，，： | 1 |
| 19 | Satellite-detected fronts and butterfish aggregations in the northeastern Gulf of Mexico显示文摘 | Herron Rex C Leming Thomas D Li Jilong | 1989 | Continental Shelf Research1989，9，6： | 1 |
| 20 | An On-chip Interconnection QoS Verification Platform of Processor of Large Data for Architectural Modeling Analysis显示文摘This paper presents introduction for a QoS verification of on-chip interconnection based on the new progress of the industry, which combined with an AMD processor chip design for big data. Some verification experience in architectural modeling and simulation of on-chip interconnection is also introduced in this paper. | Li Qinghua Qin Jilong Ding Xu Wang Endong Gong Weifeng | 2015 | 国际计算机前沿大会会议论文集2015，，1： | 1 |
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