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| 1 | 健康老年妇女近段股骨骨密度和结构的定量CT研究显示文摘目的采用定量CT(QCT)和双能X线吸收测量(DXA)仪对健康老年妇女近段股骨骨密度(BMD)和骨结构进行研究,并对2种测量方法的结果进行比较。方法对66名65岁以上健康妇女左侧髋关节进行DXA测量,计算出股骨颈和粗隆区BMD;对其双侧近段股骨进行QCT测量,计算出股骨颈、粗隆区和整体股骨ROI的皮质骨、松质骨和总体骨的BMD和体积;并将QCT三维图像模拟DXA的平面投影计算出模拟DXA股骨颈BMD和模拟DXA股骨粗隆区BMD。对所获数据进行配对t检验或非参数秩和检验,并用Pearson法分析DXA和QCT相对应ROI的相关性。结果用QCT可以对股骨近段不同ROI(股骨颈、粗隆区和整体股骨区)及不同骨成分(皮质骨、松质骨和总体骨)的BMD及体积等参数进行精确的定量分析。除右侧股骨颈皮质骨BMD[(0.52±0.04)g/cm^3]、股骨粗隆区皮质骨BMD[(0.49±0.03)g/cm^3]、股骨粗隆区综合骨BMD[(0.22±0.04)g/cm^3]大于左侧相应参数[分别为[(0.51±0.04)、(0.48±0.03)、(0.21±0.04)g/cm^3],差异均有统计学意义(P值均〈0.05),但差别均〈3.3%;而模拟DXA股骨颈BMD、模拟DXA股骨粗隆区BMD、股骨颈皮质骨体积、股骨颈松质骨BMD、股骨颈松质骨体积、股骨颈综合骨BMD、股骨颈综合骨体积、股骨粗隆区皮质骨体积、股骨粗隆区松质骨BMD、股骨粗隆区松质骨体积、股骨粗隆区综合骨体积左侧参数分别为(0.52±0.10)g/cm^2、(0.78±0.13)g/cm^2、5.80cm^3、(0.06±0.03)g/cm^3、(5.19±1.40)cm^3、(0.25±0.04)g/cm^3、15.66cm^3、(21.74±3.43)cm^3、(0.08±0.03)g/cm^3、(34.27±6.09)cm^3、(76.12±11.11)cm^3,右侧分别为(0.52±0.10)g/cm^2、(0.78±0.13)g/cm^2、6.01cm^3、(0.06±0.02)g/cm^3、(5.17±1.27)cm^3、(0.25±0.04)g/cm^3、15.62cm^3、(22.12±3.60)cm^3、(0.09±0.03)g/cm^3、(34.17±5.94)cm^3、(76.53±10.71)cm^3,差异均无统计学意义(P值均〉0.05)。左右两侧近段股骨QcT各相对应参数之间的r值范围在0.656~0.955,均具有相关性(P〈0.05)。QcT模拟DXA股骨颈和粗隆区BMD与真正DXA测量的相应值之间r值分别为0.685和0.855,具有相关性(P〈0.05)。结论利用QCT技术可以对老年妇女近段股骨不同区域和不同成分的BMD和结构进行精确定量分析,QCT是骨质疏松研究中非常有用的测量技术。 | 程晓光 Li Jing 刘霞 王予生 李谨 屈辉 H Genant T Lang | 2009 | 中华放射学杂志2009，43，2： | 8 |
| 2 | Hematological disorders and pulmonary hypertension显示文摘Pulmonary hypertension(PH),a serious disorder with a high morbidity and mortality rate,is known to occur in a number of unrelated systemic diseases.Several hematological disorders such as sickle cell disease,thalassemia and myeloproliferative diseases develop PH which worsens the prognosis.Associated oxidant injury and vascular inflammation cause endothelial damage and dysfunction.Pulmonary vascular endothelial damage/dysfunction is an early event in PH resulting in the loss of vascular reactivity,activation of proliferative and antiapoptotic pathways leading to vascular remodeling,elevated pulmonary artery pressure,right ventricular hypertrophy and premature death.Hemolysis observed in hematological disorders leads to free hemoglobin which rapidly scavenges nitric oxide(NO),limiting its bioavailability,and leading to endothelial dysfunction.In addition,hemolysis releases arginase into the circulation which converts L-arginine to ornithine,thus bypassing NO production.Furthermore,treatments for hematological disorders such as immunosuppressive therapy,splenectomy,bone marrow transplantation,and radiation have been shown to contribute to the development of PH.Recent studies have shown deregulated iron homeostasis in patients with cardiopulmonary diseases including pulmonary arterial hypertension(PAH).Several studies have reported low iron levels in patients with idiopathic PAH,and iron deficiency is an important risk factor.This article reviews PH associated with hematological disorders and its mechanism:and iron homeostasis and its relevance to PH. | Rajamma Mathew Jing Huang Joseph M Wu John T Fallon Michael H Gewitz | 2016 | World Journal of Cardiology2016，8，12： | 6 |
| 3 | Advances in dye-sensitized solar cell显示文摘THE conversion of visible light to electricity using semiconductors as light absorbers has beenan important area of research for many years. In the 1970s, highly efficient photovoltaiccells based on silicon were developed (the light-to-electrical conversion efficiency≥25%),which provides energy to aircrafts. Then semiconductor liquid-junction photoelectrochemicalcell started to be investigated. Generally speaking, highly efficient liquid-junction photoelec-trochemical solar cells can be obtained by using semiconductors such as Si, GaAs and WSe.(band gap≈(1.3±0.3) eV). Conversion efficiencies over 15% have been acquired on solarcells consisting of single crystals of Si or GaAs. But the serious photocorrosion and high | Jing, BW Zhang, MH Shen, T | 1997 | Chinese Science Bulletin1997，42，23： | 6 |
| 4 | RFP-mediated ubiquitination of PTEN modulates its effect on AKT activation显示文摘PTEN 肿瘤 suppressor 是在调整 phosphatidylinositol-3-kinase (PI3K ) 有一个中央角色的类脂化合物磷酸酶信号 transduction 串联。不过, PTEN 活动被在房间调整的机制需要进一步的说明。尽管以前的研究证明了 PTEN 的 ubiquitination 能调制它的稳定性和 subcellular 本地化,在 PTEN 功能的最批评的方面的 ubiquitination 的角色,它的磷酸酶活动,充分没被探讨。这里,我们识别 PTEN 的新奇 E3 ubiquitin ligase,沤手指蛋白质(RFP ) ,那能支持 PTEN 的不正常的 polyubiquitinations。这些 ubiquitinations 不导致 PTEN 不稳定性或本地化,但是相当显著地禁止 PTEN 磷酸酶活动因此调制它的能力调整 PI3K 信号 transduction 串联。确实, RFP overexpression 在 AKT 激活上减轻调停 PTEN 的禁止的效果;相反,调停 RNAi 内长的 RFP 击倒提高 PTEN 的能力压制 AKT 激活。而且, PTEN 的调停 RFP 的 ubiquitination 禁止小道表示的 PTEN 依赖的激活并且也压制它的能力导致 apoptosis。我们的调查结果在控制 PTEN 表明调停 RFP 的 ubiquitination 的一个关键角色活动。 | James T Lee Jing Shan Jiayun Zhong Muyang Li Brenda Zhou Amanda Zhou Ramon Parsons Wei Gu | 2013 | Cell Research2013，23，4： | 5 |
| 5 | Effects of sewage sludge Cd concentration on chemical extractability and plant uptake显示文摘 | Jing J Logon T J | 1992 | J Environ Qual1992，21，： | 2 |
| 6 | A new SPD process for spheroidal cast iron显示文摘 | Zhao X Jing T F Gao Y W | 2004 | Materials Letters2004，58，： | 1 |
| 7 | Detection of low observable target within sea clutter by structure function based multifractal analysis显示文摘 | Jing H Wenwen T Gao J B | 2006 | IEEE Transaction on Antennas and Propagation2006，54，1： | 1 |
| 8 | SUMO1 polymorphisms are associated with non-syndromic cleft lip with or without cleft palate显示文摘 | Song T Li G Jing G | 2008 | Biochem Biophys Res Commun2008，377，4： | 1 |
| 9 | Meticulously detailed eye region model and its application to analysis of facial images 显示文摘 | Moriyama T Kanade T Xiao Jing | 2006 | IEEE Transactions on Pattern Analysis and Machine Intelligence2006，28，5： | 1 |
| 10 | Metal porphyrin/phenyltrimethylammonium tribromidc:High efficient catalysts for coupling reaction of CO2 and epoxides显示文摘 | JIN L L JING H W CHANG T | 2007 | Journal of Molecular Catalysis(A) : Chemical2007，261，： | 1 |
| 11 | Large-eddy simulations (LES) of temperature fluctuations in a mixing tee with/without a porous medium 显示文摘 | LU T JING P X GAO Z J ZHANG Y W | 2007 | Int J of Heat and Mass Transfer2007，53，2122： | 1 |
| 12 | Local structure based supervised feature extraction 显示文摘 | ZHAO H T SUN S Y JING Z L | 2006 | Pattern Reognition2006，39，88： | 1 |
| 13 | Proteome Approach to Identify Wound-Respnse Related Proteins from Rice Leaf Sheath 显示文摘 | SHEN S JING Y KUANG T | 2003 | Protemoics2003，3，4： | 1 |
| 14 | Inhibitory effects of angiotensin on NMDA-induced cytotoxicity in primary neuronal cultures显示文摘 | Jing G Grammatopoulos T Ferguson P | 2004 | Brain Res Bull2004，62，5： | 1 |
| 15 | Fuzzy-decisionmaking problems of fuel ethanol production using a genetically engineered yeast显示文摘 | Wang F S Jing C H Tsao G T | 1998 | Industrial & Engineering Chemistry Research1998，37，8： | 1 |
| 16 | Anal Chim Acta显示文摘 | Jing T Xia H Guan Q Lu W H Dai Q Niu J W Lim J M Hao Q L Lee Y Zhou Y K Mei S R | 2011 | 692:732011，692，： | 1 |
| 17 | Ephrin-A1-mediated dopaminergic neurogenesis and angiogenesis in a rat model of Parkinson's disease显示文摘 | Jing X Miwa H Sawada T | 2012 | PLo S One2012，7，32： | 1 |
| 18 | Magnetic molecularly imprinted nanoparticles for recognition of lysozyme显示文摘 | Jing T Du H Dai Q | 2010 | Biosensors and Bioelectronics2010，26，2： | 1 |
| 19 | Sensitization and apoptosis augmentation of K562/ADM cells by anti-multidrug resistance gene peptide nucleic acid and antisense oligodeoxyribonucleotide 显示文摘 | Wei H L Wu Y J Jing T | 2003 | Acta Pharmacol Sin2003，24，8： | 1 |
| 20 | The long protective rust layer formed on weathering steel by atmospheric corrosion during a quarter of a century 显示文摘 | Jing Gui Deuine T term growth of the M | 1994 | Corros Sci1994，34，4： | 1 |
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