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| 1 | Non-alcoholic fatty liver disease and the metabolic syndrome:An update显示文摘Sedentary lifestyle and poor dietary choices are leading to a weight gain epidemic in westernized countries, subsequently increasing the risk for developing the metabolic syndrome and nonalcoholic fatty liver disease (NAFLD). NAFLD is estimated to affect approximate 30% of the general US population and is considered the hepatic manifestation of the metabolic syndrome. Recent findings linking the components of the metabolic syndrome with NAFLD and the progression to nonalcoholic steatohepatitis (NASH) will be reviewed; in particular, the role of visceral adipose tissue, insulin resistance, and adipocytokines in the exacerbation of these conditions. While no therapy has been proven effective for treating NAFLD/NASH, common recommendations will be discussed. | R Scott Rector John P Thyfault Yongzhong Wei Jamal A Ibdah | 2008 | World Journal of Gastroenterology2008,14,2: | 60 |
| 2 | Anterior muscle sparing approach for total hip arthroplasty显示文摘The purpose of this review is to examine the validity of positive claims regarding the direct anterior approach(DAA) with a fracture table for total hip arthroplasty. Recent literature regarding the DAA was searched and specific claims investigated including improved early outcomes, speed of recovery, component placement, dislocation rates, and complication rates. Recent literature is positive regarding the effects of total hip arthroplasty with the anterior approach. While the data is not definitive at present, patients receiving the anterior approach for total hip arthroplasty tend to recover more quickly and have improved early outcomes. Component placement with the anterior approach is more often in the 'safe zone' than with other approaches. Dislocation rates tend to be less than 1% with the anterior approach. Complication rates vary widely in the published literature. A possible explanation is that the varianceis due to surgeon and institutional experience with the anterior approach procedure. Concerns remain regarding the 'learning curve' for both surgeons and institutions. In conclusion, it is not a matter of should this approach be used, but how should it be implemented. | Joseph T Moskal Susan G Capps John A Scanelli | 2013 | World Journal of Orthopedics2013,4,1: | 47 |
| 3 | Nonalcoholic fatty liver disease and mitochondrial dysfunction显示文摘Nonalcoholic fatty liver disease (NAFLD) includes hepatic steatosis, nonalcoholic steatohepatitis (NASH), fibrosis, and cirrhosis. NAFLD is the most common liver disorder in the United States and worldwide. Due to the rapid rise of the metabolic syndrome, the prevalence of NAFLD has recently dramatically increased and will continue to increase. NAFLD has also the potential to progress to hepatocellular carcinoma (HCC) or liver failure. NAFLD is strongly linked to caloric overconsumption, physical inactivity, insulin resistance and genetic factors. Although significant progress in understanding the pathogenesis of NAFLD has been achieved in years, the primary metabolic abnormalities leading to lipid accumulation within hepatocytes has remained poorly understood. Mitochondria are critical metabolic organelles serving as 'cellular power plants'. Accumulating evidence indicate that hepatic mitochondrial dysfunction is crucial to the pathogenesis of NAFLD. This review is focused on the significant role of mitochondria in the development of NAFLD. | Yongzhong Wei R Scott Rector John P Thyfault Jamal A Ibdah | 2008 | World Journal of Gastroenterology2008,14,2: | 32 |
| 4 | Cardiac remodeling and physical training post myocardial infarction显示文摘After myocardial infarction(MI), the heart undergoes extensive myocardial remodeling through the accumulation of fibrous tissue in both the infarcted and noninfarcted myocardium, which distorts tissue structure, increases tissue stiffness, and accounts for ventricular dysfunction. There is growing clinical consensus that exercise training may beneficially alter the course of post-MI myocardial remodeling and improve cardiac function. This review summarizes the present state of knowledge regarding the effect of post-MI exercise training on infarcted hearts. Due to the degree of difficulty to study a viable human heart at both protein and molecular levels, most of the detailed studies have been performed by using animal models. Although there are some negative reports indicating that post-MI exercise may further cause deterioration of the wounded hearts, a growing body of research from both human and animal experiments demonstrates that post-MI exercise may beneficially alter the course of wound healing and improve cardiac function. Furthermore, the improved function is likely due to exercise training-induced mitigation of reninangiotensin-aldosterone system, improved balance between matrix metalloproteinase-1 and tissue inhibitor of matrix metalloproteinase-1, favorable myosin heavy chain isoform switch, diminished oxidative stress, enhanced antioxidant capacity, improved mitochondrial calcium handling, and boosted myocardial angiogenesis. Additionally, meta-analyses revealed that exercise-based cardiac rehabilitation has proven to be effective, and remains one of the least expensive therapies for both the prevention and treatment of cardiovascular disease, and prevents re-infarction. | Michael A Garza Emily A Wason John Q Zhang | 2015 | World Journal of Cardiology2015,7,2: | 28 |
| 5 | Ligation-assisted endoscopic mucosal resection of gastric heterotopic pancreas显示文摘Heterotopic pancreas is a congenital anomaly characterized by ectopic pancreatic tissue.Treatment of heterotopic pancreas may include expectant observation,endoscopic resection or surgery.The aim of this report was to describe the technique of ligation-assisted endoscopic mucosal resection(EMR) for resection of heterotopic pancreas of the stomach.Two patients(both female,mean age 32 years) were referred for management of gastric subepithelial tumors.Endoscopic ultrasound in both disclosed small hypoechoic masses in the mucosa and submucosa.Band ligation-assisted EMR was performed in both cases without complications.Pathology from the resected tumors revealed heterotopic pancreas arising from the submucosa.Margins were free of pancreatic tissue.Ligation-assisted EMR is technically feasible and may be considered for the endoscopic management of heterotopic pancreas. | Mouen A Khashab Oscar W Cummings John M DeWitt | 2009 | World Journal of Gastroenterology2009,15,22: | 25 |
| 6 | Role of liver transplantation in the management of hepatoblastoma in the pediatric population显示文摘Hepatoblastoma(HB) is the most common primary liver tumor in children and accounts for two-thirds of all malignant liver neoplasms in the pediatric population. For patients with advanced HB(unresectable or unresponsive to chemotherapy), combined treatment with chemotherapy and liver transplantation is an excellent option. The etiology of HB is mostly obscure because of its extreme rarity although some inherited syndromes and very low birth weight have been associated with it. The prognosis for children with HB has significantly improved in the past three decades thanks to advancements in chemotherapy, surgical resection and postoperative care. In 2002 a surgical staging system called pretreatment extent of disease(PRETEXT) was designed to allow a universal, multidisciplinary approach to patients with HB. Between one-third to two-thirds of patients initially present with unresectable tumors or distant metastases, but up to 85% of these tumors become operable after neoadjuvant chemotherapy. Patients with PRETEXT categories 1, 2, and some 3 are referred for neoadjuvant chemotherapy followed by surgical resection with the goal of complete tumor removal. Classic treatments regimens include a combination of cisplatin, fluorouracil, and vincristine or cisplatin and doxorubicin. Liver transplantation is the only treatment option for unresectable HB. In 2010 the pediatric end-stage liver disease, a pediatric-specific scoring system that determines a patient's ranking on the liver transplant list, began to award additional 'exception' points for patients with HB. We analyzed the Standard Transplant Analysis and Research dataset to assess the impact of changes in exception point criteria for HB on outcomes after liver transplantation at Texas Children's Hospital in Houston, Texas. We found that patients who were listed for transplantation with current HB exception criteria experienced a shorter waitlist time but survival was similar between the two eras. | Saira Khaderi Jacfranz Guiteau Ronald T Cotton Christine O'Mahony Abbas Rana John A Goss | 2014 | World Journal of Transplantation2014,4,4: | 23 |
| 7 | 基于不同评价方法的绿洲棉田土壤质量综合评价显示文摘【目的】了解新疆绿洲棉田土壤质量状况。【方法】采集新疆主要棉区1 355个土壤样品,测定其pH值、含盐量、黏粒量、土壤有机质、全氮、速效磷、速效钾、有效硫、有效铜、有效锌、土壤重金属全量铬、铜、锌、砷、铅、重金属有效铬、有效砷、有效铅、氟乐灵残留量、二甲戊乐灵残留量以及农膜残留量共21项指标,采用模糊综合评价法(FCE)、基于内梅罗综合污染指数的加权综合污染指数法(N-PI)及土壤综合质量指数评价方法(SQI)分别对绿洲棉田土壤质量进行了综合评价,并对其评价结果进行了比较分析。【结果】新疆绿洲棉田土壤呈碱性,含盐量均值为3.44 g/kg,为轻度盐化土壤,有机质和全氮均偏低,速效磷、速效钾、有效硫及微量元素有效锌、有效铜较为丰富;Cr、Cu、Zn、As、Pb等5种重金属均未超过国家二级标准,但与新疆土壤元素背景值作比较均有累积现象;棉田土壤中重金属有效态Cr、As、Pb、氟乐灵残留及二甲戊乐灵残留量均在适宜范围内,农膜残留量均值为190.98 kg/hm2,农膜污染较为严重。利用FCE法对土壤进行评价,发现绿洲棉田土壤平均质量低;N-PI法对土壤进行综合评价,表明大部分棉田土壤已受轻度污染;利用SQI法进行评价,发现土壤质量综合指标值SQI介于0.31~0.73之间,绿洲棉田土壤综合质量总体中等偏低。不同评价方法得出的评价结果有差异,在本研究中SQI法为最优的评价方法,其评价结果更为客观、科学,符合新疆绿洲棉田土壤质量的实际状况。【结论】新疆棉区土壤质量总体较差,采用通用的评价方法对其进行综合评价,SQI评价法最合理,FCE和N-PI评价法次之。 | 郑琦 王海江 董天宇 吕新 John A Yunger 冉丁 戴第伟 | 2019 | 灌溉排水学报2019,38,3: | 20 |
| 8 | 基于支持向量机的土壤主要盐分离子高光谱反演模型显示文摘快速、无损、定量地获取土壤盐分离子组成及含量是盐渍化土壤治理、改良和利用的重要依据。以新疆盐渍化土壤为研究对象,应用高光谱分析技术获取不同区域土壤盐分离子的特征光谱,在对光谱数据去噪、数据变换基础上分析了鲜样(T1)、风干(T2)和干燥(T3)3类土壤,过2、1、0.15 mm筛处理对离子含量光谱拟合模型精度的影响,建立了基于支持向量机的土壤主要盐分离子光谱反演模型,并对模型的精度和普适性进行了检验。结果表明:土壤原始特征光谱与盐分离子含量均不存在显著相关性,最大相关系数为Na+的0.41;通过光谱数据变换能够明显增强特征波段与离子含量的相关性,K+、Na+、Mg2+、Ca2+、SO_4^(2-)、Cl-和HCO-3的最优变换形式分别为(lgR)'、(lgR)'、R'、(lgR)'、CR、R'和CR,T1处理构建的拟合模型均不能很好地反演离子含量,T3处理的模型估测精度优于T2,土壤粒径越细对土壤离子含量的光谱反演效果越好。分析各处理模型的决定系数和标准误差表明,经T3处理、过0.15 mm筛所构建的离子拟合模型预测精度最高,其中K^+、Na^+、Ca2+和SO_4^(2-)的RPD分别为2.153、2.674 5、2.051和2.786 4,以未参与建模和检验的石河子垦区土样对4种离子模型的普适性检验,其R2分别为0.621 4、0.689 7、0.614 4和0.650 7,说明构建的模型适于估算该区域土壤K+、Na+、Ca2+和SO_4^(2-)的含量。 | 王海江 蒋天池 YUNGER John A 李亚莉 田甜 王金刚 | 2018 | 农业机械学报2018,49,5: | 17 |
| 9 | Visceral hypersensitivity and electromechanical dysfunction as therapeutic targets in pediatric functional dyspepsia显示文摘Functional gastrointestinal disorders(FGID) are common clinical syndromes diagnosed in the absence of biochemical,structural,or metabolic abnormalities. They account for significant morbidity and health care expenditures and are identifiable across variable age,geography,and culture. Etiology of abdominal pain associated FGIDs,including functional dyspepsia(FD),remains incompletely understood,but growing evidence implicates the importance of visceral hypersensitivity and electromechanical dysfunction. This manuscript explores data supporting the role of visceral hypersensitivity and electromechanical dysfunction in FD,with focus on pediatric data when available,and provides a summary of potential therapeutic targets. | John M Rosen Jose T Cocjin Jennifer V Schurman Jennifer M Colombo Craig A Friesen | 2014 | World Journal of Gastrointestinal Pharmacology and Therapeutics2014,5,3: | 16 |
| 10 | Potential Toxicological and Cardiopulmonary Effects of PM2,5 Exposure and Related Mortality:Findings of Recent Studies Published during 2003-2013显示文摘INTRODUCTION Air pollution has become a serious environmental issue owing to its diverse harmful effects on the physical and biological environment.According to the Environmental Protection Agency(EPA)and the World Health Organization(WHO)[1-2],air pollution affects millions of people worldwide.Hundreds of thousands of deaths each year and a range of diseases, | Mohammed O.A.Mohammed SONG Wei Wei MA Wan Li LI Wen Long LI Yi Fan Afed Ullah Khan Mohammed A.E.M.Ibrahim Osman Adam Maarouf Alshebli A Ahmed John J.Ambuchi | 2016 | Biomedical and Environmental Sciences2016,29,1: | 16 |
| 11 | 内侧固定平台单髁置换术后的冠状面下肢力线是翻修的影响因素显示文摘膝关节单髁置换术(unicompartmental knee arthroplasty,UKA)后患者冠状面的下肢力线被认为是影响手术长期疗效的一个重要因素,但关于最佳的UKA术后下肢力线还没有形成明确共识。一些研究主张术后下肢力线应保持在中立位,而另一些研究认为即使术后下肢力线存在10°的内翻也可获得良好的临床效果。 | Sean E Slaven John P Cody Robert A Sershon Henry Ho Robert H Hopper Jr Kevin B Fricka 李亚坤(整理) 张民(整理) | 2020 | 实用骨科杂志2020,26,12: | 15 |
| 12 | Biliary wound healing, ductular reactions, and IL-6/gp130 signaling in the development of liver disease显示文摘在胆汁的树上的 Basic 和翻译创伤愈合研究在皮和胃肠道上在类似的研究后面显著地落后。这是至少对为学习的胆道的容易的存取的缺乏部分可归因。但是临床的关联,对胆汁的上皮的房间(BEC ) 的更多的兴趣 BEC 文化的病理生理学,和普遍可获得性是颠倒这个趋势的因素。在额外肝的胆汁的树上,徒劳的创伤愈合,结疤,苛评开发紧迫发出。在损害的最小的 intra 肝的胆汁管任何一个, BEC 增长或繁的回答能贡献肝疾病。在大、小的胆汁管的慢性炎和坚持的创伤愈合反应经常导致肝癌症。当他们适用于胆道,依赖于表明小径的 IL-6/gp130/STAT3 的细胞的过程的重要性,未答复的问题,和未来方向,愈合的创伤的一般概念被讨论。 | A J Demetris John G Lunz Ⅲ Susan Specht Isao Nozaki | 2006 | World Journal of Gastroenterology2006,12,22: | 15 |
| 13 | Beyond the Pediatric end-stage liver disease system: Solutions for infants with biliary atresia requiring liver transplant显示文摘Biliary atresia(BA), a chronic progressive cholestatic disease of infants, is the leading cause for liver transplant in children, especially in patients under two years of age. BA can be successfully treated with the Kasai portoenterostomy; however most patients still require a liver transplant, with up to one half of BA children needing a transplant by age two. In the current pediatric end-stage liver disease system, children with BA face the risk of not receiving a liver in a safe and timely manner. In this review, we discuss a number of possible solutions to help these children. We focus on two general approaches:(1) preventing/delaying need for transplantation, by optimizing the success of the Kasai operation; and(2) expediting transplantation when needed, by performing techniques other than the standard deceased-donor, whole, ABO-matched organ transplant. | Mary Elizabeth M Tessier Sanjiv Harpavat Ross W Shepherd Girish S Hiremath Mary L Brandt Amy Fisher John A Goss | 2014 | World Journal of Gastroenterology2014,20,32: | 14 |
| 14 | Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells显示文摘外长的 dopaminergic 神经原(DA 神经原) 的移植是为治疗 Parkinson 的疾病(PD ) 的一条有希望的途径。然而,主要跌倒块是施主 DA 神经原的可靠来源的缺乏。这里,我们证明五 transcriptional 因素 Mash1, Ngn2, Sox2, Nurr1,和 Pitx3 的联合直接并且有效地装改编人成纤维细胞进 DA 像神经原的房间。为为 DA 神经原的各种各样的标记积极的染色的 reprogrammed 房间。他们也显示出典型 DA 举起和生产性质。而且,他们展出了 DA 神经原特定的 electrophysiological 侧面。最后,他们在一个老鼠 PD 模型提供了征兆的地势。因此,我们的直接 reprogrammed DA 像神经原的房间是为 PD 的房间代替治疗的有希望的来源。 | Xinjian Liu Fang Li Elizabeth A Stubblefield Barbara Blanchard Toni L Richards Gaynor A Larson Yujun He Qian Huang Aik-Choon Tan Dabing Zhang Timothy A Benke John R Sladek Nancy R Zahniser Chuan-Yuan Li | 2012 | Cell Research2012,22,2: | 14 |
| 15 | 肌萎缩性侧索硬化蛋白激活小胶质细胞NLRP3炎性小体显示文摘小胶质细胞NLRP3炎性小体激活正在成为神经退行性变过程中神经炎症的关键因素。诸如β-淀粉样蛋白和α-突触核蛋白之类的致病性蛋白质聚集体触发小胶质NLRP3激活,从而导致半胱天冬酶-1激活和IL-1β的分泌。在小鼠肌萎缩性侧索硬化症(ALS)的SOD1G93A模型中,半胱天冬酶-1和IL-1β均促进疾病进展,提示小胶质NLRP3在该进程中发挥作用。然而先前的研究表明,SOD1G93A小鼠小胶质细胞不表达NLRP3,SOD1G93A蛋白在小胶质细胞中产生独立于NLRP3的IL-1β。本研究论证了使用Nlrp3-GFP基因敲入小鼠,在SOD1G93A小鼠中小胶质细胞表达NLRP3。本研究显示聚集和可溶性SOD1G93A均可激活小鼠原代小胶质细胞中的炎性小体,导致半胱天冬酶-1和IL-1β裂解,ASC斑点形成以及呈剂量和时间依赖性的IL-1β分泌。重要的是,SOD1G93A无法从缺乏Nlrp3的小胶质细胞或者用特异性NLRP3抑制剂MCC950预处理的小胶质细胞中诱导IL-1β分泌,从而证实NLRP3是介导SOD1诱导的小胶质细胞IL-1β分泌的关键炎症小体复合物。在TDP-43Q331K ALS小鼠模型中也观察到小胶质NLRP3上调,TDP-43野生型和突变蛋白亦可以NLRP3依赖性的方式激活小胶质炎性小体。从机制上讲,本研究确定了活性氧簇和ATP的生成是SOD1G93A介导的NLRP3激活所需的关键事件。总之,本研究的数据表明ALS小胶质细胞表达NLRP3,而病理ALS蛋白激活小胶质NLRP3炎性小体。因此,NLRP3抑制可能是阻止小胶质细胞神经炎症和ALS疾病进展的潜在治疗方法。 | Vandana Deora John D Lee Eduardo AAlbornoz Luke McAlary Cyril J Jagaraj Avril A B Robertson Julie D Atkin Matthew A Cooper Kate Schroder Justin J Yerbury Richard Gordon Trent MWoodruff 杜一星(编译) | 2020 | 神经损伤与功能重建2020,15,9: | 13 |
| 16 | China Patient-centered Evaluative Assessment of Cardiac Events Prospective Study of Acute Myocardial Infarction: Study Design显示文摘 | Rachel P Dreyer Xi Li Xue Du Nicholas S Downing Li Li Hai-Bo Zhang Fang Feng Wen-Chi Guan Xiao Xu Shu-Xia Li Zhen-Qiu Lin Frederick A Masoudi John A Spertus Harlan M Krumholz Li-Xin Jiang | 2016 | Chinese Medical Journal2016,,1: | 13 |
| 17 | 不同粒径处理的土壤全氮含量高光谱特征拟合模型显示文摘采集新疆北疆棉田385个自然土壤样本,将筛选出的土壤样品分别过2、1、0. 5、0. 15 mm筛并测定其原始光谱反射率,利用支持向量机(Support vector machine,SVM)、偏最小二乘回归(Partial least squares regression,PLSR)和多元逐步线性回归(Stepwise multiple linear regression,SMLR)方法对土壤原始光谱及其12种光谱变换数据分别构建土壤全氮含量的估测模型,并对模型精度进行检验。结果表明,土壤原始光谱特征在各个波段与全氮含量相关性都较差,不同形式的数据变换均能够提高光谱反射率与全氮含量的相关性,同一种数据变换形式在不同粒径处理中最大相关系数所对应的波段位置差异不大。从不同粒径处理的拟合精度来看,过筛粒径越小对全氮含量的估测精度越高,3种方法的最优拟合模型都是过0. 15 mm筛的处理,其中SVM方法采用(lgR)'变换后,构建模型R2c为0. 898 7,RMSEc为0. 018 1,RPD为2. 704 9,PLSR和SMLR方法均采用R'变换,构建模型的R2c分别为0. 852 0和0. 819 6,RMSEc分别为0. 041 3和0. 043 6,RPD分别为2. 554 9和2. 437 4,3种方法在该过筛处理下均能够很好地估测土壤全氮含量。用未参与建模的样本对3种最优模型进行验证,SVM、PLSR和SMLR模型的检验R2分别为0. 822 9、0. 771 5和0. 705 4,SVM方法优于PLSR和SMLR,模型具有较好的精度和稳定性,从模型的预测误差来看,土壤全氮含量越低其预测误差也越大,在氮素含量较低的情况下无法直接通过光谱反射特征准确反演。 | 王海江 刘凡 YUNGER John A 崔静 马玲 | 2019 | 农业机械学报2019,50,2: | 13 |
| 18 | Magnetic anchor guidance for endoscopic submucosal dissection and other endoscopic procedures显示文摘Endoscopic submucosal dissection(ESD) is a wellestablished, minimally invasive treatment for superficial neoplasms of the gastrointestinal tract. The universal adoption of ESD has been limited by its slow learning curve, long procedure times, and high risk of complications. One technical challenge is the lack of a second hand that can provide traction, as in conventional surgery. Reliable tissue retraction that exposes the submucosal plane of dissection would allow for safer and more efficient dissection. Magnetic anchor guided endoscopic submucosal dissection(MAGESD) has potential benefits compared to other current traction methods. MAG-ESD offers dynamic tissue retraction independent of the endoscope mimicking a surgeon's 'second hand'. Two types of magnets can be used: electromagnets and permanent magnets. In this article we review the MAG-ESD technology, published work and studies of magnets in ESD. We also review the use of magnetic anchor guidance systems in natural orifice transluminal endoscopic surgery and the idea of magnetic non-contact retraction using surface ferromagentization. We discuss the current limitations, the future potential of MAG-ESD and the developments needed for adoption of this technology. | Mohamed Mortagy Neal Mehta Mansour A Parsi Seiichiro Abe Tyler Stevens John J Vargo Yutaka Saito Amit Bhatt | 2017 | World Journal of Gastroenterology2017,23,16: | 12 |
| 19 | 故障一点通显示文摘通用 行驶时SIR(辅助充气式气囊保护)警告灯点亮 对1999款以及更老的通用客车以及装有SDM安全气囊控制系统的轻型卡车来说,气囊警告灯点亮是驾驶员判别SIR系统出现故障的关键。当警告灯持续点亮或闪烁时,如果汽车仍在行驶,就可能发生下述一个或多个故障现象:①撞车时安全气囊不发生作用;②没发生撞车时安全气囊发生作用;③撞车时安全气囊不能如正常情况下完全起作用。如果车主发现安全气囊警告灯点亮或闪烁,应立即对车辆进行维修。 | John A Meir 学书 | 2002 | 汽车维修与保养2002,,1: | 10 |
| 20 | Infected pancreatic necrosis: Not necessarily a late event in acute pancreatitis显示文摘It is widely believed that infection of pancreatic necrosis is a late event in the natural course of acute pancreatitis. This paper discusses the available data on the timing of pancreatic infection. It appears that infected pancreatic necrosis occurs early in almost a quarter of patients. This has practical implications for the type, timing and duration of preventive strategies used in these patients. There are also implications for the classification of severity in patients with acute pancreatitis. Given that the main determinants of severity are both local and systemic complications and that they can occur both early and late in the course of acute pancreatitis, the classification of severity should be based on their presence or absence rather than on when they occur. To do otherwise, and in particular overlook early infected pancreatic necrosis, may lead to a misclassification error and fallacies of clinical studies in patients with acute pancreatitis. | Maxim S Petrov Vincent Chong John A Windsor | 2011 | World Journal of Gastroenterology2011,17,27: | 10 |