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12篇 您的检索式:作者名="JOSe MG"
    题名 作者 年代 出处 被引量
1Implication of polyeomb members Bmi-1, Mel-18, and Hpc-2 in the regulation of pl6INK4A, pl4ARF, hTERT, and c-Myc expression in primary breast carcinomas显示文摘Javier S Jose MG Cristina P 2006Clin Cancer Res2006,12,23:1
2Ghrelin prevents cisplatin-induced mechanical hyperalgesia and cachexia显示文摘Jose MG Juan PC Dougherty PM 0,,:1
3Use of irbesartan to maintain sinus rhythm in patients with long-lasting persistent atrial fibrillation 显示文摘Madrid AH Bueno MG Jose MG 2002Circulation2002,106,:1
4EGF-induced activation of AKT resuhs roTOR-dependent p70S6 kinase phospholylation and inhibition of HC11 cell lactogenic differentiation 显示文摘Galbaugh T Cerrito MG Jose CC Cutler ML 2006BMC Cell Biol2006,7,34:1
5Attitudes towards disability in education through the SSCI ( 2000- 2011 ) : A topical and biblio- metric analysis 显示文摘JOSe MG CeNDIDO JI MARIA VJ 2013Electr J Res Educ Psychol2013,11,1:1
6Use of irbesartan to maintain sinus rhythm in patients with long-lasting persistent atrial fibrillation: a prospective and randomized study显示文摘Madrid AH Bueno MG Rebollo Jose MG 2002Circulation2002,106,:1
7Anticonvulsant effect of cytoskeletal depolymerizers in combination with potassium channel opener and adenylate cyclase activator,a causative link with nerve growth factor显示文摘Tyagi MG Jose VM 2001Indian J Exp Biol2001,39,5:1
8Spontaneous thrombosis of cerebral aneurysms presenting with ischemic stroke显示文摘Jose EC Eyal Y John MG 2007J Neurol Sci2007,254,12:1
9Regional distribution of mitochondrial dysfunctionand apoptotic remodeling in pacing induced heart failure显示文摘Jose MG Michael JG 2009J Cardiac Fail2009,15,:1
10Implications of p53 gene mutations on patient survival in transitional cell carcinoma of the bladder: A long-term study显示文摘Antonio SS Juan GL Jose MG et ol 2008Urol Oncol2008,26,6:1
11Spontaneous thrombosis ofcerebral aneurysms presenting with ischemic stroke 显示文摘Jose EC Eyal Y John MG 2007JNeurosci2007,254,12:1
12Does a biological link exist between periodontitis and rheumatoid arthritis?显示文摘Periodontitis or Periodontal disease(PD) and Rheumatoid arthritis(RA) are two the most common chronic inflammatory diseases. Periodontitis is a biofilm associated destructive inflammatory disease of the periodontium caused by specific microorganisms. Rheumatoid arthritis is an autoimmune condition and is identified by elevated serum autoantibody titre directed against citrullinated peptides or rheumatoid factor. Periodontitis may involve some elements of autoimmunity. Recent studies have established that PD and RA show a common pathway and could be closely associated through a common dysregulation and dysfunction in inflammatory mechanism. The enzyme peptidyl arginine deiminase(PAD), expressed by Porphyromonas gingivalis(P. gingivalis) is responsible for the enzymatic deimination of arginine residuals to citrulline resulting in protein citrullination and its increased accumulation in RA.Citrullination by PAD may act as a putative biologic link between PD and RA. Association of Human leukocytic antigen-DR4 antigen has been established both with RA and PD. Several interleukins and inflammatory mediators(ILs) and Nuclear factor kappa beta ligand are linked to these common chronic inflammatory diseases. Antibodies directed against heat shock protein(hsp 70 ab) of P. gingivalis, P. melanogenicus and P. intermedia are raised in PD as well as RA. Both the conditions share many pathological and immunological similarities. Bacterial infection, genetic susceptibility, altered immune reaction and inflammatory mediators considered responsible for RA are also associated with PD. So it is plausible that a biological link may exist between PD and RA. Therapies aimed at modifying the expression and effect of inflammatory mediators and effector molecules such as matrix metalloproteinases, proinflammatory cytokines and autoantibodies of structural proteins may probably reduce the severity of both RA and PD.Rosamma Joseph MG Jose Raj Shobha Sundareswaran Priyanka Chand Kaushik Amol Vijay Nagrale Susan Jose Sreeraj Rajappan 2014World Journal of Rheumatology2014,4,3:0
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