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179篇 您的检索式:作者名="JUAN G C"
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1Laparoscopic and robot-assisted laparoscopic digestivesurgery:Present and future directions显示文摘Laparoscopic surgery is applied today worldwide to most digestive procedures. In some of them, such as cholecystectomy, Nissen's fundoplication or obesity surgery, laparoscopy has become the standard in practice. In others, such as colon or gastric resection, the laparoscopic approach is frequently used and its usefulness is unquestionable. More complex procedures, such as esophageal, liver or pancreatic resections are, however, more infrequently performed, due to the high grade of skill necessary. As a result, there is less clinical evidence to support its implementation. In the recent years, robot-assisted laparoscopic surgery has been increasingly applied, again with little evidence for comparison with the conventional laparoscopic approach. This review will focus on the complex digestive procedures as well as those whose use in standard practice could be more controversial. Also novel robot-assisted procedures will be updated.Juan C Rodríguez-Sanjuán Marcos Gómez-Ruiz Soledad Trugeda-Carrera Carlos Manuel-Palazuelos Antonio López-Useros Manuel Gómez-Fleitas 2016World Journal of Gastroenterology2016,22,6:27
2Evaluation of VEGF gene polymorphisms and proliferative diabetic retinopathy in Mexican population显示文摘● AIM: To assess if the included vascular endothelial growth factor(VEGF) polymorphisms rs3025035, rs3025021 and rs2010963 are associated to proliferative retinopathy in a Mexican population with type 2 diabetes mellitus(T2DM).● METHODS: A case-control study was conducted in adult individuals with T2 DM associated to proliferative retinopathy or non-proliferative retinopathy from Oct. 2014 to Jun. 2015 from the Retina Department of the Asociation to Prevent Blindness in Mexico. The selected patients were adults with a diagnosis of T2 DM ≥5y. All subjects had a comprehensive ocular examination and the classification of the retinopathy severity was made considering the Early Treatment Diabetic Retinopathy Study(ETDRS) standardization protocols. Genomic DNA was extracted from whole fresh blood. All samples were genotyped by q PCR for selected VEGF polymorphisms. Hardy-Weinberg equilibrium was calculated by comparing Chi-square values between the expected and the observed values for genotype counts.● RESULTS: In total 142 individuals were enrolled, 71 individuals with T2 DM and associated proliferative retinopathy and 71 individuals with non-proliferative retinopathy. One-sided Fisher's exact test was performed for rs3025021[OR(95% CI)=0.44(0.08-2.2); P=0.25] and rs2010963 [OR(95% CI)=0.63(0.25-1.6); P=0.23]. The minor allelic frequencies obtained were 26% for rs3025021, 10% for rs3025035 and 61% for rs2010963. The pairwise linkage disequilibrium between the three SNP was assessed, and was as follows: rs3025021 vs rs3025035: D'=1.0, r^2=0.1043, P≤0.0001; rs3025021 vs rs2010963: D'=0.442, r^2=0.0446, P=0.149; rs3025035 vs rs2010963: D'=0.505, r^2=0.0214, P=0.142.● CONCLUSION: This is the first analysis involving VEGFA polymorphisms and proliferative diabetic retinopathy in a Mexican population. A major finding of the present study is that none of the polymorphisms studied was significantly associated with proliferative retinopathy. Based on these results, we can infer that different populations have different associations for the same polymorphisms.Roberto Gonzalez-Salinas Maria C Garcia-Gutierrez Gerardo Garcia-Aguirre Virgilio Morales-Canton Raul Velez-Montoya Vidal R Soberon-Ventura Victoria Gonzalez Rodrigo Lechuga Pablo Garcia-Solis David G Garcia-Gutierrez Marco Vinicio Garcia-Solis Manuel Saenz de Viteri Juan C Solis-S 2017International Journal of Ophthalmology(English edition)2017,10,1:12
3Celiac disease serology in patients with different pretest probabilities: Is biopsy avoidable?显示文摘AIM: To establish the diagnostic performance of sev-eral serological tests, individually and in combination, for diagnosing celiac disease (CD) in patients with different pretest probabilities, and to explore potential se- rological algorithms to reduce the necessity for biopsy. METHODS: We prospectively performed duodenal biopsy and serology in 679 adults who had either high risk (n = 161) or low risk (n = 518) for CD. Blood samples were tested using six assays (enzyme-linked immunosorbent assay) that detected antibodies to tissue transglutaminase (tTG) and deamidated gliadin peptide (DGP). RESULTS: CD prevalence was 39.1% in the high-risk population and 3.3% in the low-risk group. In high-risk patients, all individual assays had a high diagnostic efficacy [area under receiving operator characteristic curves (AU ROC): 0.968 to 0.999]. In contrast, assays had a lower diagnostic efficacy (AU ROC: 0.835 to 0.972) in the low-risk group. Using assay combinations, it would be possible to reach or rule out diagnosis of CD without biopsy in 92% of cases in both pretest populations. We observed that the new DGP/tTG Screen assay resulted in a surplus compared to more conventional assays in any clinical situation. CONCLUSION: The DGP/tTG Screen assay could be considered as the best initial test for CD. Combinations of two tests, including a DGP/tTG Screen, might be able to diagnose CD accurately in different clinical scenarios making biopsy avoidable in a high proportion of subjects.Emilia Sugai María L Moreno Hui J Hwang Ana Cabanne Adriana Crivelli Fabio Nach-man Horacio Vázquez Sonia Niveloni Julio Argonz Roberto Mazure Graciela La Motta María E Caniggia Edgardo Smecuol Néstor Chopita Juan C Gómez Eduardo Maurińo Julio C Bai 2010World Journal of Gastroenterology2010,16,25:4
4输尿管及膀胱深部浸润型子宫内膜异位症的手术治疗效果显示文摘目的报告泌尿道子宫内膜异位症的手术治疗效果以及探讨保守型手术和根治性手术的选择。方法对5个手术科室参与的输尿管或膀胱深部浸润型子宫内膜异位症外科治疗的CIRENDO前瞻性数据库管理数据进行回顾性研究。对术前、术中和术后数据结果进行分析。结果数据库中的数据显示,30例中有15例为输尿管子宫内膜异位症,14例为膀胱结节病变(bladder nodules),1例同时存在这2种类型的病变。输尿管松解术14例,其中输尿管完全恢复解剖解构10例。4例40岁以上的患者术后出现闭经和可忍受的中度输尿管狭窄,其中3例好转,1例行二次输尿管切除和输尿管膀胱吻合术。4例初次手术行输尿管切除术。5例输尿管标本中发现2例输尿管子宫内膜异位症。4例并发症中有2例与输尿管结节病灶切除有关,2例与膀胱子宫内膜异位病灶切除有关。远期效果较为满意,如疼痛症状显著改善、泌尿系不适症状消失,仅有1例较长时间膀胱神经功能障碍。结论建议保守性手术联合术后假绝经疗法治疗大多数泌尿道子宫内膜异位症。尽管总体结果满意,由于术中可能同时施行其他一些复杂手术如结直肠手术,术后并发症的风险仍不容忽视。陈旭 刘彦 Francisc Rozsnyai Horace Roman Benoit Resch Fabrice Dugardin Juan Berrocal Gérme Descargues Remi Schmied Malik Boukerrou Loc Marpeau CIRENDO Study Group 2013中国微创外科杂志2013,13,2:3
5Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19.Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral 2021Cellular & Molecular Immunology2021,18,9:2
6An RTP/RTCP based approach for multimedia group and inter stream synchronization显示文摘FERNANDO B S JUAN C G C JAIME L M 2008Multimedia Tools and Applications2008,40,2:1
7Determinants of paten rights:A cross-national study 显示文摘Juan C Ginarte Walter G Park 1997Resrarch Policy1997,26,3:1
8The Performance Effect of Organizational Learning and Market Orientation显示文摘Daniel J J Juan G C 2007Industrial Marketing Management2007,36,:1
9Does Intracoronary Abciximab Improve the Outcome of Percutaneous Coronary Interventions? A Randomized Controlled Trial显示文摘Jose G Juan SR Isabel C 2006Rev Esp Cardiol2006,59,6:1
10Nitrate prmotes biological oxidation of sulfide in wastewaters:Experiment at plant-scale biotech显示文摘Juan G L Alfonso C Juan M G 2006Bioeng2006,93,4:1
11Is the application of carbendazimharmful to healthy plants?Evidence of weak phytotoxicity in tobacco显示文摘Pablo C G Juan M R Rosa M R 2002Journal of Agricultural and Food Chemistry2002,50,:1
12Experimental and full scale pilot plant constructed wetlands for municipat wastewaters treatment显示文摘Gemma A Juan M G Ruben C and Estanistao de L 2003Ecological Engineering2003,21,1:1
13Supervisory control of an adaptive-droop regulated DC microgrid with battery mana- gement capability 显示文摘TOMISLAV D JOSEP M G JUAN C V 2014IEEE Transactions on Power Electronics2014,29,2:1
14A neuro-immune mode for discriminating and visualizing anomalies显示文摘Fabio A.G Juan C G Diego A R 0,,03:1
15Transit Rider- ship Forecasting at Station Level: An Approach Based on Distance-decay Weighted Regression 显示文摘JAVIER G OSVALDO D C JUAN C G 2011Journal of Trans- port Geography2011,19,6:1
16The role of pH in the melanin biosynthesis pathway 显示文摘Francisco G C Francisco G C Juan V S 1982The Journal of Biological Chemis- try1982,257,15:1
17An input-output balance study for PCBs in humans显示文摘Juan C Y Thomas G O Sweetman A J Jones K C 2002Environment International2002,28,3:1
18Dynamic Buckling of Anchored Steel Tanks Subjected to Horizontal Earthquake Excitation 显示文摘Juan C V Luis A G Luis E S 2006Journal of Constructional Steel Research2006,62,6:1
19Effect of eight benthic diatoms as feed on the growth of red abalone (Haliotis rufescens) postlarvae显示文摘JUAN G C R MAIADEL P S S MARíA T V 0,,04:1
20Genetic variability related to serum uric acid concentration and risk of Parkinson’s disease显示文摘Isabel González‐Aramburu Pascual Sánchez‐Juan Silvia Jesús Ana Gorostidi Eduardo Fernández‐Juan Fátima Carrillo María Sierra Pilar Gómez‐Garre María T. Cáceres‐Redondo José Berciano Javier Ruiz‐Martínez Onofre Combarros Pablo Mir Jon Infante 2013Mov Disord2013,,:1
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