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您的检索式：作者名="Jack Feehan"
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| 1 | The role of D-dimer in relation to the clinical course of patients with COVID-19显示文摘In recent times,systemic coagulation,fibrinolysis,and cardio-pulmonary injury has been recognized in patients with COVID-19,the clinical disease state caused by infection of the novel coronavirus,SARS-CoV-2.While originally believed to be a primary lower respiratory infection,as more cases are identified,treated,and examined,hematologic complications are being identified as a significant driver of morbidity and mortality associated with the disease.Elevated D-dimer levels(>1µg/ml)on hospital admission have been identified as being associated with increased mortality[1],and levels greater than 2µg/ml predict fatal outcomes in patients[2].Alongside these results,there is also a greater risk of thrombotic events in COVID-19 patients,with risk increasing to as high as 31%[3],and pulmonary embolism risk increases proportionately alongside this[4].Whilst understanding of the pathophysiology is incomplete,there is clearly a component of coagulative disorder in these patients.D-dimer could prove a valuable tool to identify patients who are likely to have poorer outcomes and allow for prophylactic treatment and monitoring of secondary complications(Fig.1). | Marijan Bosevski Gorjan Krstevski Golubinka Bosevska Kosta Kapsarov Emilija Dodic Jack Feehan Lily Stojanoska Vasso Apostolopoulos | 2021 | Acta Biochimica et Biophysica Sinica2021，53，1： | 0 |
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