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276篇 您的检索式:作者名="Jacob L S"
    题名 作者 年代 出处 被引量
1血管紧张素转换酶抑制剂和血管紧张素受体拮抗剂的使用与2019冠状病毒疾病检测阳性之间的关系显示文摘血管紧张素转换酶抑制剂(angiotensin-converting enzyme inhibitor,ACEI)和血管紧张素受体拮抗剂(angiotensin receptor blocker,ARB)在2019新型冠状病毒疾病(coronavirus disease 2019,COVID-19)全球大流行背景下的作用备受争议。此类药物是治疗一些慢性病的必须药物,有建议停止使用这些药物.Mehta N KalraA Nowacki AS Anjewierden S Han Z Bhat p Rubio AEC Jacob M Procop GW Harrington S Milinovich A Svensson LG Jehi L Young JB Chung MK 周卫(译) 叶鹏(校) 2020中华高血压杂志2020,28,5:9
2Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack显示文摘S Claiborne Johnston Peter M Rothwell Mai N Nguyen-Huynh Matthew F Giles Jacob S Elkins Allan L Bernstein Stephen Sidney 20072007 (9558)2007,,9558:3
3Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source显示文摘BACKGROUND The trans-fat containing AMLN(amylin liver non-alcoholic steatohepatitis,NASH)diet has been extensively validated in C57BL/6J mice with or without the Lep^ob/Lep^ob(ob/ob)mutation in the leptin gene for reliably inducing metabolic and liver histopathological changes recapitulating hallmarks of NASH.Due to a recent ban on trans-fats as food additive,there is a marked need for developing a new diet capable of promoting a compatible level of disease in ob/ob and C57BL/6J mice.AIM To develop a biopsy-confirmed mouse model of NASH based on an obesogenic diet with trans-fat substituted by saturated fat.METHODS Male ob/ob mice were fed AMLN diet or a modified AMLN diet with trans-fat(Primex shortening)substituted by equivalent amounts of palm oil[Gubra amylin NASH,(GAN)diet]for 8,12 and 16 wk.C57BL/6J mice were fed the same diets for 28 wk.AMLN and GAN diets had similar caloric content(40%fat kcal),fructose(22%)and cholesterol(2%)level.RESULTS The GAN diet was more obesogenic compared to the AMLN diet and impaired glucose tolerance.Biopsy-confirmed steatosis,lobular inflammation,hepatocyte ballooning,fibrotic liver lesions and hepatic transcriptome changes were similar in ob/ob mice fed the GAN or AMLN diet.C57BL/6J mice developed a mild to moderate fibrotic NASH phenotype when fed the same diets.CONCLUSION Substitution of Primex with palm oil promotes a similar phenotype of biopsyconfirmed NASH in ob/ob and C57BL/6J mice,making GAN diet-induced obese mouse models suitable for characterizing novel NASH treatments.Michelle L Boland Denise Oro Kirstine S T■lb■l Sebastian T Thrane Jens Christian Nielsen Taylor S Cohen David E Tabor Fiona Fernandes Andrey Tovchigrechko Sanne S Veidal Paul Warrener Bret R Sellman Jacob Jelsing Michael Feigh Niels Vrang James L Trevaskis Henrik H Hansen 2019World Journal of Gastroenterology2019,25,33:3
4Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack显示文摘S Claiborne Johnston Peter M Rothwell Mai N Nguyen-Huynh Matthew F Giles Jacob S Elkins Allan L Bernstein Stephen Sidney 2007The Lancet . 2007 (9558)2007,,9558:2
5Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack显示文摘S Claiborne Johnston Peter M Rothwell Mai N Nguyen-Huynh Matthew F Giles Jacob S Elkins Allan L Bernstein Stephen Sidney 2007The Lancet2007,,9558:2
6OMEGA EP high-energy petawatt laser: progress and prospects显示文摘D N Maywar J H Kelly L J Waxer S F B Morse I A Begishev J Bromage C Dorrer J L Edwards L Folnsbee M J Guardalben S D Jacobs R Jungquist T J Kessler R W Kidder B E Kruschwitz S J Loucks J R Marciante R L McCrory D D Meyerhofer A V Okishev J B Oliver G Pien 2008Journal of Physics: Conference Series2008,,3:1
7Phylogeneticsof Panicoideae (Poaceae) based on chloroplast and nuclear DNAsequences 显示文摘Teerawatananon A Jacobs S W L Hodkinson T R 2011Telopea2011,13,11:1
8Relationship of MIC to efficacy of cefotaxime in treatment of Streptoooccus pneumoniae infections 显示文摘 Kaplan S L Schutze G E 1996Antimicrob Agents Chemother1996,40,:1
9Survival of children pa-tients with systemic lupus erythematosus显示文摘Massardo L Martinez ME Jacobeli S 0,,:1
10Dietary intake and health effects of selected toxic elements显示文摘Oliveirada S A L Barrocas P G Jacob S C 2005Brazil Journal of Plant Physiology2005,17,:1
11Software strategies for portable computer energy management 显示文摘Jacob R L Alan J S 1998IEEE Personal Communications1998,5,3:1
12Endophytic fungi in indigenous Australian grasses associated with toxicity to livestock显示文摘Miles C O di Menna M E Jacob S W L 1998Applied and Environmental Microbiology1998,64,:1
13Homocysteine as arisk factor for ischem icstroke: an epidem iological story in evolution 显示文摘SACCO R L ROBERTS J K JACOBS B S 1998Neuroepidemiology1998,17,4:1
14Multi-objective Optimization of Fiber Reinforced Composite Laminates for Strength,Stiffness and Minimal Mass显示文摘Jacob L Pelletier Senthil S 2006Computers & Structures2006,84,2930:1
15Astrocytes prevent abnormal neuronal development in the fragile X mouse 显示文摘JACOBS S DOERING L C 2010J Neurosci2010,30,12:1
16Synthesis of 1,2- disubstitued benzimidazoles using SiO2/ZnCl2 显示文摘Jacob R G Dutra L G Radatz C S 2009Tetrahedron Letter2009,50,13:1
17Genome sequence and analysis of the tuber crop potato显示文摘Xu X Pan S Cheng S Zhang B Mu D Ni P Zhang G Yang S Li R Wang J Orjeda G Guzman F Tones M Lnzano R Ponce O Martinez D De la Cruz G Chakrabarti S K Patil V U Skryabin K G Kuznetsov B B Ravin N V Kolganova T V Beletsky A V Mardanov A V Di Genova A Bolser D M Martin D M Li G Yang Y Kuang H Hu Q Xiong X Bishop G J Sagredo B Mejia N Zagorski W Gromadka R Gawor J Szczesny P Huang S Zhang Z Liang C He J Li Y He Y Xu J Zhang Y Xie B Du Y Qu D Bonierbale M Ghislain M Herrera Mdel R Giuliano G Pietrella M Perrotta G Faeella P O 'Brien K Feingold S E Barreiro L E Massa G A Diambra L Whitty B R Vaillancourt B Lin H Massa A N Geoffroy M Lundback S DellaPenna D Buell C R Sharma S K Marshall D F Waugh R Bryan G J Destefanis M Nagy I Milbourne D Thomson S J Fiefs M Jacobs J M Nielsen K L Sonderkaer M Iovene M Tortes G A Jiang J Veilleux R E Bachem C W de Boer J Bonn T Kloosterman B van Eck H Datema E Hekkert B Goverse A van Ham R C Visser R G 2011Nature2011,475,7355:1
18Hospital variation in postoperative infection and out come after congenital heart surgery显示文摘Pasquali S K He X Jacobs M L 2013The Annals of thoracic surgery2013,96,2:1
19Endometrial tis- sue inperitoneal fluid显示文摘BARTOSIK D JACOBS S L KELLY L J 1986Fertil Steril1986,46,5:1
20Pneumatosis intestinalis in patients with ischemia:correlation of CT findings with viability of bowel显示文摘Kernagis L Y Levine M S Jacobs J E 2003AJR Am J Roentgenol2003,180,3:1
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