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795篇 您的检索式:作者名="Jacoby J"
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1Acute effects of rotavirus and malnutrition on intestinal barrier function in neonatal piglets显示文摘AIM: To investigate the effect of protein-energy malnutrition on intestinal barrier function during rotavirus enteritis in a piglet model.METHODS: Newborn piglets were allotted at day 4 of age to the following treatments:(1) full-strength formula(FSF)/noninfected;(2) FSF/rotavirus infected;(3) half-strength formula(HSF)/noninfected;or(4) HSF/rotavirus infected.After one day of adjustment to the feeding rates,pigs were infected with rotavirus and acute effects on growth and diarrhea were monitored for 3 d and jejunal samples were collected for Ussingchamber analyses.RESULTS: Piglets that were malnourished or infected had lower body weights on days 2 and 3 post-infection(P < 0.05).Three days post-infection,marked diarrhea and weight loss were accompanied by sharp reductions in villus height(59%) and lactase activity(91%) and increased crypt depth(21%) in infected compared with non-infected pigs(P < 0.05).Malnutrition also increased crypt depth(21%) compared to full-fed piglets.Villus:crypt ratio was reduced(67%) with viral infection.There was a trend for reduction in transepithelial electrical resistance with rotavirus infection and malnutrition(P = 0.1).3H-mannitol flux was significantly increased(50%;P < 0.001) in rotavirus-infected piglets compared to non-infected piglets,but there was no effect of nutritional status.Furthermore,rotavirus infection reduced localization of the tight junction protein,occludin,in the cell membrane and increased localization in the cytosol.CONCLUSION: Overall,malnutrition had no additive effects to rotavirus infection on intestinal barrier function at day 3 post-infection in a neonatal piglet model.Sheila K Jacobi Adam J Moeser Anthony T Blikslager J Marc Rhoads Benjamin A Corl Robert J Harrell Jack Odle 2013World Journal of Gastroenterology2013,19,31:4
2The effects of epithelial cell supernatant on contractions of isolated canine tracheal smooth muscle显示文摘Barnett K Jacoby D B Nadel J A 1988Am Rev Respir Dis1988,138,4:2
3Brand Choice Behavior asa Function of Information Load:Replication and Extension显示文摘Jacoby J Speller D Berning C 1974Journal of Consumer Research1974,1,1:1
4Platelet activation and function after trauma 显示文摘Jacoby RC Owings JT Holmes J 2001J Trauma2001,51,4:1
5The radiologic diagno- sis of quadriceps twndon rupture显示文摘Spector ED DiMm'cangelo MT Jacoby J H 1995N J Med1995,92,:1
6Fluoroquinolone- modifying enzyme: a new adaptation of a common aminoglyco- side acetyltransferase 显示文摘Robicsek A Strahilevitz J Jacoby G A 2006Nat Med2006,12,1:1
7Clinical practice guide- lines for the sustained use of sedatives and analgesics in the criti- cally ill adult显示文摘Jacobi J Fraser GL Coursin DB 2002Crit Care Med2002,30,1:1
8Addition of dexmedetomidine to standard sedation regimens after cardiac surgery: an outcomes analysis 显示文摘DASTA JF JACOBI J SESTI ABM 2006Pharmacotherapy2006,,6:1
9Fluoroquinolonemodifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase显示文摘Robicsek A J Strahilevitz G A Jacoby 2006Nat Med2006,12,1:1
10Agroecosystem resilience and farmer' perceptions of climate change impacts on cocoa farms in Alto Beni, Bolivia显示文摘Jacobi J Schneider M Bottazzi P 2013Renewable Agriculture and Food Systems2013,30,:1
11Platelet activation and function after trauma显示文摘Jacoby RC Owings JT Holmes J 2001J Trauma2001,51,4:1
12The influence of alanyl glutam ine on immunologic functions and morbility in postoperative to talparenteral nutrition显示文摘Jacobi CA Ordemann J Zuckermann H 1999Zentralbl Chir1999,124,3:1
13Tackling antibiotic resistance显示文摘Bush K Courvalin P Dantas G Davies J Eisenstein B Huovinen P Jacoby GA Kishony R Kreiswirth BN Kutter E Lerner SA Levy S Lewis K Lomovskaya O Miller JH Mobashery S Piddock LJ Projan S Thomas CM Tomasz A Tulkens PM Walsh TR Watson JD Witkowski J Witte W Wr 0,,:1
14Inhibition of peritoneal tumor cell growth and implantation in laparoscopic surgery in a rat model显示文摘 Ordemann J Bohm B 1997Am J Surg1997,174,:1
15Becoming famous overnight:Limits on the ability to avoid unconscious influences of the past显示文摘Jacoby L Kelley CM Brown J 1989Journal of Personality and Social Psychology1989,16,2:1
16Clinical practice guide- lines for the sustained use of sedatives and analgesics in the criti- cally ill adult显示文摘Jacobi J Fraser GL Coursin DB 2002Crit Care Med2002,30,3:1
17Adjuvant postop- erative radiation therapy after curative resection of squamous cell carcinoma of the thoracic esophagus: a prospective ran- domized study显示文摘Zieren H U Muller J M Jacobi C A 1995World J Surg1995,19,3:1
18Part I:presentation of the model显示文摘Thome J R Dupont V Jacobi A M Heat transfer model for evaporation in microchannels 2004Int J Heat Mass Transfer2004,47,1416:1
19The Components of Perceived Risk, Proceedings of the 3rd Annual 显示文摘Jacoby J Kaplan 1972Conference for Consumer Research1972,,:1
20Fluoroquinolone modifying enzyme:a new adaptation of a common aminoglycoside acetyltransferase显示文摘Robicsek A Strahilevita J Jacoby G A 2006Nat Med2006,12,:1
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