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1篇 您的检索式：作者名="Jacopo Colombini"

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		题名	作者	年代	出处	被引量
	1	Helicobacter pylori infection and asthma:Is there a direct or an inverse association?A meta-analysis显示文摘AIM:To analyze the consistency of a potential involvement of the bacterium infection in the asthma disease. METHODS:A systematic literature search of the terms 'Helicobacter pylori '(H. pylori) associated to 'asthma' using PubM ed,Scopus and the Cochrane Library Central was performed. Reference lists from published articles were also employed. Titles of these publications and their abstracts were scanned in order to eliminate duplicates and irrelevant articles. The criteria of inclusion of the studies were:Original studies; the H. pylori diagnostic method has been declared; all ranges of age have been included in our study; a definitive diagnosis of asthma has been reported.RESULTS:We selected 14 articles in which the association between the two conditions was addressed. In 7 studies the prevalence of H. pylori infection in the asthma population and in the control population was made explicit. There was heterogeneity between the studies(Cohran's Q = 0.02). The H. pylori infection in the asthma population resulted 33.6%(518 of 1542),while in the control population resulted 37.6%(2746 of 7310)(relative risk of H. pylori infection in the asthma population = 0.87,95%CI:0.72-1.05,P = 0.015,random effects model). Instead,considering the morevirulent strains,the majority of studies showed an inverse relationship between the prevalence of H. pylori infection and asthma.CONCLUSION:In our meta-analysis the prevalence of H. pylori infection in the asthma population resulted not statistically significant lower than in control population(P = 0.15). Instead,considering the more virulent strains,the majority of studies showed an inverse relationship between the prevalence of H. pylori infection and asthma.	Davide Giuseppe Ribaldone Sharmila Fagoonee Jacopo Colombini Giorgio Saracco Marco Astegiano Rinaldo Pellicano	2016	World Journal of Meta-Analysis2016，4，3：	1

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