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	题名	作者	年代	出处	被引量
1	Autophagy is increased in cryptorchid testis resulting in abnormal spermatozoa显示文摘Autophagy is invoIved in spermatogenesis by regulating germ cell maturation.This catabolic process increases with hyperthermic conditions to prevent the accumulation of damaged organelles.Cryptorchidism is associated with impairment of germ cell maturation revealed by the presence of immature forms of sperm cells in ejaculates.The aim of the present study was to evaluate the status of autophagy in sperm cells from cryptorchid patients.Semen samples of cryptorchid patients and normozoospermic controls were analyzed by immuno cytochemistry and electron microscopy.Autophagy protei ns,autophagy-related protein 9(ATG9)and microtubule-associated protein,lA/lB-light chain 3(LC3)were localized by immunocytochemistry on the acrosome and on the equatorial segment of sperm cells.LC3 was also detected in the midpiece of cryptorchid sperm tail.Autophagy substrate p62 protein was present in the acrosome and in the postequatorial segment of sperm in control samples,but not in the cryptorchid ones.Transmission electron microscopy revealed double-membrane-limited autophagosomes in postequatorial part of spermatozoa head and midpiece in cryptorchid samples.Partly degraded mitochondria were frequently discerned in autophagic vacuoles.In conclusion,autophagy is increased in sperm cells from patients with cryptorchid history comparatively to control.Our work provides insights into the role of autophagy in the maturation and survival of human male gametes in pathological conditions.Thus,regulating autophagy could represent a potential way to improve sperm quality in cryptorchid men.	Marina G Yefimova Antoine Buschiazzo Agnes Burel Marie-Therese Lavault Celine Pimentel Guilhem Jouve Sylvie Jaillard Bernard Jegou Nicolas Bourmeyster Celia Ravel	2019	Asian Journal of Andrology2019，21，6：	2
2	Effects of transforming growth factor-beta 1 on human adrenocoritical fasciculata-reticularis cell differentiated functions显示文摘	Lebrethon MC Jaillard C Naville D	1994	J Clin Endocrinol Metab1994，79，4：	1
3	Hidden dys- functioning in subacute stroke显示文摘	Jaillard A Naegele B Trabucco-Miguel S	2009	Stroke2009，40，：	1
4	The mechanisms of pain-induced pulmonary vasoconstriction : an experimental study in fetal lambs 显示文摘	Debarge VH Sicot B Jaillard S	2007	Anesth Analg2007，104，4：	1
5	Agarose as a suitable substrate for use in the study of Al dynamics in the rhizosphere显示文摘	Calba H Jaillard B Fallavier P	1996	Plant and Soil1996，178，1：	1
6	Predicting cognitive dysfunctioning in nondemented patients early after stroke显示文摘	Jaillard A Grand S Le Bas JF	2010	Cerebrovasc Dis2010，29，5：	1
7	Root-induced irreversible transformation of trioctahedral mica in the rhizosphere of rape 显示文摘	Hinsinger P Elsass F Jaillard B	1993	Journal of Soil Science1993，44，：	1
8	Phosphorus Deficiency Impairs Early Nodule Functioning and Enhances Proton Release in Roots of Medicago truncatula L.显示文摘	C. Tang P. Hinsinger J.J. Drevon B. Jaillard	2001	Annals of Botany2001，，1：	1
9	Predicting cognitive dysfunc-tioning in nondemented patients early after stroke 显示文摘	Jaillard A Grand S Le Bas JF	2010	CerebrovascDis2010，29，5：	1
10	Plant-microbe-soil interactions in the rhizosphere : an evolutionary perspective显示文摘	Lambers H Mougel C Jaillard B Hinsinger P	2009	Plant Soil2009，321，：	1
11	Vicarious func- tion within the human primary motor cortex? A longitudinal fMRI stroke study显示文摘	Jaillard A Martin CD Garamhois K	2005	Brain2005，128，5：	1
12	Predicting cognitive dysfunctioningin nondemented patients early after stroke显示文摘	Jaillard A Grand S Le Bas JF	2010	Cerebrovasc Dis2010，29，5：	1
13	Effects of phosphodiesterase 5 inhibitor on pulmonary vascular reactivity in the fetal lamb显示文摘	Jaillard S Larrue B Deruelle P	2006	Ann Thorac Surg2006，81，3：	1
14	Identification of genecopy number variations in patients with mental retardation using array-CGH:Novel syndroms in a large French series显示文摘	Jaillard S Drunat S Bendavid C	2010	Eur J Med Gennt2010，53，2：	1
15	Root-induced irreversible transformation of a triotahedral mica in the rhizophere of rape 显示文摘	Hinsinger P Elsass F Jaillard B	1993	Journal of Soil Science1993，44，25：	1
16	Sociedad Gelógica del Perú显示文摘	Carlotto V Jaillard E Carlier G		0，，：	1
17	Predicting cognitive dysfunction in nondepented patients early after stroke显示文摘	Jaillard A Grand S Le Bas JF		0，，：	1
18	Vicarious function within the human primary motor cortex? A longitudinal fMRI for stroke study显示文摘	Jaillard A Martin CD Garambois K	2005	Brain2005，128，5：	1
19	The disruption of the rod-derived cone viability gene leads to photoreceptor dysfunction and susceptibility to oxidative stress 显示文摘	Cronin T Raffelsberger W Lee-Riveral I Jaillard C Niepon ML Kinzel B	2010	Cell Death Differ2010，17，7：	1
20	Agarose as a suitable substrate for use in the study of Al dynamics in the rhizosphere显示文摘	Calba H Jaillard B Fallavier P	1996	Plant and Soil1996，178，：	1

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