|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 紫杉醇局部治疗抑制猪静脉桥新生内膜形成和增厚的实验研究显示文摘目的 :局部药物治疗是一个很好的防治静脉桥病变的策略。本研究用抗细胞增殖药物紫杉醇处理大隐静脉桥后植入猪的颈动脉 ,以观察紫杉醇的抗细胞增殖作用在抑制静脉桥内膜平滑肌细胞增殖、迁移导致内膜形成和增厚的效果。方法 :将 10头猪的 2 0只大隐静脉桥分为两组。治疗组 :将大隐静脉桥 10只置于含有 10 μmol/L浓度的紫杉醇溶液中 (先用该溶液灌洗 )浸泡 1h后植入猪的颈动脉 ,紫杉醇是溶解在 2 5 μl/L的无水酒精中 ,对照组 10只大隐静脉桥置于单纯的酒精中浸泡。 4周后取开放的静脉桥进行组织学分析。结果 :①治疗组静脉桥新生内膜面积 (1 5 9± 0 95 )mm2 ,对照组新生内膜面积高达 (2 43± 1 3 5 )mm2 ,治疗组显著低于对照组 ,两组比较有非常显著的差异 ,P <0 0 1;②治疗组内膜平滑肌细胞密度均值为 (3 681± 193 5 ) /mm2 ,对照组为 (4 60 7± 1993 ) /mm2 ,两组比较有显著性差异 ,P <0 0 5 ;中膜平滑肌细胞密度均值治疗组 (2 13 9± 73 4) /mm2 ,对照组(3 62 9± 3 2 0 7) /mm2 ,两组比较有显著性的差异 ,P <0 0 5。结论 :紫杉醇可显著抑制静脉桥内膜、中膜平滑肌细胞的增殖 ,抑制新生内膜的形成 ,证明紫杉醇可在防治静脉桥闭塞方面发挥独特作用。 | 吴隐雄 Martin H Chamberlain Thomas Johnson Jason L Johnson Andrew C Newby Gianni D Angelin Martin Oberhoff Karl K Karsch | 2003 | 中国循环杂志2003，18，6： | 2 |
| 2 | Some electrical effects of the adsorption of water vapour by anodized aluminum 显示文摘 | JASON A C WOOD J L | 1955 | Proceedings of the Physical Society1955，，68： | 1 |
| 3 | Combing new technologies for determination of phytoplankton community structure in the northern gulf of Mexico显示文摘 | JASON H S LISA C TAMMI L R | 2005 | Journal Plankton2005，41，： | 1 |
| 4 | Extraction and quan- tification of daidzein and genistein in food 显示文摘 | Jason L Ieslie J C Bluek W I | 1998 | Ana- lytical Biochemistiy1998，264，1： | 1 |
| 5 | Specific contact resistivity of tunnel barrier contacts used for Fermi level depinning显示文摘 | ROY A M JASON L J Y SARASWAT K C | 2010 | IEEE Electron Device Letters2010，31，10： | 1 |
| 6 | Selective determination of amino acids using flow injection analysis coupled with chemiluminescence detection 显示文摘 | JASON W C PAUL S F SIMON W L | 2003 | Anal Chim Acta2003，480，： | 1 |
| 7 | Loss of INI 1 expression is characteristic of both conventional and proximal-type epithelioid sarcoma显示文摘 | Jason H L Paola D C Christopher F D M | 2009 | Am J Surg Pathol2009，33，4： | 1 |
| 8 | Identification and composi- tion of phenolic compounds in the preparation of oolong tea manu, factured by semifermentation and drying processes 显示文摘 | Dou J P Viola S Y L Jason T C T | 2007 | J Aric Food Chem2007，55，： | 1 |
| 9 | Jackson Divergent effects of matrix metalloproteinases 3, 7,9, and 12 on atherosclerotic plaque stability in mouse brachiocephalic arteries显示文摘 | JASON L J SARAH J G ANDREW C | 2005 | PNAS2005，102，15： | 1 |
| 10 | The molecular basis for apoptotic defects in patients with CD95 (Fas/APO-1) mutations显示文摘 | AKSHAY K V JASON R O JIA L C | 1999 | J Clin Invest1999，103，： | 1 |
| 11 | Internal hemorrhoid harboring adenocarcinoma:A case report显示文摘BACKGROUND The incidence of carcinoma found within an internal hemorrhoid specimen is exceptionally rare.Further,the presence of primary anal canal adenocarcinoma within internal hemorrhoids is even more infrequent.We describe a case in which anal canal adenocarcinoma was found within an internal hemorrhoidectomy specimen and perform a review of the current literature.CASE SUMMARY The patient was a 79-year-old male who presented with rectal bleeding and was found to have large thrombosed internal hemorrhoids during screening colonoscopy.The patient subsequently underwent a three-column hemorrhoidectomy.Pathologic analysis revealed one of three specimens containing a 1.5 cm moderate-to-poorly differentiated adenocarcinoma of anal origin with superficial submucosal invasion.At three-month follow up,he was taken to the operating theatre for biopsy and re-excision of his non-healing wound,which showed no recurrence.His wound has since healed and he was cancer free at ten-month follow up.CONCLUSION When faced with primary anal canal adenocarcinoma an interdisciplinary approach to treatment should be considered.Routine pathological analysis of hemorrhoidectomy specimens may be beneficial due to the severity of anal canal carcinomas if left undiagnosed and untreated in a timely manner. | Michael L Caparelli Jason C Batey Anisha Tailor Timothy Braverman Cory Barrat | 2021 | World Journal of Gastrointestinal Oncology2021，13，1： | 1 |
| 12 | Effect of sesame antioxidants on LPS-induced NO production by BV2 microglial cells 显示文摘 | Hou Rolis Chien-Wei hen Huan-Lian l zen Jason T C | 2003 | Neuroreport2003，4，14： | 1 |
| 13 | Post-curing effects on marine vartm frp composite material properties for test and implementation显示文摘 | Jason J C Nathan L P John J L | 2006 | Journal of Engineering Materials and Technology-Transaction of the ASME2006，128，1： | 1 |
| 14 | Evaluation of radiation dose and positioning accuracy on X-ray volume imaging system for image-guided radiotherapy显示文摘 | Jason C Chia L Jian W | 2008 | Nucl Instrum Meth Phys Res2008，266，： | 1 |
| 15 | The importance of preoperative Hemoglobin Evaluation in large volume liposuction 显示文摘 | Umar H C Petr H Jason L | 2008 | Ann Plast Surg2008，61，3： | 1 |
| 16 | The contemporary physical and chemical flux of aeolian dust:A synthesis of direct measurements of dust deposition显示文摘 | COREY R L JASON C | 2009 | Chemical Geology2009，267，1： | 1 |
| 17 | Bisphenol A is released from polycarbonate drinking bottles and mimics the neurotoxic actions of estrogen in developing cerebellar neurons显示文摘 | HOA H L EMILY M C JASON P C | 2008 | Toxicology Letters2008，176，2： | 1 |
| 18 | Role of disinfectant concentration and pH in the inactivation kinetics of Cryptosporidium parvum oocysts with ozone and monochloramlne 显示文摘 | Jason L R Jae H K Benito C V | 2001 | Environmental Science and Technology2001，35，13： | 1 |
| 19 | Measurements of Thermal Gradients and Their Effects on Segmental Concrete Bridge显示文摘 | ROBERTS C L BREEN J E JASON C | 2002 | Journal of Bridge Engineering2002，7，3： | 1 |
| 20 | Bmwnson and Bonnie Spring, Implementing Evidence - Based Praeflee Education in Social Work : A Transdiseiplinary Apprcaeh 显示文摘 | Jennifer L Bellamy Edward J Mullen Jason M Sattcrficld Robin P Newhouse Molly Ferguson Ross C | 2013 | Research on Social Work Prae- flee2013，，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员