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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | Image quality of sparse -aperture designs for remote sensing显示文摘 | Robert D F Theodore A T Jason R C | 2002 | Optical Engineering2002，41，8： | 1 |
| 3 | An atomic-level of melting using femtosecond electron diffraction显示文摘 | BRADLEY J S JASON R D ROBERT E J | 2003 | Science2003，302，21： | 1 |
| 4 | An atomiclevel of melting using femtosecond electron diffraction显示文摘 | BRADLEY J S JASON R D ROBERT E J | 2003 | Science2003，302，21： | 1 |
| 5 | Optimal stochastic fault detection filter显示文摘 | Robert H D Lewis M Jason L | 2003 | Automatica2003，39，： | 1 |
| 6 | The effect of employee trust of the supervisor on enterprising behavior:a cross-cultural comparison显示文摘 | ROBERT C D RICHARD I C JASON B J SELIM I S ET AL | 2006 | Journal of Business and Psychology2006，，21： | 1 |
| 7 | A Multi-dimensional Study of Trust in Organization显示文摘 | Robert D C Selim S I Jason J B | 1998 | Journal of Managerial Issue1998，10，： | 1 |
| 8 | Image quality of sparse-aperture designs for remote sensing显示文摘 | Robert D F Theodore A T Jason R C | 2002 | Optical Engi- neering2002，41，8： | 1 |
| 9 | Platelet-Mediated Modulation of Adaptive Immunity显示文摘 | Bennett D Elzey Jun Tian Robert J Jensen Axel K Swanson Jason R Lees Steven R Lentz Colleen S Stein Bernhard Nieswandt Yiqiang Wang Beverly L Davidson Timothy L Ratliff | 2003 | Immunity2003，，1： | 1 |
| 10 | Enhancing douglasfir pulp properities with a combination of enzyme treatments and fiber fraction 显示文摘 | Shawn D Mansfield Jason Swanson D Norm Roberts | 1999 | Tappi Journal1999，82，： | 1 |
| 11 | Enhancing Douglas-fir pulp properties with a combination of enzyme treatments and fiber fractionation显示文摘 | Mansfield Shawn D Jason Swanson D Norm Robert | 1999 | Tappi1999，82，5： | 1 |
| 12 | A multi-dimensional study of trust in organizations显示文摘 | ROBERT D C SELIM S T JASON J B | 1998 | Journal of managerial Tssue1998，，10： | 1 |
| 13 | Microwave activation of enzymatic catalysis显示文摘 | Yang Douglas D Nichols Jason Kelly Robert M | 2008 | J Am Chern Soc2008，130，10： | 1 |
| 14 | A Multi-Dimensional Study of Trust in Organizations 显示文摘 | ROBERT D C SELIM S T JASON J B | 1998 | Journal of Managerial Tissue1998，，10： | 1 |
| 15 | 心尖球形综合征1例显示文摘2006年1月,一43岁女性因胸闷、心悸、头晕、出汗1h就诊于作者所在医院急诊科。患者诉4个月前首次出现上次症状,此后发作逐渐频繁,病情加重,且与劳累和情绪因素无关。经检查并无心脏病危险因素存在。 | Harriette G C Van Spall Jason D Roberts Anna M Sawka Carol J Swallow Susanna Mak 陈栋(译) | 2008 | 世界临床医学2008，2，1： | 0 |
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